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Summarize the sequence of events in the development of the fetal nervous system. Understand neuroanatomical planes and directional terms. Name the major divisions of the brainstem and midbrain, and identify key functions performed by each.
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Early neural development stages
Ectoderm a outer layer of embryo tissue thickens and creates a neural plate
the neural plate folds inward (concaves) creating a neural groove
the neural groove ends folds into a cannoli, and fuse together within following weeks
at 4th week its completely fused and created the neural tube
the neural tube will eventually go on to form the spinal cord
Ectoderm
starts flat, folds in and becomes the neural tube
Neural Tube and what it develops into (brain FMH
and spinal cord parts)
develops into the spinal cord and the brain (CNS)
the tube divides into 3 parts of the brain
(first the forebrain - front,
midbrain - middle,
hindbrain- back)
the rest forms the spinal cord
first 3 parts then spilt into 5 (tho mid brain doesnt technichally spilt)
Forebrain
(prosencephalon)
what does it divide into?
front part of neural tube
will splits into
the telecephalon or cerebral hemispheres
diecephalon - thalamus, hypothalamus
Midbrain
(menescephalon)
what does it divide into?
stays as the midbrain no spilting
Hindbrain
(rhocephalon)
what does it divide into?
develops into
metecephalon - cerebellum and pons
myelecephalon - medulla
why does kink in neural tube stays in humans
because we are bipedal, and we keep kink in the neural tube, while 4 legged animals get that kink straightened out
which part of the brain evolved the earliest?
the hindbrain because the back of the brain is responsible for the most basic functions we need to survive
Anatomical Conventions (what are different cuts, planes)
useful for seeing parts of brain
Horizontial plane
saggital plane
Coronal cut
Horizontial plane
cuts brain horizontally, view from above
saggital plane
cuts brain vertically in half
Coronal cut
cuts brain into a front and back. tiara cut
Anterior
General front
Posterior
General back
Rostral
front of brain (upper on diagnol)
Caudal
back of the brain (lower on diagnol)
Medial
Middle (in between side to side)
Lateral
side to side (ex. from right to left hemisphere)
Brain is symetrical (mostly)
if you cut the brain in hald you’ll find the two hemispheres, and most structures are paired or mirrored, some exceptions,
hesmispheres connected by corpis callosum
Contralateral control
each side of brain controls and takes in information from the opposite side of the body.
(ex move right hand, left side of brain is being used)
damage on right hemisphere you’ll have prblems controling the left side
ipsilateral control
same side control
Brain stem (function and parts)
controls breathing heart rate, swallowing
used to relay info from spinal cord to the brain and to spinal cord
midbrain
pons
medulla
Pons (funciton and parts)
connects the crebellum and the brain
controls sensroy and motor processing
nuclei of the cranial nerves (bunc=dle of grey matter in CNS)
(remember there are 12 and in pairs, few highlights
CN 5 - chewing facial senation
abducens - eye movement
facial - facial sensations
vestibulocochlear - hearing and balance
Medulla (funciton and parts)
responsible for basic vital functions, dmage here is thus fatal since it controls breathing, heart rate, blood pressure regulation
sensory, motor processing
contains nuclei of cranial nerves 9-12
glossopharyngeal
vagus - main nerve of ANS, main control of medulla
accessory
hypoglossal
Midbrain (funciton and parts)
Tectum
Tegmentum
Tectum (midbrain)
roof/back processes sensory info,
has bumps called
superiors and interior collcululi (pair)
superior (rostrral bumps)
res ponsible for sound and visual processing.
inferior (caudal bumps)
sound processing
superiorcollcululi
from tectum of midbrain
res ponsible for sound and visual processing.
interior collcululi
from tectum of midbrain
sound processing
Tegmentum - midbrain (know cranial nerves)
motor control, nuclei of cranial nerves, moves eye
cranial nerves 3 and 4 moves eye
oculomotor: opening eye
trochlea: eye movement
red nucleus - motor control
substantial nigra - dopamine, reward, motor control
Penaqueductal gray - pain perception
reticular motion - sleep and arousal, motor control, temp regulation
oculomotor:
from tegmentum of midbrain
cranial nerve that
opening eye
Trochlea
from tegmentum of midbrain
cranial nerve that moves eye
Red nucleus
from tegmentum of midbrain
motor control
Substanstil nigra
from tegmentum of midbrain
dopamin reward center, motor control
Penaqueductal gray
from tegmentum of midbrain
pain perception
Recticular motor
(sounds like testicular like waking up wiith wood)
from tegmentum of midbrain
sleep, arousal, motor control , temp regulation