Cardio & Respiratory Wk 12 - Anti-arrhythmic drugs
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48 Terms
What class is Quinidine in?
Class IA
3 multiple choice options
What class is Lidocaine in?
Class IB
3 multiple choice options
What are the drugs in Class II?
Atenolol, Sotalol, Propanolol
3 multiple choice options
What are the drugs in Class III?
Amiodarone, Ketodoxapram, Sotalol
3 multiple choice options
What Class is Diltiazem in?
Class IV
3 multiple choice options
What drugs are calcium channel blockers?
diltiazem
3 multiple choice options
What channels do class III drugs block?
Potassium channels
3 multiple choice options
What is the target for class II drugs?
Beta adrenergic receptors
3 multiple choice options
What is the target for lidocaine and quinidine?
Sodium channels
3 multiple choice options
What is the target for Terbutaline and how does it interact with it?
Beta adrenergic receptor agonist
3 multiple choice options
What drugs are muscarinic receptor antagonists?
Atropine and Glycopyrrolate
3 multiple choice options
What drug is a weak class 1 drug?
Lidocaine
3 multiple choice options
What drug is a moderate class 1 drug?
Quinidine
3 multiple choice options
What is Quinidine used for?
Atrial fibrillation in horses
3 multiple choice options
What is lidocaine used for?
Ventricular tachycardia caused by DAD and reentry
3 multiple choice options
What drugs treat tachycardia caused by pacemaker problems?
Propanolol, atenolol, sotalol
3 multiple choice options
What drugs treat ventricular tachycardia caused by EAD and reentries?
Amiodarone and sotalol
3 multiple choice options
What does amiodarone and ketodoxapram treat?
Atrial fibrillation
3 multiple choice options
What does diltiazem treat?
Supraventricular tachycardia caused by EAD and reentries
3 multiple choice options
What treats bradycardia caused by pacemakers issues?
Terbutaline, atropine, glycopyrrolate
3 multiple choice options
What is the PK for quinidine?
Slows phase 0 depolarisation and slows conductivity through atria, ventricles, and His-perkinje
3 multiple choice options
What drug slows phase 0 depolarisation and slows conductivity through atria, ventricles, and His-perkinje?
Lidocaine
3 multiple choice options
What drugs cause a widening of the QRS complex and increases RR interval?
Lidocaine and Quinidine
3 multiple choice options
What are the adverse effects for Quinidine?
Hypotension, Laminitis, respiratory system issues, colic, arrhythmias
3 multiple choice options
What are the adverse effects for lidocaine?
Vomiting, anorexia, depression, seizures, nausea
3 multiple choice options
What is the acronym we use for Class II drugs?
HAVCARP
3 multiple choice options
What does H stand for in HAVCARP?
Reduce heart rate
3 multiple choice options
What does av stand for in HAVCARP?
Alters AV node
3 multiple choice options
What does CA stand for in HAVCARP?
Decreases intracellular calcium overload
3 multiple choice options
What does R stand for in HAVCARP?
Decrease repolarisation current
3 multiple choice options
What does P stand for in HAVCARP?
Decrease pacemaker rate
3 multiple choice options
How does atenolol, sotalol, and propanolol affect the ECG?
Prolonged PR interval and decrease SA node automaticity
3 multiple choice options
What are the adverse effects for Class II drugs?
No adverse effects
3 multiple choice options
What is the PK for Class III drugs?
Prolonged action potential duration and refractory period, slow repolarisation in atria and ventricular mycoytes
3 multiple choice options
What drug inhibits the upregulation of TASK-1 channels?
Ketodoxapram
3 multiple choice options
What drugs cause prolonged RT interval?
Class III drugs
3 multiple choice options
What drugs are dobermans more susceptible to?
Amiodarone
3 multiple choice options
What are the adverse effects of amiodarone?
Vomiting, anorexia, neutropenia, thrombocytopenia, hepatotoxicity
3 multiple choice options
What drugs are going to slow phase 0 depolarisation of the SA and AV node and reduce heart rate?
Diltiazem
3 multiple choice options
How will Diltiazem affect the ECG?
Prolonged PR interval and RR interval
3 multiple choice options
What are the adverse effects of Diltiazem?
Excessive depression of blood pressure, cardiac contractility, AV conduction
3 multiple choice options
When do you not want to avoid using Diltiazem?
with ventricular tachycardia
3 multiple choice options
What drugs cause an increase in heart rate, SA node depolarisation, AV node conduction, and rate of repolarisation of atrial and ventricular myocytes?
Terbutaline
3 multiple choice options
What drugs will cause a narrowing of the QRS complex and shortened PR interval?
Terbutaline
3 multiple choice options
What are the adverse effects for Terbutaline?
Tremors, excitement, dizziness, increased heart rate
3 multiple choice options
How fast does atropine work?
30-60 min
3 multiple choice options
When is glycopyrrolate used?
Premed for anesthesia
What are the adverse effects of atropine and glycopyrrolate?
Sinus tachycardia, Increased salivation, constipation
3 multiple choice options