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How do B cells bind thymus-dependent antigens?
B cells bind antigens through their membrane immunoglobulin and take them up via receptor-mediated endocytosis.
What happens to the antigen after it's taken up by the B cell?
The antigen is processed and loaded onto MHC class II molecules, which display peptides to CD4 T cells.
What is required for B-cell activation by thymus-dependent antigens?
Interaction with CD4 T cells is required for B-cell activation.
How does the CD4 T cell activate the B cell?
If the T-cell receptor recognizes the MHC-peptide complex presented by the B cell, it triggers B-cell activation.
