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Asthma definition
Chronic inflammatory airway disorder with REVERSIBLE airflow limitation
Most common trigger of asthma exacerbation
Upper respiratory infection
Asthma medication triggers
NSAIDs, beta-blockers (ACE inhibitors worsen cough)
Asthma late-phase response
4-6 hr later; symptoms recur/worsen
Severe asthma exacerbation
Dyspnea at rest, RR >30, HR >120, PEFR <=40%
Life-threatening asthma
Can't speak, profuse sweating, drowsy/confused, PEFR <25%
Asthma action plan red zone
Peak flow <50%, severe dyspnea, minimal speech
Silent chest
Wheezing stops in severe distress = almost no airflow; EMERGENCY, not improvement
Asthma O2 targets
PaO2 >=60, SpO2 >90%
Status asthmaticus treatment
High-flow O2, continuous nebulized SABA, ipratropium, IV magnesium, IV steroids
First-line asthma rescue drug
SABA (albuterol)
Frequent SABA use means
Poorly controlled asthma
LABA
Maintenance only, not rescue
Ipratropium
Anticholinergic bronchodilator, combined with SABA in exacerbations
Long-term asthma control foundation
Inhaled corticosteroids (budesonide, beclomethasone)
PE most common source
DVT
PE other emboli types
Fat (long-bone fractures), air, tumor
PE most common symptom
Sudden dyspnea
PE signs
Tachypnea, tachycardia, pleuritic chest pain, cough/hemoptysis, crackles
Massive PE signs
Sudden mental status change, hypotension, impending doom, arrest
PE risk factors
Immobility, recent surgery, prior VTE, cancer, obesity, oral contraceptives, smoking, long flights, pregnancy
PE first-line diagnostic test
CT pulmonary angiography
PE test if contrast allergy
V/Q scan
Most definitive PE test
Pulmonary angiography (invasive)
PE ABG
Hypoxemia + respiratory alkalosis (not diagnostic)
D-dimer
Not specific or sensitive enough to diagnose PE
PE primary treatment
Anticoagulation
Preferred anticoagulant for acute PE
LMWH (enoxaparin); no aPTT needed
Long-term PE anticoagulant
Warfarin (at least 3-6 months)
Massive PE treatment
Fibrinolytic (alteplase)
IVC filter
When anticoagulation contraindicated/ineffective; prevents new emboli, doesn't dissolve clots
Heparin monitoring
aPTT + platelets (HIT)
Warfarin monitoring
INR
PE nursing priorities
Semi-Fowler's, O2, IV access, monitor VS/ABGs, reduce anxiety
PE prevention
Early ambulation, SCDs, prophylactic heparin/LMWH, hydration
Anticoagulant teaching
Take exactly as prescribed; report bruising, hematuria, black stools; follow-up labs