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Franz Gall
proposed phrenology
Phrenology
the detailed study of the shape and size of the cranium as a supposed indication of character and mental abilities.
Neurons
a nerve cell; the basic building block of the nervous system
Cell body (soma)
the part of a neuron that contains the nucleus; the cell's life-support center
dendrite
the bushy, branching extensions of a neuron that receive and integrate messages, conducting impulses toward the cell body. branches off the cell body
axon
the neuron extension that passes messages through its branches to other neurons or to muscles or glands. passes messages through its terminal branches. extends off the dendrite.
myelin sheath
a fatty tissue layer segmentally encasing the axons of some neurons; enables vastly greater transmission speed as neural impulses hop from one node to the next. As the myelin sheath is laid down up to about age 25, neural efficiency, judgment, and self-control grow. If the myelin sheath degenerates, multiple sclerosis results.
multiple sclerosis
communication to muscles slows with eventual loss of muscle control.
glial cells
cells in the nervous system that support. nourish, and protect neurons; they also play a role in learning, thinking, and memory.
action potential
a neural impulse, a brief electrical charge that travels down the axon. a neuron sends a message by firing an impulse, "action potential". neuron stimulation causes the electrical charge to go above -55 mV, triggering the action potential.
the temporary inflow of positively charged ions - neural impulse
resting potential
positively charged sodium ions are in the fluid outside an axons membrane and large, negatively charged protein ions and smaller positively charged potassium ions in the fluid's interior (mostly negative)
Depolarization
the loss of the inside/outside charge difference. when a neuron fires, positively charged sodium ions (attracted to the negative interior) flow through the newly opened axon channels, causing the loss of the difference in charges. depolarization cases more axon channels to open.
excitatory neurotransmitters
like pushing a neuron's gas pedal; increases the likelihood of an action potential (Glutamate)
inhibatory neurotransmitters
chemicals released from the terminal buttons of a neuron that inhibit the next neuron from firing; like pushing the neuron's brake. decreases the likelihood of an action potential. GABA
threshold potential
-55mV
The minimum membrane potential must be reached in order for an action potential to be generated.
If the excitatory signals exceed the inhibitory signals by a minimum intensity, the combined signals trigger an action potential.
Refractory period
the time following an action potential during which a new action potential cannot be initiated. the neuron can't fire until after it returns to its resting state.
all or none response
a neuron's reaction of either firing (with a full-strength response) or not firing. increasing the level of stimulation above the threshold will not increase the intensity of the reaction. a strong stimulation can trigger more neurons to fire and to fore more often, but does not affect the action potential's strength and speed.
synapse
the gap between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron
neurotransmitters
chemical messengers that cross the synaptic gaps between neurons. when released by the sending neuron, neurotransmitters travel across the synapse and bind to the receptor sites on the receiving neuron.
unlocks channels at the receiving site and either excite or inhibit the receiving neuron.
reputake
When a sending neuron reabsorbs any leftover neurotransmitters to be reused. leftover neurotransmitters can also be broken down by enzymes.
Agonist molecules
increases neurotransmitter activity by:
unlocks channels at the receiving site and either excite or inhibit the receiving neuron.
blocking reuptake
-or be similar enough (mimics) to a neurotransmitter to bind to its excitatory/inhibitory effects
Antagonist molecules
Decreases a neurotransmitter's action by blocking production or release
-enough like natural neurotransmitters to occupy its receptor site and block its effect but not similar enough to stimulate receptor and produce effects
Acetylcholine
functions: memory, movement (muscle contraction), attention/arousal, learning
oversupply: muscle convulsions
Undersupply: memory loss (Alzheimer's) and paralysis
Dopamine
Functions: movement, pleasure/reward, learning, attention
Oversupply: schizophrenia (treated by antagonist drugs that block dopamine)
undersupply: Parkinson's disease (tremors/decreased mobility)
Serotonin
functions: mood, sleep, alertness, appetite, anxiety
undersupply: depression, sleep disorders, aggression
*anti depressants are agonists
Norepinephrine
functions: arousal/attention, neurotransmitter and hormone, sympathetic nervous system (activates fight or flight)
oversupply: anxiety, panic attacks, mania
undersupply: depression
*adrenal glands release this and epinephrine
GABA
functions: sleep, relaxation
undersupply: seizures, insomnia, anxiety disorders, Huntington's disease
*MAJOR INHIBATORY NUEROTRANSMITTER
Glutamate
functions: memory, learning
oversupply: migraines/seizures, possible CNS disease
*MAJOR EXCITATORY NEUROTRANSMITTER
endorphins
functions: inhibit pain (released in response to pain/vigorous exercise) and pleasure, can be either neurotransmitter or hormone
oversupply: higher pain threshold, runner's high
undersupply: lower pain threshold, lowered natural production due to use of opiates (results in withdrawal cravings)
neurotransmitters
*produced in CNS
hormones
*produced by pituitary/adrenal glands:
Nervous system
the body's electrochemical communication network consisting of all the nerve cells of the peripheral and central nervous system. RELEASES NEUROTRANSMITTERS VERY FAST!!
CNS (central nervous system)
the spinal cord and brain
spinal cord
two way information highway connecting the peripheral nervous system and the brain
PNS (peripheral nervous system)
the sensory and motor neurons that connect the CNS to the rest of the body. two divisions are autonomic and somatic
nerves
bundled axons that form neural cables connecting the central nervous system with muscles, glands, and sense organs
Motor neurons
Carry outgoing information from the brain and spinal cord to the muscles and glands (Exits CNS)
-Efferent
sensory neurons
neurons that carry incoming information from the body's tissues and sensory receptors to the brain and spinal cord (CNS). enters CNS.
-afferent
interneurons
neurons within the brain and spinal cord; they communicate internally and process information between the sensory input and motor output
somatic nervous system
PART OF PNS. controls the body's skeletal muscles. also called the skeletal nervous system. enables VOLUNTARY control of skeletal system.
autonomic nervous system
PART OF PNS. controls the glands and muscles of the internal organs (ex heart). two divisions are sympathetic and parasympathetic. INVOLUNTARY movement
parasympathetic nervous system
the division of the autonomic nervous system that calms the body, conserving its energy. deaccelerates heartbeat, lowers blood pressure, stimulates digestion, increases saliva production, processes waste
sympathetic nervous system
the division of the autonomic nervous system that arouses the body, mobilizing its energy in stressful situations. FIGHT OR FLIGHT. accelerates heartbeat, raised blood pressure, inhibits digestion, perspiration, pupils dilated, inhibits saliva
ascending neural fibers
send up sensory information
descending neural fibers
send back motor-control information
reflexes
simple, automatic responses to sensory stimuli, such as the knee-jerk response, involves singular sensory neuron and singular motor neuron
-simple reflexes occur only in the spinal cord before the information reaches the brain
endocrine system
the body's "slow" chemical communication system; a set of glands that SECRETE HORMONES into the bloodstream. slower than nervous system
hypothalamus
gland of endocrine system; brain region that controls the pituitary gland
pituitary gland
regulates growth hormones and oxytocin, and controls other endocrine glands.
thyroid gland
affects metabolism
Parathyroid
helps regulate the level of calcium in the blood
adrenal glands
secrete hormones (epinephrine and norepinephrine) that help arouse the body in times of stress. autonomic nervous system orders these glands.
pancreas
Regulates the level of sugar in the blood
testis
secretes male sex hormones
ovary
secretes female sex hormones
leison
tissue destruction
EEG (electroencephalogram)
An amplified recording of the waves of electrical activity that sweep across the brain's surface. These waves are measured by electrodes placed on the scalp.
-most commonly used for epilepsy and seizures, analyzes brain as a whole
MEG (magnetoencephalography)
measures magnetic fields from the brain's natural electrical activity
CT/CAT (computed tomography)
a series of X-RAY photographs of the brain taken from different angles and combined by computer to create an image that represents a slice through the brain. SHOWS STRUCTURE, can reveal brain damage.
PET (positron emission tomography) scan
a visual display of brain activity that detects where a radioactive form of glucose goes while the brain performs a given task. INJECTS GLUCOSE!!! SHOWS ACTIVITY!
MRI (magnetic resonance imaging)
a technique that uses magnetic fields and radio waves to produce computer-generated images of soft tissue. MRI scans show brain anatomy. more accurate than CT. again, SHOWS STRUCTURE
fMRI
same thing as MRI but shows BOTH FUNCTION AND STRUCTURE
shows structure
CT, MRI, fMRI
shows activity/function
EEG, MEG, PET, fMRI
Brainstem
the oldest part and central core of the brain, beginning where the spinal cord swells as it enters the skull; the brainstem is responsible for automatic survival functions
medulla
the base of the brainstem; controls heartbeat and breathing
pons
Sits above medulla and helps coordinate movement and controls sleep
thalamus
the brain's sensory switchboard, located on top of the brainstem; it directs messages to the sensory receiving areas in the cortex and transmits replies to the cerebellum and medulla
reticular formation
a nerve network in the brainstem that plays an important role in controlling arousal. helps control arousal and filters incoming stimulus -responsible for sleep-wake cycle (REM)
Cerebellum
the "little brain" at the rear of the brainstem; functions include processing sensory input and coordinating movement output and balance
limbic system
neural system located below the cerebral hemispheres; associated with emotions and drives
Amyglada
part of limbic system that plays key roles in fear, excitement, arousal, and aggression
Hypothaalmus
Responsible for thirst, hunger, sex drive, temperature, sleeping. helps govern endocrine system via pituitary gland, linked to emotion and reward
Hippocampus
helps process explicit (conscious) memories for storage. decreases in size/function as we get older.
synaptic vesicles
Tiny pouches or sacs in the axon terminals that contain chemicals called neurotransmitters.
anti depressants
block reuptake of serotonin so there is more serotonin neurotransmitters in the synapse.
Cerebral cortex
intricate fabric of interconnected neural cells covering the cerebral hemispheres; the body’s ultimate control/information processing center
frontal lobes
lies behind the forehead, involved in speaking, muscle movement, making plants and judgement
parietal lobe
lying at the top of the head towards the rear, receives sensory input for touch and body position
occipital lobe
back of the head, includes areas that receive information from the visual fields
temporal lobe
lies above the ears, includes auditory areas, each receiving information from the opposite ear
motor cortex
controls VOLUNTARY movement (rear of frontal lobe)
somatosensory (sensory) cortex
registers information from the skin senses and body movement (left hemisphere section receives input from the body’s right side)
auditory cortex
receives information from the ears (part of temporal lobe)
visual cortex
receives information from the eyes (in occipital lobe)
association areas
areas of the cerebral cortex that are not involved in primary motor/sensory functions; rather they are involved in higher mental functions such as learning, remembering, thinking, and speaking.
prefrontal cortex
forward part of the frontal lobe that enables judgement, PLANNING, and processing new memories
Brocca’s area
language center located in the left frontal lobe, involved in expressive language
wenicke’s area
language center located in the left temporal lobe, involved in receptive language
plasticity
our brain adjusting to new experiences. the brain changes, especially during childhood, by reorganizing after damage or by building new pathways based on experience
neurogenesis
producing new neurons in an attempt to self-repair (either this or plasticity)
corpus callosum
neural fibers connecting the two hemispheres of the brain and carrying messages between them
split brains
a condition resulting from surgery that isolates the brain’s two hemispheres by cutting the fibers (mainly those of the corpus callosum) connecting them
visual field
the right sides of both retinas gather information from the left side of what you are looking at, vice versa. in each eye, information from the left half of your field of vision goes to your right hemisphere, and information from the right half of your vision field goes to your left hemisphere
split brain vs intact brain
intact: information is transferred across the corpus callosum from both hemispheres of the brain
split: cross-transference does not occur
left hemisphere
speaking and language
brocca’s and wernicke’s (expressive and receptive language)
math calculations
making literal interpretations
controlling right side of body
right hemisphere
perpetual tasks
making inferences
modulating speech
visual perception
recognition of emotion
controlling left side of body
consciousness
our subjective awareness of ourselves and our environment
cognitive neuroscience
combines the study of brain activity with how we learn, think, remember, and perceive