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A comprehensive set of question-and-answer flashcards covering historical contributors to cell theory, major cell organelles, their structures, and functions.
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Who authored “Micrographia” and improved the early compound microscope?
Robert Hooke
Which scientist perfected the simple microscope (200–300×) and first observed living cells called “animalcules”?
Anton van Leeuwenhoek
Who disproved spontaneous generation by showing maggots come from fly eggs, not rotting meat?
Francesco Redi
Which botanist helped develop the first two tenets of cell theory and stated that all plants are made of cells?
Matthias Schleiden
Who worked with Schleiden to formulate the first two cell-theory tenets?
Theodor Schwann
What Latin word is the term “cell” derived from, and what does it mean?
“Cellula,” meaning small room or storeroom
What is the most prominent membrane-bound organelle that houses chromosomes?
The nucleus
Name the five structural parts of the nucleus.
Nuclear envelope, nuclear pores, chromatin, nucleolus, nucleoplasm
During which nuclear process is DNA duplicated before cell division?
DNA replication
Which organelle orchestrates the flow of genetic information known as the Central Dogma (DNA → RNA → Protein)?
The nucleus
What is the basic structural framework of the plasma membrane?
A semipermeable phospholipid bilayer with embedded proteins and cholesterol
List two key functions of the cell (plasma) membrane.
Selective transport of nutrients/wastes and maintenance of cell shape (with cytoskeleton support)
What rigid outer structure is present in plants, fungi, bacteria, and algae but absent in animal cells?
The cell wall
Name the three main layers of a typical plant cell wall.
Primary cell wall, middle lamella, secondary cell wall
Which polysaccharide is the main component of plant cell walls?
Cellulose
What is the cell wall of fungi primarily made of?
Chitin
What is the bacterial cell wall composed of?
Peptidoglycan
Which double-membrane organelle in plants contains chlorophyll for capturing sunlight?
Chloroplast
What are the stacked disc structures inside chloroplasts where light-dependent reactions occur?
Grana (stacks of thylakoids)
Which cycle in the chloroplast stroma fixes carbon dioxide into sugars?
The Calvin cycle
What double-membrane organelle is nicknamed the “powerhouse of the cell”?
Mitochondrion
What are the inner-membrane folds of mitochondria that increase surface area for ATP production?
Cristae
Name two key functions of mitochondria besides ATP production.
Regulating apoptosis/signaling and calcium homeostasis
Which ER type is studded with ribosomes and synthesizes secretory proteins?
Rough endoplasmic reticulum
Which ER type lacks ribosomes and synthesizes lipids and stores Ca²⁺?
Smooth endoplasmic reticulum
What membrane-bound vesicle contains hydrolytic enzymes to digest cellular debris?
Lysosome
What cytoskeletal filaments form hollow 24-nm tubes used in mitotic spindle formation?
Microtubules
What organelle serves as the primary microtubule-organizing center in animal cells?
Centrosome
What cylindrical structure, composed of nine microtubule triplets, helps organize spindles?
Centriole
Which large, membrane-bounded compartment in plant cells stores water, ions, and pigments and provides turgor pressure?
Central vacuole
Which organelle modifies, sorts, and ships proteins from the ER in stacked cisternae?
Golgi apparatus (Golgi bodies)
What organelle breaks down fatty acids and neutralizes hydrogen peroxide using catalase?
Peroxisome
What universal molecular machines translate mRNA into protein?
Ribosomes
What are the sizes of prokaryotic and eukaryotic ribosomes, respectively?
70S (50S + 30S) and 80S (60S + 40S)
Name the three major components of the cytoskeleton.
Microtubules, microfilaments (actin), intermediate filaments
Which motor protein moves cargo toward the plus end of microtubules (cell periphery)?
Kinesin
Which motor protein moves cargo toward the minus end of microtubules (near the nucleus)?
Dynein
Which motor protein interacts with actin filaments for muscle contraction and cytokinesis?
Myosin
What semi-liquid matrix fills the cell between plasma membrane and nucleus, embedding organelles?
Cytoplasm (cytosol + suspended components)
What term describes the total living content of a cell, including cytoplasm and nucleus?
Protoplasm
State the first two classic tenets of cell theory.
1) All living organisms are composed of one or more cells. 2) The cell is the basic unit of structure and function in living things.