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4 D's
Distress dysfunction deviance dangerousness
Distress
Significant internal discomfort
Dysfunction
Impairment in daily life
Deviance
Culturally unexpected behavior/thoughts
Dangerousness
Danger to self or others
Continuum of experience
Typical → disordered with no clear cutoff
Categorical diagnosis
Have it or don't
Dimensional diagnosis
Where you fall on a spectrum
DSM-5-TR
U.S. mental disorder diagnostic manual
ICD-11
International diagnostic system
Sign
Objective observable evidence
Symptom
Subjective patient experience
Diagnosis
Identifies symptom cluster NOT cause
Differential diagnosis
Distinguish disorders with similar symptoms
Comorbidity
2+ diagnoses in one person
Clinical judgment
Evidence-based reasoning NOT opinion
Etiology
Cause/origin of a disorder
Biological model
Disorders linked to biological processes
Neuroplasticity
Brain changes with experience
Neurotransmitters
Chemicals carrying signals between neurons
NT imbalance theory
Too many/few NTs or altered receptors
NT theory limitation
Too simplistic + hard to measure
Epigenetics
Environment changes gene expression NOT sequence
Endocrine system
Glands release hormones into blood
HPA axis
Stress/fight-or-flight system
Sickness behavior
Inflammation → fatigue/anhedonia/sleep-appetite changes
Biological model strength
Researchable + produces new knowledge
Biological model weakness
Can overemphasize medication
Operant conditioning
Learning through consequences
Reinforcement
Makes behavior more likely
Positive reinforcement
Add something rewarding
Negative reinforcement
Remove something unpleasant
Classical conditioning
Learning through association
Stimulus generalization
Fear spreads to similar stimuli
Little Albert
Fear learned through conditioning
Little Peter
Fear unlearned through exposure
Behavioral model strength
Testable + supports effective therapy
Behavioral model weakness
Can ignore cognition
Cognitive model
Thoughts/beliefs affect emotion and behavior
Causal attribution
Meaning assigned to an event
Global assumptions
Broad beliefs about self/world
Placebo effect
Positive effect from expectation
Nocebo effect
Negative effect from expectation
Cognitive model strength
Useful + researchable
Cognitive model weakness
Hard to prove thoughts cause disorder
Diathesis-stress
Predisposition + stress → disorder
Equifinality
Different causes → same outcome
Multifinality
Same cause → different outcomes
Case study
Detailed study of one person
Case study strength
Can support/challenge theories
Case study weakness
Cannot generalize well
Epidemiology
Patterns of disorders in populations
Prevalence
Existing cases at a given time
Incidence
NEW cases over a period
Risk factor
Increases likelihood of disorder
Protective factor
Decreases likelihood of disorder
Experimental method
Can establish causation
Randomization
Random group assignment
Why randomize?
Reduce confounds/selection bias
Confound
Outside variable affecting results
RCT
Randomized study of an intervention
Control group
No treatment/comparison group
Experimental group
Receives treatment
Statistical significance
Does an effect exist?
Clinical significance
Is the effect meaningful/useful?
Human lab study
Controlled exposure to study effects
Internal validity
Effect is due to independent variable
Sleep + mental health
Strongly linked in both directions
Dyssomnia
Problem with sleep quality
Parasomnia
Behavior/experience during sleep
Circadian rhythm
Internal sleep-wake clock
Strongest circadian cue
Light-dark cycle
Other circadian cues
Meals activity social interaction
SCN
Master clock in hypothalamus
Melanopsin
Light-detecting receptor for circadian rhythm
Melatonin
Hormone regulating sleep timing
Sleep benefit
Clears metabolic waste
Beta-amyloid
Alzheimer's-linked waste cleared during sleep
Partial sleep deprivation
Reduced/disrupted sleep
Lack of sleep consolidation
Interrupted sleep
Selective stage deprivation
Loss of specific sleep stages
Reduced sleep duration
Not enough total sleep
Insomnia: sleep symptoms
Trouble starting/staying asleep or waking early
Insomnia: daytime requirement
Must cause daytime impairment
Insomnia opportunity rule
Not caused by inadequate sleep opportunity
Insomnia frequency
≥3 nights/week
Acute insomnia
Chronic insomnia
≥3 months
Predisposing insomnia factors
Vulnerability before insomnia
Precipitating insomnia factors
Trigger that starts insomnia
Perpetuating insomnia factors
Behaviors maintaining insomnia
Bed + wakefulness
Classical conditioning can maintain insomnia
CBT-I
Behavioral/cognitive treatment for insomnia
Insomnia medication
Can help but has limitations
Abnormal anxiety
Excessive + impairing + out of proportion
Panic attack
Acute fear with ≥4 symptoms
Panic attack somatic symptoms
HR sweat tremble SOB choking chest pain etc.
Panic attack cognitive symptoms
Fear dying or losing control
Panic disorder
Attacks + ≥1 month worry/behavior change
Panic differential
Rule out medical causes