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Synapses
small spaces between neurons that are important centers for the transmission of electrochemical messages
Neurotransmitters
the carriers of these messages are biological messenger molecules
Sensory receptors
gather information by detecting changes in the environment
Nucleus
is near the center of the cell body and has a conspicuous nucleolus
Dendrites
usually high branched, providing receptive surfaces to which processes from other neurons communicate
Unmyelinated axons
the smallest axons also have Schwann cells enclosure, but they do not wind around them, so they lack a myelin sheath
-appear grey
Myelinated axons
axons with a myelinated sheath
-appear white
Sensory neurons
afferent neurons- carry nerve impulses from peripheral body parts into the CNS
Interneurons
association or internuncial neurons- lie within CNS, are multipolar and form links between other neurons
Motor neurons
efferent neurons- are multipolar and carry nerve impulses out of the CNS to effectors
Accelerator neurons
increase muscular activities
Inhibitory neurons
decreases muscular activities
Astrocytes
star-shaped cells- provide support and hold structures together
Oligodendrocytes
form myelin in the CNS, can send out a number of processes so that one cell can provide myelin for many axons
Microglia
are small and have fewer processes than other neuroglial cells, help support neurons and phagocytize bacterial cells and cellular debris
Ependymal
cuboidal or columnar cells that may have cilia, form the inner lining of the central canals, covers the inside of the ventricles, help regulate the composition of cerebrospinal fluid within the ventricles
Chemically gated
ion channels are opened or closed by this reaction
Synaptic potentials
created by chemically gated ion channels enable one neuron to influence another
Potential difference
the difference in the electrical charge between the two regions
Membrane potential
the potential difference across the membrane
-measured in millivolts
Resting potential
the membrane potential of a resting neuron and has a value of - 70mV
Hyperpolarized
if the membrane potential becomes more negative
Depolarized
if the membrane potential becomes more positive
Repolarization
slower voltage-gated potassium channels open, potassium diffuses outward and the inside of the membrane becomes negative again
Nerve impulse
a series of action potentials along an axon
Refractory period
following passage of a nerve impulse, a threshold stimulus will not trigger another impulse on an axon
Absolute refractory period
lasts about 1/2500 of a second- the membrane is changing in sodium permeability and cannot be stimulated
Relative refractory period
when the membrane is reestablishing its resting potential- a threshold stimulus of high intensity may trigger an impulse
Saltatory conduction
myelinated nerve fibers have action potentials occurring only at the nodes of Ranvier- they appear to jump from node to node
Acetylcholine
stimulates skeletal muscle contractions
Monoamines
formed by modifying amino acids
Acetylcholinesterase
decomposes acetylcholine
Reuptake
other neurotransmitters are transported back into the synaptic knob of the presynaptic neuron
Monoamine oxidase
inactivates epinephrine and norepinephrine after reuptake
Enkephalins
consist of a chain of 5 amino acids. Synthesized during periods of painful stress.
Beta endorphin
found in the brain and cerebrospinal fluid
Substance P
consists of 11 amino acids and is widely distributed throughout the nervous system
Forebrain
prosencephalon
Midbrain
short section between the diencephalon and pons. -mesencephalon
Hindbrain
rhombencephalon
Frontal lobe
bordered posteriorly by a central sulcus and inferiorly by a lateral sulcus
Parietal lobe
separated from frontal lobe by central sulcus
Temporal lobe
separated from frontal and parietal lobes by lateral sulcus
Occipital lobe
separated from cerebellum by a shelflike extension of the dura mater called the tentorium cerebelli
Insula
island of Reil- located deep within central sulcus- separated from the frontal, parietal, and temporal lobes by a circular sulcus
may serve as a crossroads for translating sensory information into appropriate emotional responses- such as feeling disgust at the sight of something unpleasant
Primary motor areas
lie in precentral gyri of the frontal lobes; contain many large pyramidal cells
Reticulospinal and rubrospinal tracts
coordinate and control motor functions that maintain balance and posture- many of these pass into the basal ganglia
Broca's area
just anterior to the primary motor cortex and superior to the lateral sulcus, usually in the left hemisphere
Frontal eye lid
controls voluntary movements of the eyes and eyelids
General interpretive area
plays the primary role in complex thought processing- receives input from multiple sensory areas and consolidates the information which is then communicated to other brain areas
Corpus callosum
transfer sensory information from the nondominant to the general interpretative area of the dominant
Memory consolidation
the conversion of short-term memories into long-term memories
Long-term synaptic potentiation
frequent, nearly simultaneous, and repeated stimulation of the same neurons, primarily in the hippocampus, strengthens their synaptic connections
Infundibulum
a conical stalk behind the optic chiasma to which the pituitary gland is attached
Posterior pituitary gland
hangs from the floor of the hypothalamus
Mammillary bodies
two rounded structured behind infundibulum which serve as relay stations for olfactory pathways
Pineal gland
produces the hormone melatonin
Limbic system
composed of portions of the cerebral cortex in the medial parts of the frontal and parietal lobes connecting with the hypothalamus, thalamus, basal nuclei, and other deep nuclei
-guides a person into behavior that might increase the chance of survival
Brainstem
connects the brain to the spinal cord
Cerebral peduncles
include the corticospinal tracts and are the main motor pathways between the cerebrum and the lower parts of nervous system
Corpora quadrigemina
four nuclei on the superior surface of midbrain
Cerebral aqueduct
connects the third and fourth ventricle
Red nucleus
near the center of the midbrain and communicates with the cerebellum and with centers of the spinal cord
Pons
appears as a rounded bulge on underside of midbrain- separates the midbrain from the medulla oblongata
Medulla oblonglata
an enlarged continuation of the spinal cord, extending from the level of the foramen magnum to the pons
Nucleus gracilis and nucleus cuneatus
receives sensory impulses from fibers of the fasciculus gracilis and fasciculus cuneatus and pass them on to the thalamus or the cerebellum
Cardiac center
increases or decreases the heart rate
Vasomotor center
constrict blood vessels to raise blood pressure; dilates blood vessels to lower blood pressure
Respiratory center
acts with centers in the pons to regulate the rate, rhythm, and depth of breathing
Reticular formation
a complex network of nerve fibers associated with tiny islands of gray matter; extends from the superior portion of the spinal cord into the diencephalon; connects centers of the hypothalamus, basal nuclei, cerebellum, and cerebrum with fibers in all major ascending and descending tracts.
Cerebellum
a large mass of tissue located inferior to the occipital lobes of the cerebrum and posterior to the pons and medulla
Vermis
connects the two hemispheres at the midline
Arbor vitae
a cut into the cerebellum reveals a treelike pattern of white matter
Cerebellar peduncles
communicates with other parts of CNS by three pairs of nerve tracts
Cervical enlargement
a thickening in the neck region that supplies nerves to the upper limbs
Lumbar enlargement
a thickening in the lower back that gives off nerves to the lower limbs
Central canal
continuous with the ventricles of the brain- filled with CSF
Reflex arcs
carry out the simplest responses- reflexes
Reflex center
sensory neuron leads to several interneurons within the CNS
Spinal reflexes
reflexes whose arc passes through the spinal cord
Fasciculus gracilis and fasciculus cuneatus
posterior funiculi; carry sensory impulses from the skin, muscles, tendons, and joints to the brain - interpreted as sensations of touch, pressure, and body movements
Spinothalamic tracts
lateral and anterior tracts located in the lateral and anterior funiculi; impulses cross over in the spinal cord
Spinocerebellar tracts
posterior and anterior tracts lie near the surface of the lateral funiculi; fibers in posterior remain uncrossed; anterior fibers cross over in the medulla
Corticospinal tracts
lateral and anterior tracts occupy the lateral and anterior funiculi; most over lateral tract fivers cross over in medulla; some of anterior fibers cross over at various levels of spinal cord
Reticulospinal tracts
lateral tracts are in lateral funiculi, anterior and medial tracts are in the anterior funiculi; some fibers of lateral cross over
Rubrospinal tracts
pass through lateral funiculi; cross over in brain
Peripheral nerve
consists of connective tissue surrounding bundles of nerve fibers
Epineurium
the outermost layer
General somatic efferent fibers
motor impulses from CNS to skeletal muscles and stimulate them to contract
General visceral efferent fibers
motor impulses from CNS to various smooth muscles and glands associated with internal organs, causing certain muscles to contract or glands to secrete
General somatic afferent fibers
sensory impulses to CNS from receptors in skin and skeletal muscles
General visceral afferent fibers
sensory impulses to CNS from blood vessels and internal organs
Special somatic efferent fibers
motor impulses to the muscles used in chewing, swallowing, speaking, and forming facial expressions
Special visceral afferent fibers
sensory impulses to the brain from the taste and olfactory receptors
Special somatic afferent fibers
sensory impulses to the brain from the receptors of sight, hearing, and equilibrium
Ophthalmic division
impulses to the brain from surface of eye, tear gland, and skin of anterior scalp, forehead, and upper eyelid