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Pharmacology
The science of looking at the composition, effects, and uses of drugs.
Nursing Role in Pharmacologic Care
Nurses are responsible for understanding the effect of medications on the disease process, providing interventions, monitoring plans, and educating patients.
Safe Medication Administration
A set of principles to ensure proper patient care includes right patient, medication, route, dose, reason, time, assessment, documentation, education, and the right to refuse.
Medication Reconciliation
The process of comparing a patient's medication orders to all medications the patient is taking to prevent errors.
Controlled Substances Act
Federal legislation that regulates the manufacture, importation, possession, use, and distribution of certain substances.
Pharmacokinetics
The study of how the body processes a drug, covering absorption, distribution, metabolism, and excretion.
Half-Life
The time it takes for the concentration of a drug in the bloodstream to decrease by half.
Adverse Effects
Undesired effects of medications that can be harmful or cause complications.
Anticholinergic Effects
Effects resulting from the blockage of the parasympathetic nervous system, leading to symptoms like dry mouth and blurred vision.
Look-Alike/Sound-Alike Medications
Drug names that may be confused due to their similar appearance or pronunciation, increasing the risk of medication errors.
Peak and Trough Levels
Measurements of drug concentration in the blood; peak is the highest level after administration, while trough is the lowest level before the next dose.
Agonist
A substance that occupies and activates receptors to produce a desired effect.
Antagonist
A substance that occupies receptors but does not activate them, preventing agonists from exerting their effects.
Pharmacodynamics
The interaction between a drug and its target receptors or sites in the body.
CYP-450 System
A group of enzymes critical to the metabolism of drugs, affecting how drugs are processed by the body.
Off-Label Use
Use of a medication for an indication not approved by the FDA.
High Alert Medications
Medications that have a heightened risk of causing significant harm if used in error.
Patient Education Regarding Medications
Providing patients with vital information about their medications including uses, administration, and potential side effects.
Opioids
A class of drugs that include prescription pain relievers, known for their pain-relieving properties and high potential for addiction.
Efficacy
The ability of a drug to produce the desired therapeutic effect.
Therapeutic Index
The ratio between the toxic and therapeutic concentrations of a drug.
Biotransformation
The chemical modification made by an organism on a chemical compound.
Drug Interactions
The effect that occurs when two or more drugs react with each other, potentially altering their effects.
Polypharmacy
The concurrent use of multiple medications, which is particularly common in older populations.
Active Metabolites
Metabolites of a drug that have a pharmacological effect, potentially increasing the drug's efficacy or toxicity.
Generic Drug
A medication that has the same active ingredients as a brand-name drug but is usually sold at a lower price.
Patient-Driven Care
Healthcare approach focusing on the patient's needs and preferences, ensuring their participation in treatment decisions.
Medication Errors
Mistakes that occur during the prescribing, dispensing, or administering of medications.