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PICO
Problem
Intervention
Comparison
Outcome
How to use PubMed
Searching for scientific evidence
Search box for medical subject heading (MeSH database)
Developed by the National Center for Biotechnology Information (NCBI)
Part of the National Library of Medicine (NLM)
Contains 36+ millions citations from MEDLINE
Entrez system
Components of PubMed
Search box
MeSH database
Helps group terminology together to find relevant articles
Advanced search
MeSH tree
Move up the tree to broader term
Entry terms
Synonyms, alternative names
Example
Stannous fluoride = entry term
Tin fluorides = Official MeSH term
Boolean operators
And
Results contain entered search terms
Retrieve from both
Narrows search
Or
At least one of the terms
Broadens search
Not
Excludes term from search
Caution — may exclude relevant citations
Using multiple boolean operators
Use parentheses
(tooth erosion OR tooth wear) AND (stannous fluoride toothpaste) AND (sodium fluoride)…
Advanced search bar
Can use #2 AND #3 if want to search same term again
Must use # sign before number
Filter on the side
Filter text availability, article type, publication dates
Addition features
Check article types, language, age
Article type
Filters studies by level of evidence
If none found = clear all
Click on next level of evidence
Publication date
Filter to range of years or show additional features
PubMed Clinical queries
Answers clinical questions for professionals and students
Contains clinical study categories (therapy, diagnosis, etiology, prognosis)
→ Change scope to narrow