Brain
"at a microscopic level it is the most dynamic organ of the body"
86
"The human brain contains roughly __ billion nerve cells"
Neurons
Nerves cells are also called
Through Synapses
How do neurons communicate with each other?
Neurons
Their collective activity monitors internal and external environments
Neurons
"creates all of our mental experiences, and controls all of our behavior"
central nervous system
"The brain and spinal cord (which extends from the brain down through the bones of the spinal column) make up the _________, which integrates and synthesizes neural information."
nerves
Extensions from the nervous system are called
nerves
make up the peripheral nervous system
neuron
a single cell in the nervous system
nerve
is a bundle of many neuronsâor, more precisely, a bundle consisting of the axons
nerves
connect the central nervous system to the bodyâs sensory organs, muscles, and glands
sensory neurons
bundled together to form nerves, carry information from sensory organs (including the eyes, ears, nose, tongue, and skin) into the central nervous system
motor neurons
also bundled into nerves, carry messages out from the central nervous system to operate muscles and glands.
interneurons
exist entirely within the central nervous system and carry messages from one set of neurons to another. Interneurons collect, organize, and integrate messages from various sources. They vastly outnumber the other two types.
cell body
the widest part of the neuron. It contains the cell nucleus and other basic machinery common to all bodily cells
Dendrites
are thin, tubelike extensions that branch extensively and function to receive input to the neuron
motor neurons and interneurons
In what neurons do the dendrites extend directly off the cell body and generally branch out from it, forming bushlike structures?
sensory neurons
In what neuron do dendrites branch out from one end of the axon, rather than directly from the cell body
axon
The ______ is another thin, tubelike extension from the cell body and its job is to carry messages to other neurons
axon terminal
each branch ends with a small swelling called an
Axon terminals
are designed to release chemical transmitter molecules onto other neurons or, in the case of motor neurons, onto muscle cells or glandular cells
myelin sheath
axons of some neurons are surrounded by a casing called a
glial cells
Myelin is a fatty substance produced by supportive brain cells called
action potentials
Neurons exert their influence on other neurons and muscle cells by firing off all-or-none impulses called
motor neurons and interneurons
"In which neurons are action potentials triggered at the junction between the cell body and the axon"
Sensory neurons
Which neurons are triggered at the dendritic end of the axon and travel through or past the cell body to the axon terminals
action potential
Which term when regarding chapter 4 is described as all or none because they either occur or donât
action potential
" Each of these produced by a given neuron is the same strength as any other produced by that neuron, and each retains its full strength all the way down the axon."
a neuron
"can varying degrees of intensity in its message by varying its rate of producing action potentials."
cell membrane
is a porous âskinâ that permits certain chemicals to flow into and out of the cell, while blocking others.
intracellular fluid
The tube is filled with a solution of water and dissolved chemicals called intracellular fluid
extracellular fluid
It is bathed on the outside by another solution of water and dissolved chemicals called
soluble protein molecules (Aâ)
have negative charges and exist only in the intracellular fluid
potassium ions (K+)
are more concentrated in the intracellular than the extracellular fluid
sodium ions (Na+) and chloride ions (Clâ)
are more concentrated in the extracellular than the intracellular fluid
â70 millivolt
This charge across the membrane of an inactive neuron is
resting potential
This charge across the membrane of an inactive neuron is called its
Action Potential
Is Elicited by a Brief Change in Membrane Permeability
action potential
is a wave of change in the electrical charge across the axon membrane
depolarization phase
The sudden shift constitutes which phase of the action potential
the repolarization phase
when enough positively charged potassium ions move out of the cell to reestablish the original resting potential. This constitutes which phase of the action potential
cellâs threshold
The axonâs membrane is constructed so that its sodium channels open in response to depolarization to some critical value; this triggers an action potential. This critical value (e.g., â65 millivolts inside, compared with a resting potential of â70 millivolts inside) is called the
axonâs diameter
The speed at which an action potential moves down an axon is affected by the
large diameter axons
present less resistance to the spread of electric currents and therefore conduct action potentials faster than thin ones
myelin sheath
A factor that speeds up the rate of conduction in many axons is the
myelin
What protects and insulates axons, speeding the rate at which nervous impulses can be sent and reducing interference from other neurons?
100 meters per second
The thickest and most thoroughly myelinated axons in the nervous system can conduct action potentials at a velocity of about
1 or 2 meters per second
Very thin axons without myelin sheaths, in contrast, may conduct at rates as slow as
myelination
"The process of developing myelin, called _________, begins before a child is born but is not complete until some time in adulthood, during the third decade of life or beyond."
sensory system
"Neurons in which system are the first to be myelinated"
associative areas
"The last areas to become fully myelinated are the __________ in the frontal cortexâthe âthinkingâ area of the brain"
synapse
The junction between each axon terminal and the cell body or dendrite of the receiving neuron is called a
neurotransmitter
When an action potential reaches an axon terminal, it causes the terminal to release packets of a chemical substance, called a
Neurotransmitters
are chemicals released by one neuron at the axon terminal to influence the action of an adjacent neuron
dopamine
"Influences movement and reward-motivated behavior"
acetylcholine
Is released at neuromuscular junction and associated with the activation of muscles.
acetylcholine
Within the brain, _______ functions to alter the way other brain structures process information "
serotonin
Influences many behaviors
serotonin
includes sleep, mood, and is implicated in depression
gamma-aminobutyric acid
As referred to as GABA
gamma-aminobutyric acid
"An inhibitory neurotransmitter, which weakens or slows down signals"
gamma-aminobutyric acid
plays an important role in anxiety
too much or too little
"Individuals who have___________ of some of these neurotransmitters may experience physical and psychological disorders."
Dopamine
Low levels of this neurotransmitter are associated with parkinsonâs disease
Schizophrenia
High levels of this neurotransmitter are associated with
synaptic cleft
"A very narrow gap, called the , separates the axon terminal from the membrane of the cell that it influences. "
presynaptic membrane
membrane of the axon terminal that abuts the cleft is the
postsynaptic membrane
that of the cell on the other side of the cleft is the
excitatory synapse
"At an ________ , the transmitter opens sodium (Na+) channels in the postsynaptic membrane."
inhibitory synapse
"At an ___________, the transmitter opens either chloride (Clâ) channels or potassium (K+) channels."
hyperpolarization
tends to decrease the rate of action potentials triggered in that neuron
depolarization, hyperpolarization
"At each excitatory synapse the transmitter causes a slight ______, and at each inhibitory synapse the transmitter causes a slight ______."
neurogenesis
"The process of creating new neurons is referred to as _________(literally, birth of neurons), and it occurs during the first 20 weeks after conception"
differentiation
"Beginning about 20 weeks after conception, neurons enter the last stage of their development, termed
differentiation
This doesnât stop at birth
losses of them
Beginning late in the prenatal period and continuing after birth, the primary changes in brain development are not in growth of neurons and synapses, but rather in
synapses
40 to 50% of these _______ will be lost, or pruned
apoptosis
neurons themselves also die in a process, known as selective cell death, or
mirror neurons
"Neuroscientists have discovered that the brains of human beings and of at least some nonhuman primates contain organized systems of neurons that seem to be well designed to foster social learning. These are referred to as ________ because they are believed to help us behave in ways that mirror (mimic) what we observe or experience."
Mirror Neurons
"are active both when a subject engages in a behavior, such as grasping a piece of food, and when the subject observes someone else perform a similar action."
mirror neurons
Are found in different parts of the monkey and human cerebral cortex
resting potential
is an electrical imbalance
analyzing electrical brain activity
EEGs, ERPs, MEG, TMS, tDCS are all used for
Electroencephalography (EEGs)
"Recording of the electrical activity of the cortex using multiple scalp electrodes."
Event Related Potentials (ERPs)
An encephalographic measure of local changes in the brain electrical activity in response to specific stimuli.
Magnetoencephalography
"Detects the magnetic field changes produced by the cortical electrical activity."
Transcranial Magnetic Stimulation (TMS)
The localization of a brain function by temporarily blocking the electrical activity of an area by exposure to a magnetic field
Transcranial Direct Current Stimulation (tDCS)
The localization of brain function by temporarily stimulating electrical activity directing weak electrical currents to specific areas of the brain
analyzing anatomical structure
MRIs and DTIs are used for
Magnetic Resonance Imaging (MRI)
High-resolution image of brain anatomy measuring energy changes of brain tissue after an exposure to a strong magnetic field
Diffusion Tension Imaging (DTI)
Measures the diffusion of water in the brain tissue, permitting the imaging of the white matter tracts
analyzing functional metabolic activity
PETs and fMRIs are used for
Positron Emission Tomography (PET)
Assesses the metabolic activity of glucose or oxygen in the brain by following the path of a radioactive tracer injected intravenously
Functional Magnetic Resonance Imaging (fMRI)
Assesses indirectly the metabolic activity of the brain through measuring the changes of the blood flow
TMS
"Although ___ is usually used to study the effects of temporary inactivation of a brain area, it can also be used to study the effects of temporary activation"
TMS
"___ can be used to produce a map showing the functional connections between specific areas within movement-control portions of the cerebral cortex and the muscles controlled by those areas."
transcranial direct current stimulation (tDCS)
" a technique called _________ involves directing weak electrical currents to specific areas of the brain; it has been found to alter perceptual, cognitive, and motor functioning."
EEG
" Patterns in the ___ can be used as an index of whether a person is highly aroused, or relaxed, or asleep and can be used to identify various stages of sleep."
positron emission tomography (PET)
The first of these neuroimaging methods (developed in the 1970s) was