10: Cell Signaling Conserved Modules and NO Signaling

Control of NO signaling by PDE5

Nuclear Hormone Receptor Signaling

Nuclear Hormone Receptor (NHR) Signaling

NHR ligands and activation mechanism

NHR – specific binding sequences on DNA

NHR – specific binding sequences on DNA

Hereditary Vitamin D resistant Rickets

Androgen Insensitivity Syndrome (AIS) non-functional androgen receptor

G-Protein Coupled Receptor (GPCR) signaling is mediated by heterotrimeric GTPases

GPCRs control vision, olfaction, emotions and more

Different mechanisms of GPCR activation

GPCR signaling cascade

GPCR signaling execute through secondary messengers

GPCR signaling via DAG and IP3

Conservation of structure and function in Protein Kinases

GPCR signaling via Ca2+

Calmodulin Kinase – a molecular memory device

Calmodulin Kinase – a molecular memory device

Calmodulin Kinase – a molecular memory device

GPCRs can associate with same effector leading to different results