Parasitt Credit 1: Trypanosomatidae: Genus - Leishmania

Leishmania tropica causes:

cutaneous leishmaniosis

Vectors of leishmania:

Sandflies
(Phlebotomus spp., Lutzomyia spp.)

Diagnosis of Leishmaniosis is based on:

finding macrophages full of amastigote in stained slide of vertebrate organs

the division of leishmania

visceral,
cutaneous,
mucocutaneous

Visceral leishmaniosis is caused by:

L. Donovani

What causes cutaneous leishmaniosis?

L. Tropica major
L. Tropica minor
L. Peruviana

What causes mucocutaneous leishmania?

- L. Brasiliensis Complex
- L. Mexicana Complex

Leishmania reproduce by:

binary fission

Life cycle of leishmania:

1. amastigote infect Sandfly (vector)
2. midgut: amastigote => procyclic promastigote
3: Intestine: binary fission
4. Pharynx: => metacyclic promastigote
5. Infect new host when sucking blood
6. macrophage phagocyted by
macrophage.
7. turns into amastigote + protective vacuole around
8. binary fission until machrophage burst
9. released amastigote can infect new macrophages, infect new vector, or cluster in visceral organs, skin and mucos

What is the form of leishmania in the blood?

amastigote