Lecture 1.2.2 Principles of Antimicrobial Therapy

What are the 3 types of antimicrobial therapy?

Prophylaxis

Empiric

Definitive

Which of the following describes treatment given to prevent an infection that has not yet developed?

A) Prophylaxis

B) Empiric

C) Definitive

A) Prophylaxis

Which of the following is described as treatment to prevent an infectious process from developing?

A) Primary prophylaxis

B) Secondary prophylaxis

C) Tertiary prophylaxis

A) Primary prophylaxis

* Example: antibiotics given before surgery to prevent surgical site infection

Which of the following is described as treatment to prevent an infection reccurance?

A) Primary prophylaxis

B) Secondary prophylaxis

C) Tertiary prophylaxis

B) Secondary prophylaxis

Which of the following is described as treatment to decrease the effects or spread of an infection?

A) Primary prophylaxis

B) Secondary prophylaxis

C) Tertiary prophylaxis

C) Tertiary prophylaxis

Which of the following describes initial antimicrobial therapy regimen based on presumptive infectious diseases?

A) Prophylaxis

B) Empiric

C) Definitive

B) Empiric

* Treats the suspected/most likely pathogens at the site of infection

A(n) _____ aids in the selection of empiric antimicrobial regimen while awaiting culture/susceptibility results.

Antibiogram

Which percentage level of an antibiogram would be considered great to use?

Okay to use? Hesitate to use?

> 90% (great to use)

80-90% (okay to use)

< 80% (hesitate to use)

Which of the following is true of empiric antibiotic therapy? Select 2 that apply.

A) Should be used for the longest duration

B) Should be used for the shortest duration

C) Should be broad spectrum

D) Should be narrow spectrum

B) Should be used for the shortest duration

C) Should be broad spectrum

* May use combination therapy

Which of the following is true of defnitive antibiotic therapy?

A) Should be broad spectrum

B) Should be narrow spectrum

B) Should be narrow spectrum

* Targeted therapy

Which of the following is a benefit of using shorter duration of broad spectrum therapy?

A) Decrease resistance

B) Increased patient compliance

C) Decreased adverse events

D) Decreased overall collateral damage

E) All of the above

E) All of the above