Chapter 9- Cannabis

marijuana

leaves and flower of cannabis plant

cannabis

plant itslef

hemp

fiber of cannabis plant

states that allow both medical and recreation used of marijuana

Illinois, Michigan, Colorado, California, Arizona

What level of marijuana does WI allow

CBD/Low THC program

financial benefits to legalization of marijuana

reduce court costs, gain revenue

sativa

higher THC/CBD, more cerebral high

indica

higher CBD/THC, more sedation, alleviating pain

phytocannabinoid examples

THC (psychoactive component) and CBD (antioxidant, anticonvulsant, anti-inflammatory, anti-anxiety, antipsychotic)

part of cannabis plant that has most THC

flowering heads and top leaves

Synthetic cannabinoid Dronabinol

appetite enhancer, decreases nausea

synthetic cannabinoid K2

sprayed on leaves, more intense effects compared to THC

ROA

smoked or ingested

Cannabinoid receptors found in brain and body

basal ganglia, cerebellum, hippocampus, cortex, amygdala, eyes, pancreas, testes, uterus

endocannabinoid examples

Anandamide (AEA0 and 2-AG

retrograde transmitter

release postsynaptic and bind to presynaptic

acute effects

affected appetite, elevated heart rate, decrease sperm count, euphoria, immune function and thirst

negative effects

higher heart rate and blood pressure, increase risk for lung disease, impaired fertilization, increase risk of schizophrenia, cognitive deficits, legal risks, decreases reaction time and coordination

medical and therapeutic uses to cannabis

treat chronic pain, cancer treatment, alleviate muscle stiffness, anti-inflammatory, stroke, Alzheimer’s disease, diabetes, IBS, depression, reduce use of opioid, alcohol, and cocaine

chronic effects

tolerance, dependence, addiction

withdrawal effects

cravings, irritability, aggression, nausea, depression, weight loss