Neurotransmission

Dopamine

• Excitatory get things revved up and excited

• Responsible for pleasure & reward, cognition, emotional responses, movement

• Schizophrenics have high __.

Serotonin

• Inhibitory slow down the body processes

• Responsible for emotions, sexual behavior, temp, sleep, pain management

• Decreased __ = anxiety, depression

Norepinephrine

• Excitatory

• Responsible for learning, sleep, mood, memory, attention

• Too much = anxiety, depression, social withdrawal

• Trauma ↑ __ = trauma related disorders cause anxiety/depression

GABA

• Inhibitory

• Responsible for neuron development, ­↑ sleep

• Benzodiazepines enhance binding of __ to its receptors = ↓ anxiety, ­↑sleepiness

Glutamate

• Excitatory

• Responsible for regulating motor, affective (emotions) & cognitive function

• ↑ = R/F psychosis

• ↑ = neuro toxic = permanent damage

Acetylcholine

• Inhibitory and excitatory

• Responsible for sleep/wake cycle, muscle function

• Alzheimer’s pts = ↓ __

• Alzheimer’s drugs ↑­__

Reuptake

• Pre-synapse receptors reuptake. Neurotransmitters

• If reuptake is blocked, neurotransmitters hang out in synapse and are more likely to complete neurotransmission.

Deactivate (monoamine oxidate)

• Monoamine oxidate = enzyme that breaks down neurotransmitters

• If Monoamine oxidate is blocked (MAOI), neurotransmitters are less likely to be broken down.