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schizophrenia spectrum disorders
-includes schizophrenia, schizoactive disorder, delusional disorder, schozotypal disorder, brief psychotic disorder, schizophreniform disorder, and substance-induced psychotic disorder
-chronic, more severe disorder
-GOAL: RECOVERY
central theme of schizophrenia spectrum disorders
-PSYCHOSIS (universal symptom)
psychotic symptoms
-hallucinations
-delusions
-disorganized thoughts, speech, or behavior
emil kraepelin
first described disorder as “dementia praecox”
eugen bleuler
-determined the presence of several types of schizophrenia
where did the word schizophrenia come from?
greek words SKHIZO (split) and PHREN (mind)
-pieces of the mind aren’t fitting together
schizophrenia
-requires comprehensive, multidisciplinary tx
-severe deterioration of social and occupational functioning
of all mental illnesses, schizophrenia causes more…
-lengthy hospitalizations
-chaos in family life
-exorbitant costs to people and governments
-fears
(GOES HAND-IN-HAND W/ DEPRESSION)
epidemiology of schizophrenia
-lifetime prevalence: about 1%
-age of consent (usually late adolescence or early adulthood)
-gender differences (earlier diagnosis and poor prognosis in men)
-ethnic and cultural differences (racial groups have varying rates, but black men are more predisposed)
-familial differences (1st degree biologic relatives = 10x greater risk)
-if genetically predisposed, traumatic event can trigger outbreak of symptoms
biologic influences of schizophrenia
-neuroanatomic findings (enlarged lateral and third ventricles, total brain volume overall decreased)
-genetics (first-degree biologic relatives)
-neurodevelopment (early neurodevelopment may lead to dysfunction)
-neurotransmitters, pathways, receptors (excess DOPAMINE, serotonin, glutamate and GABA, NMDA)
psychosocial theories for schizophrenia
-childhood trauma
-sociocultural factors (downward drift hypothesis)
-stressful life events may be associated with exacerbation of symptoms and increased rates of relapse
downward drift hypothesis
poor social conditions seen as consequence of, rather than a cause of, schizophrenia
clinical course of schizophrenia
-prodromal period (can last a couple weeks to YEARS)
-acute illness period (active psychosis)
-stabilization period
-maintenance and recovery period (can last months to years)
-relapses
diagnostic criteria for schizophrenia
2 or more of the following must be present (one of the two symptoms must include one of the top three)
-delusions
-hallucinations
-disorganized speech
-disorganized or catatonic behavior
-negative symptoms
SYMPTOMS MUST CONTINUE FOR AT LEAST 6 MONTHS
positive symptoms (schizophrenia)
-delusions
-hallucinations
-SOMETHING THERE THAT SHOULDN’T BE (extra)
positive symptoms: DELUSIONS
-grandiose (famous, special powers/abilities, rich)
-nihilistic (feel like they don’t exist)
-persecutory (paranoid, spying, poisoning, someone after them)
-somatic (feel things in/on their body, chip in their brain)
positive symptoms: HALLUCINATIONS
-auditory (most common, first ask “what are you hearing?”)
-visual (bugs, figures, shadows, “what do you see?”)
-tactile (bugs crawling on them)
-gustatory
-olfactory
negative symptoms
-LESS THAN NORMAL FUNCTION
-alexithymia
-apathy
-avolition
-ambivalence
-anhedonia
-alogia
-anergia
alexithymia
inability to detect/express emotion
apathy
lack of interest
avolition
lack of motivation
ambivalence
difficulty making decisions
anhedonia
lack of pleasure in things they used to love
alogia
lack of speech fluency
anergia
lack of energy
echolalia
person copying you VERBATIM
circumstantiality
talking in a circle, answer eventually
loose associations
one thought leads to another, loosely related
tangentiality
tangent, never answer questions/point
flight of ideas
go from thought-to-thought (not related)
word salad
words mixed up, no meaning behind them (cat, house, pond)
neologisms
using made-up words
paranoia
someone’s out to get them, sense of impending doom
referential thinking
-aka: ideas of reference
-someone thinks that something irrelevant means something to them (sirens sounding specifically to warn them, etc)
autistic thinking/concrete thinking
black-and-white, cut dry thinking
verbigeration
repeat something over and over again
metonymic speech
use wrong word but it’s related to the topic
“eat my menu”
clang association
repeat similar sounding words, “I’m fine, line, dine, etc”
stilted language
“it’s great to meet you on September 3rd, on Thursday, in room 2131…” SUPER FORMAL AND DETAILED
pressured speech
talking extremely fast
aggression/agitation
occurs during psychosis
catatonia
extra movements
catatonic excitement
completely still
echopraxia
Pt doing exactly what you’re doing
regressed behavior
child-like behavior
stereotypy
stereotypical, repetitive movements
hypervigilance
in psychosis, think someone is going to hurt them
waxy flexibility
body parts stay stationary instead of bending/flexing