Polyethylene Glycol 335 (Miralax)

Indication for Polyethylene Glycol 335 (Miralax)

Constipation

Mechanism of Action of Polyethylene Glycol 335 (Miralax)

Osmotic agent. Draws water into G.I. lumen.

Therapeutic effects of Polyethylene Glycol 335 (Miralax)

Evacuation of G.I. tract without water or electrolyte imbalance.

Pharmacokinetics of Polyethylene Glycol 335 (Miralax)

Nonabsorbed from G.I. tract and is excreted in feces.

Contraindications of Polyethylene Glycol 335 (Miralax)

• G.I. Obstruction

• Gastric retention

• Toxic colitis

• Megacolon

• Bowel perforation

In what situations should Polyethylene Glycol 335 (Miralax) be cautiously adminsitered?

ABD of uncertain cause, especially if accompanied by fever.

What should you assess a patient taking Polyethylene Glycol 335 (Miralax)?

Assess for the following:

• ABD distention

• Bowel sounds

• Pattern of bowel function

How would you assess the stool of a patient taking Polyethylene Glycol 335 (Miralax)?

• Color

• Consistency

• Quantity

What medications may be confused with Polyethylene Glycol 335 (Miralax)?

• Mirapex (Pramipexole)

• Propylene Glycol

What patient teaching points should be emphasized for patients taking Polyethylene Glycol 335 (Miralax)?

• Results may take 2-4 days of use

• Prolonged, frequent, or excessive use may cause elecrolyte imbalance and laxative dependence