small spaces between neurons that are important centers for the transmission of electrochemical messages
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Neurotransmitters
the carriers of these messages are biological messenger molecules
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Sensory receptors
gather information by detecting changes in the environment
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Nucleus
is near the center of the cell body and has a conspicuous nucleolus
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Dendrites
usually high branched, providing receptive surfaces to which processes from other neurons communicate
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Unmyelinated axons
the smallest axons also have Schwann cells enclosure, but they do not wind around them, so they lack a myelin sheath
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-appear grey
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Myelinated axons
axons with a myelinated sheath
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-appear white
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Sensory neurons
afferent neurons- carry nerve impulses from peripheral body parts into the CNS
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Interneurons
association or internuncial neurons- lie within CNS, are multipolar and form links between other neurons
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Motor neurons
efferent neurons- are multipolar and carry nerve impulses out of the CNS to effectors
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Accelerator neurons
increase muscular activities
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Inhibitory neurons
decreases muscular activities
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Astrocytes
star-shaped cells- provide support and hold structures together
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Oligodendrocytes
form myelin in the CNS, can send out a number of processes so that one cell can provide myelin for many axons
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Microglia
are small and have fewer processes than other neuroglial cells, help support neurons and phagocytize bacterial cells and cellular debris
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Ependymal
cuboidal or columnar cells that may have cilia, form the inner lining of the central canals, covers the inside of the ventricles, help regulate the composition of cerebrospinal fluid within the ventricles
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Chemically gated
ion channels are opened or closed by this reaction
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Synaptic potentials
created by chemically gated ion channels enable one neuron to influence another
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Potential difference
the difference in the electrical charge between the two regions
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Membrane potential
the potential difference across the membrane
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-measured in millivolts
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Resting potential
the membrane potential of a resting neuron and has a value of - 70mV
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Hyperpolarized
if the membrane potential becomes more negative
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Depolarized
if the membrane potential becomes more positive
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Repolarization
slower voltage-gated potassium channels open, potassium diffuses outward and the inside of the membrane becomes negative again
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Nerve impulse
a series of action potentials along an axon
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Refractory period
following passage of a nerve impulse, a threshold stimulus will not trigger another impulse on an axon
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Absolute refractory period
lasts about 1/2500 of a second- the membrane is changing in sodium permeability and cannot be stimulated
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Relative refractory period
when the membrane is reestablishing its resting potential- a threshold stimulus of high intensity may trigger an impulse
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Saltatory conduction
myelinated nerve fibers have action potentials occurring only at the nodes of Ranvier- they appear to jump from node to node
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Acetylcholine
stimulates skeletal muscle contractions
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Monoamines
formed by modifying amino acids
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Acetylcholinesterase
decomposes acetylcholine
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Reuptake
other neurotransmitters are transported back into the synaptic knob of the presynaptic neuron
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Monoamine oxidase
inactivates epinephrine and norepinephrine after reuptake
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Enkephalins
consist of a chain of 5 amino acids. Synthesized during periods of painful stress.
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Beta endorphin
found in the brain and cerebrospinal fluid
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Substance P
consists of 11 amino acids and is widely distributed throughout the nervous system
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Forebrain
prosencephalon
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Midbrain
short section between the diencephalon and pons. -mesencephalon
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Hindbrain
rhombencephalon
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Frontal lobe
bordered posteriorly by a central sulcus and inferiorly by a lateral sulcus
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Parietal lobe
separated from frontal lobe by central sulcus
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Temporal lobe
separated from frontal and parietal lobes by lateral sulcus
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Occipital lobe
separated from cerebellum by a shelflike extension of the dura mater called the tentorium cerebelli
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Insula
island of Reil- located deep within central sulcus- separated from the frontal, parietal, and temporal lobes by a circular sulcus
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1) may serve as a crossroads for translating sensory information into appropriate emotional responses- such as feeling disgust at the sight of something unpleasant
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Primary motor areas
lie in precentral gyri of the frontal lobes; contain many large pyramidal cells
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Reticulospinal and rubrospinal tracts
coordinate and control motor functions that maintain balance and posture- many of these pass into the basal ganglia
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Broca's area
just anterior to the primary motor cortex and superior to the lateral sulcus, usually in the left hemisphere
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Frontal eye lid
controls voluntary movements of the eyes and eyelids
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General interpretive area
plays the primary role in complex thought processing- receives input from multiple sensory areas and consolidates the information which is then communicated to other brain areas
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Corpus callosum
transfer sensory information from the nondominant to the general interpretative area of the dominant
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Memory consolidation
the conversion of short-term memories into long-term memories
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Long-term synaptic potentiation
frequent, nearly simultaneous, and repeated stimulation of the same neurons, primarily in the hippocampus, strengthens their synaptic connections
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Infundibulum
a conical stalk behind the optic chiasma to which the pituitary gland is attached
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Posterior pituitary gland
hangs from the floor of the hypothalamus
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Mammillary bodies
two rounded structured behind infundibulum which serve as relay stations for olfactory pathways
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Pineal gland
produces the hormone melatonin
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Limbic system
composed of portions of the cerebral cortex in the medial parts of the frontal and parietal lobes connecting with the hypothalamus, thalamus, basal nuclei, and other deep nuclei
\-guides a person into behavior that might increase the chance of survival
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Brainstem
connects the brain to the spinal cord
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Cerebral peduncles
include the corticospinal tracts and are the main motor pathways between the cerebrum and the lower parts of nervous system
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Corpora quadrigemina
four nuclei on the superior surface of midbrain
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Cerebral aqueduct
connects the third and fourth ventricle
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Red nucleus
near the center of the midbrain and communicates with the cerebellum and with centers of the spinal cord
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Pons
appears as a rounded bulge on underside of midbrain- separates the midbrain from the medulla oblongata
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Medulla oblonglata
an enlarged continuation of the spinal cord, extending from the level of the foramen magnum to the pons
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Nucleus gracilis and nucleus cuneatus
receives sensory impulses from fibers of the fasciculus gracilis and fasciculus cuneatus and pass them on to the thalamus or the cerebellum
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Cardiac center
increases or decreases the heart rate
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Vasomotor center
constrict blood vessels to raise blood pressure; dilates blood vessels to lower blood pressure
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Respiratory center
acts with centers in the pons to regulate the rate, rhythm, and depth of breathing
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Reticular formation
a complex network of nerve fibers associated with tiny islands of gray matter; extends from the superior portion of the spinal cord into the diencephalon; connects centers of the hypothalamus, basal nuclei, cerebellum, and cerebrum with fibers in all major ascending and descending tracts.
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Cerebellum
a large mass of tissue located inferior to the occipital lobes of the cerebrum and posterior to the pons and medulla
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Vermis
connects the two hemispheres at the midline
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Arbor vitae
a cut into the cerebellum reveals a treelike pattern of white matter
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Cerebellar peduncles
communicates with other parts of CNS by three pairs of nerve tracts
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Cervical enlargement
a thickening in the neck region that supplies nerves to the upper limbs
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Lumbar enlargement
a thickening in the lower back that gives off nerves to the lower limbs
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Central canal
continuous with the ventricles of the brain- filled with CSF
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Reflex arcs
carry out the simplest responses- reflexes
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Reflex center
sensory neuron leads to several interneurons within the CNS
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Spinal reflexes
reflexes whose arc passes through the spinal cord
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Fasciculus gracilis and fasciculus cuneatus
posterior funiculi; carry sensory impulses from the skin, muscles, tendons, and joints to the brain - interpreted as sensations of touch, pressure, and body movements
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Spinothalamic tracts
lateral and anterior tracts located in the lateral and anterior funiculi; impulses cross over in the spinal cord
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Spinocerebellar tracts
posterior and anterior tracts lie near the surface of the lateral funiculi; fibers in posterior remain uncrossed; anterior fibers cross over in the medulla
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Corticospinal tracts
lateral and anterior tracts occupy the lateral and anterior funiculi; most over lateral tract fivers cross over in medulla; some of anterior fibers cross over at various levels of spinal cord
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Reticulospinal tracts
lateral tracts are in lateral funiculi, anterior and medial tracts are in the anterior funiculi; some fibers of lateral cross over
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Rubrospinal tracts
pass through lateral funiculi; cross over in brain
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Peripheral nerve
consists of connective tissue surrounding bundles of nerve fibers
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Epineurium
the outermost layer
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General somatic efferent fibers
motor impulses from CNS to skeletal muscles and stimulate them to contract
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General visceral efferent fibers
motor impulses from CNS to various smooth muscles and glands associated with internal organs, causing certain muscles to contract or glands to secrete
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General somatic afferent fibers
sensory impulses to CNS from receptors in skin and skeletal muscles
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General visceral afferent fibers
sensory impulses to CNS from blood vessels and internal organs
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Special somatic efferent fibers
motor impulses to the muscles used in chewing, swallowing, speaking, and forming facial expressions
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Special visceral afferent fibers
sensory impulses to the brain from the taste and olfactory receptors
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Special somatic afferent fibers
sensory impulses to the brain from the receptors of sight, hearing, and equilibrium
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Ophthalmic division
impulses to the brain from surface of eye, tear gland, and skin of anterior scalp, forehead, and upper eyelid