Cardiovascular System Test

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A closed system of the heart and blood vessels
* The heart pumps blood
* Blood vessels allow blood to circulate to all parts of the body
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Functions of the cardiovascular system
Transport oxygen, nutrients, cell wastes, hormones to and from cells
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Heart size and location
* Size of a human fist, weighing less than a pound
* Located in the thoracic cavity, between the lungs in the inferior mediastinum
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Orientation
* Apex is directed toward left hip and rests on the diaphragm
* Base points toward right shoulder
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Pericardium
a double-walled sac
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Fibrous pericardium
is loose and superficial
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Serous membrane
is deep to the fibrous pericardium and composed of two layers
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Parietal pericardium:

1. outside layer that lines the inner surface of the fibrous pericardium
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Visceral pericardium:

1. next to heart; also known as the *epicardium*
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Serous fluid fills
the space between the layers of pericardium, called the *pericardial cavity*
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Epicardium
* Outside layer; the visceral pericardium
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Myocardium
* Middle layer
* Mostly cardiac muscle
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Endocardium
* Inner layer known as *endothelium*
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Atria (right and left)
* Receiving chambers
* Assist with filling the ventricles
* Blood enters under low pressure
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Ventricles (right and left)
* Discharging chambers
* Thick-walled pumps of the heart
* During contraction, blood is propelled into circulation
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Interatrial septum
* Separates the two atria longitudinally
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Interventricular septum
Separates the two ventricles longitudinally
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Heart functions as a double pump
* Arteries carry blood away from the heart
* Veins carry blood toward the heart
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Double pump
* Right side works as the pulmonary circuit pump
* Left side works as the systemic circuit pump
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Pulmonary circulation
* Blood flows from the right side of the heart to the lungs and back to the left side of the heart
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Blood is pumped…
 out of right side through the pulmonary trunk, which splits into pulmonary arteries and takes oxygen-poor blood to lungs
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Oxygen-rich blood returns…
* to the heart from the lungs via pulmonary veins
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Systemic circulation
Oxygen-rich blood returned to the left side of the heart is pumped out into the aorta
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Blood circulates to
* systemic arteries and to all body tissues
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Left ventricle has thicker walls because…
* it pumps blood to the body through the systemic circuit
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Oxygen-poor blood returns to…
* the right atrium via systemic veins, which empty blood into the superior or inferior vena cava
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**Heart Valves**
* Allow blood to flow in only one direction, to prevent backflow
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Atrioventricular (AV) valves
* —between atria and ventricles
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Left AV valve:
bicuspid (mitral) valve
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Right AV valve:
tricuspid valve
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Semilunar valves
* —between ventricle and artery
* Pulmonary semilunar valve
* Aortic semilunar valve
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AV valves
* Anchored the cusps in place by chordae tendineae to the walls of the ventricles
* Open during heart relaxation, when blood passively fills the chambers
* Closed during ventricular contraction
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Semilunar valves
* Closed during heart relaxation 
* Open during ventricular contraction
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Valves open and close in response…
* to pressure changes in the heart
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Blood in the heart chambers…
* does not nourish the myocardium
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The heart has its own nourishing circulatory system consisting of:
* coronary arteries
* cardiac veins
* coronary veins
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Coronary arteries
* —branch from the aorta to supply the heart muscle with oxygenated blood
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Cardiac veins
* drain the myocardium of blood
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Coronary sinus
a large vein on the posterior of the heart; receives blood from cardiac veins
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Blood empties into…
* the right atrium via the coronary sinus
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Two systems regulate heart activity
* Autonomic nervous system
* Intrinsic conduction system, or the nodal system
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Atrioventricular (AV) node is…
* at the junction of the atria and ventricles
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Tachycardia
rapid heart rate, over 100 beats per minute
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Tunica intima forms a friction-reducing lining
Endothelium
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Tunica externa forms protective outermost covering
* Mostly fibrous connective tissue
* Supports and protects the vessel
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Intrinsic conduction system, or the nodal system does
* Sets the heart rhythm
* Composed of special nervous tissue
* Ensures heart muscle depolarization in one direction only (atria to ventricles)
* Enforces a heart rate of 75 beats per minute
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Sinoatrial( SA) node
* Located in the right atrium
* Serves as the heart’s pacemaker
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Atrioventricular (AV) bundle (bundle of His) and bundle branches

\
* are in the interventricular septum
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Purkinje fibers spread
* within the ventricle wall muscles
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The sinoatrial node (SA node)
* starts each heartbeat
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Impulse spreads
through the atria to the AV node
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Atria

\
* contract
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At the AV node,
the impulse is delayed briefly
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Impulse travels
* through the AV bundle, bundle branches, and Purkinje fibers
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Ventricles contract
* blood is ejected from the heart
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Bradycardia
* low heart rate, less than 60 beats per minutes
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The *cardiac cycle* refers to

\
* one complete heartbeat, in which both atria and ventricles contract and then relax
* Systole = contraction
* Diastole = relaxation
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Average heart rate
* approximately 75 beats per minute
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Cardiac cycle length
* normally 0.8 second
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Blood vessels form
* a closed vascular system that transports blood to the tissues and back to the heart
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Vessels that carry blood away from the heart
* Arteries and arterioles
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Vessels that play a role in exchanges between tissues and blood
* Capillary beds
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Vessels that return blood toward the heart
* Venules and veins
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Three layers (tunics)
* in blood vessels (except the capillaries)
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Tunica media
* Smooth muscle and elastic tissue
* Controlled by sympathetic nervous system
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Arteries have
a heavier, stronger, stretchier tunica media than veins to withstand changes in pressure
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Veins have
* a thinner tunica media than arteries and operate under low pressure
* Veins also have valves to prevent backflow of blood
* Lumen of veins is larger than that of arteries
* Skeletal muscle “milks” blood in veins toward the heart
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Capillaries
* Only one cell layer thick (tunica intima)
* Allow for exchanges between blood and tissue
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Form networks called *capillary* *beds* that consist of:
* A vascular shunt
* True capillaries
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Blood flow through a capillary bed is known as
*microcirculation*