Viral diseases 1

Varicella Zoster Infections

Primary varicella-zoster virus (VZV) infection in seronegative individuals are known as

Varicella Zoster Infections

Secondary or reactivated disease is known as

Chicken Pox Varicella

Whole body and extremities are involved

Chicken Pox Varicella

Self limiting
Common In children

Chicken Pox Varicella

Vesicular eruption of trunk and head and neck occurring in crops

Chicken Pox Varicella

Life threatening

Chicken Pox Varicella

fever, malaise other

Symptomatic treatment

Varicella zoster virus

etiology of varicella zoster infections

Varicella Zoster Infections

acute, extremely contagious

2 weeks

incubation period of varicella zoster infections

airborne droplets, direct contact, RT (respiratory tract)

mode of transmission of varicella zoster infections

Varicella Zoster Infections

Fever chills, malaise headache, rash

Varicella Zoster Infections

Vesicular eruption that becomes pustular and eventually ulcerates

Varicella Zoster Infections

Successive crops of new lesions appear owing to repeated waves of viremia

herpes zoster / shingles

Reactivation that happens only in one side

Self limiting

herpes zoster / shingles

Vesicles, rash, ulcers unilateral along dermatome

herpes zoster / shingles

Predisposing immunosuppressive states like stress, malignancies, drug administration, HIV infection, RT, Pt w compromised immune response

herpes zoster / shingles

Sensory nerves of the trunk and head and neck (unilateral oral, facial and ocular)

Ramsay Hunt Syndrome

facial auditory nerve involvement, paralysis of the face

diagnosis of herpes zoster / shingles

fluorescent antibody staining, viral and serologic cultures; cytologic smears

Tzanck test

look form multi nucleated giant cells and intranuclear inclusions

herpes simplex meds effective

treatment of herpes zoster / shingles

prodromal of herpes zoster / shingles

headache, nasopharyngitis, anorexia, maculopapular rash or vesicular eruptions, low grade fever

herpes zoster / shingles

7-10 days clinical course

trunk - face - extremities

Pattern of eruption for herpes zoster / shingles

herpes zoster / shingles

Vesicle rupture forming superficial crust, heald by desquamation

herpes zoster / shingles

small blister like lesion that rupture forming small eroded ulcers w/ red margin (aphthous lesion)

Varicella Pneomositis

complication of Varicella Zoster Virus

Disseminated Varicella

scattered vesicles and crusted papules across different areas

Pleomorphism

various stage of evolution are present simultaneously in the same area

Post herpetic neuralgia

pain persisting in the area after the rash has healed

high dose of acyclovir, valacyclovir, famciclovir,

initiated immediately

herpes zoster / shingles treatment

intravenous (IV) acyclovir

what treatment should give if the patient is has severely compromised shingles