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28 Terms

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Pharmacology

The science of looking at the composition, effects, and uses of drugs.

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Nursing Role in Pharmacologic Care

Nurses are responsible for understanding the effect of medications on the disease process, providing interventions, monitoring plans, and educating patients.

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Safe Medication Administration

A set of principles to ensure proper patient care includes right patient, medication, route, dose, reason, time, assessment, documentation, education, and the right to refuse.

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Medication Reconciliation

The process of comparing a patient's medication orders to all medications the patient is taking to prevent errors.

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Controlled Substances Act

Federal legislation that regulates the manufacture, importation, possession, use, and distribution of certain substances.

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Pharmacokinetics

The study of how the body processes a drug, covering absorption, distribution, metabolism, and excretion.

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Half-Life

The time it takes for the concentration of a drug in the bloodstream to decrease by half.

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Adverse Effects

Undesired effects of medications that can be harmful or cause complications.

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Anticholinergic Effects

Effects resulting from the blockage of the parasympathetic nervous system, leading to symptoms like dry mouth and blurred vision.

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Look-Alike/Sound-Alike Medications

Drug names that may be confused due to their similar appearance or pronunciation, increasing the risk of medication errors.

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Peak and Trough Levels

Measurements of drug concentration in the blood; peak is the highest level after administration, while trough is the lowest level before the next dose.

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Agonist

A substance that occupies and activates receptors to produce a desired effect.

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Antagonist

A substance that occupies receptors but does not activate them, preventing agonists from exerting their effects.

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Pharmacodynamics

The interaction between a drug and its target receptors or sites in the body.

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CYP-450 System

A group of enzymes critical to the metabolism of drugs, affecting how drugs are processed by the body.

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Off-Label Use

Use of a medication for an indication not approved by the FDA.

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High Alert Medications

Medications that have a heightened risk of causing significant harm if used in error.

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Patient Education Regarding Medications

Providing patients with vital information about their medications including uses, administration, and potential side effects.

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Opioids

A class of drugs that include prescription pain relievers, known for their pain-relieving properties and high potential for addiction.

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Efficacy

The ability of a drug to produce the desired therapeutic effect.

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Therapeutic Index

The ratio between the toxic and therapeutic concentrations of a drug.

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Biotransformation

The chemical modification made by an organism on a chemical compound.

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Drug Interactions

The effect that occurs when two or more drugs react with each other, potentially altering their effects.

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Polypharmacy

The concurrent use of multiple medications, which is particularly common in older populations.

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Active Metabolites

Metabolites of a drug that have a pharmacological effect, potentially increasing the drug's efficacy or toxicity.

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Generic Drug

A medication that has the same active ingredients as a brand-name drug but is usually sold at a lower price.

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Patient-Driven Care

Healthcare approach focusing on the patient's needs and preferences, ensuring their participation in treatment decisions.

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Medication Errors

Mistakes that occur during the prescribing, dispensing, or administering of medications.