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Growth Hormone
most important hormone in epiphyseal plate activity
Thyroid Hormone
modulates activity of growth hormone, ensures proper proportions
Testosterone (males) Estrogen (females)
at puberty, growth spurts
Hormone Control
Negative feedback loop, control Ca+ levels in blood
Parathyroid Hormone
responds to low blood calcium, stimulates osteoclasts to resorb blood to release calcium
Calcitonin
produced by thyroid gland in response to high calcium levels
Mechanincal Stress
weight pulling them down
Wolff’s Law
handedness results in thicker and stronger bones, opposite can happen though