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These flashcards cover key concepts, terms, and definitions related to bone tissue and its physiology, development, and functions.
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Bone Tissue
The living skeleton composed of dynamic tissues that include cells, nerves, and blood vessels.
Osteology
The study of bone.
Support
The function of bones providing structural support for the body and soft organs.
Protection
The function of bones in safeguarding vital organs such as the brain and spinal cord.
Movement
Bones act as levers for muscle action, facilitating body movement.
Hematopoiesis
Blood cell formation that occurs in red marrow cavities of certain bones.
Osteocalcin
A hormone secreted by bones that helps regulate insulin secretion and glucose levels.
Axial Skeleton
The division of the skeleton consisting of the skull, vertebral column, and rib cage.
Appendicular Skeleton
The division of the skeleton that includes bones of the upper and lower limbs and girdles.
Long Bone
A bone that is longer than it is wide.
Short Bone
A bone that is as long as it is wide.
Flat Bone
A wide, flat bone that serves protective functions.
Irregular Bone
A bone that does not fit into established classifications.
Sesamoid Bone
A type of irregular bone entirely encased in tendon or ligamentous tissue.
Bone Matrix
The composition of bone made up of organic and inorganic materials.
Hydroxyapatite
A crystallized calcium phosphate salt that constitutes 85% of bone minerals.
Mineral Composition of Bone
Bones contain minerals like calcium carbonate, fluoride, sodium, potassium, and magnesium.
Composite Material
A combination of a ceramic (hydroxyapatite) and a polymer (collagen) in bone.
Compact Bone
The dense outer layer of bone that appears smooth and solid.
Spongy Bone
Bone made of trabeculae, featuring small, needle-like or flat pieces.
Trabeculae
The small, needle-like or flat pieces of bone in spongy bone.
Periosteum
The connective tissue membrane covering the exterior of bones.
Endosteum
The membrane covering the interior surface of bones.
Red Marrow
Myeloid tissue that produces blood cells found in specific bones.
Yellow Marrow
Fatty marrow that does not produce blood and is found in long bones.
Osteons
The functional unit of compact bone, consisting of concentric lamellae.
Lamellae
Layers of bone tissue that form the structure of osteons.
Canaliculi
Hair-like canals that connect lacunae and central canals, allowing communication between osteocytes.
Lacunae
Small cavities in bone tissue that contain osteocytes.
Osteoclasts
Bone-dissolving cells responsible for the resorption of bone.
Osteoblasts
Bone-forming cells responsible for synthesizing the bone matrix.
Osteocytes
Former osteoblasts trapped in the matrix that maintain bone tissue.
Intramembranous Ossification
The process of bone formation within a fibrous membrane, forming flat bones.
Endochondral Ossification
The process of replacing hyaline cartilage with bone, forming most of the skeleton.
Calcification
The hardening process of bone, where osteoid becomes mineralized.
Ossification Center
A cluster of osteoblasts where bone formation begins.
Epiphyseal Plate
A zone of hyaline cartilage between epiphysis and diaphysis, where bone lengthening occurs.
Growth Plates
Regions in long bones where cartilage growth and bone elongation take place.
Hypocalcemia
A condition of low calcium levels in the blood, leading to excitability of the nervous system.
Hypercalcemia
Excessive calcium levels in the blood, resulting in muscle weakness and emotional disturbances.
Calcitonin
A hormone released by the thyroid gland that lowers blood calcium levels.
Parathyroid Hormone (PTH)
A hormone that raises blood calcium levels by increasing osteoclast activity.
Mineralization
The process where ions from blood are deposited into bone tissue.
Mineral Resorption
The process by which osteoclasts dissolve bone and release minerals back into the blood.
Bone Remodeling
The continuous process of renewing bone tissue throughout life.
Calcium Homeostasis
The balance maintained between calcium intake, losses, and exchange with bone.
Phosphate Homeostasis
Regulation of phosphate levels in the body influenced by hormones.
Fracture Types
Categorization of fractures including closed, open, transverse, spiral, and comminuted.
Stress Fracture
A break in a bone caused by abnormal stress.
Pathological Fracture
A fracture occurring in a bone weakened by disease.
Fracture Healing
The physiological process of repairing broken bones.
Closed Reduction
The manipulation of bone fragments to normal positions without surgery.
Open Reduction
Surgical procedure for aligning broken bones with plates or screws.
Cast
A device used to immobilize and stabilize healing bones.
Hematoma Formation
The initial stage of fracture healing characterized by blood clot formation.
Soft Callus Formation
The stage where collagen and fibrocartilage convert granulation tissue to a soft callus.
Hard Callus Formation
The deposition of a temporary bony collar around fracture sites.
Bone Physiology
The metabolic activity associated with mature bone, including maintenance and remodeling.
Osteogenic Cells
Stem cells that can differentiate into various bone cell types.
Osteoblast
Cells that form new bone matrix.
Osteoclast
Cells that break down bone tissue.
Ectopic Ossification
The abnormal formation of bone in soft tissue.
Spongy Bone
Bone that has a porous structure providing strength with minimal weight.
Calcification Zones
Zones in the epiphyseal plate where cartilage matrix becomes calcified.
Appositional Growth
The process of bone growth in width, occurring at the bone surface.
Regeneration
The process leading to the repair and restoration of bone structure after injury.
Bone Density
A measurement of the amount of mineral content in bone, often linked to strength.
Osteoporosis
A condition characterized by reduced bone density and increased fracture risk.
Exercise and Bone Health
The stimulation of bone growth and remodeling through mechanical stress from physical activity.
Translation of Forces
The mechanism by which mechanical forces are applied to bones, influencing their shape and strength.