Glycolisis

Step 1- reaction type glycolysis?

Phosphorylation

Step 1 starting material?

Glucose (6C)

What happens during step 1?

ATP is consumed

Step 1 - final product

Glucose 6-phosphate

Step 2- reaction type

Isomerization

Step 2- starting material

Glucose 6-phosphate

What happens during step 2?

rearrangement of molecules

Step 2- final product

Fructose 6-phosphate (isomer)

Step 3- reaction type

Phosphorylation

Step 3- starting material

Fructose 6-phosphate

what happens during step 3?

ATP is consumed

Step 3 final product

Fructose 1,6-biphosphate (6C)

Step 4 - reaction type

cleavage

step 4 starting material

fructose 1,6-biphosphate

step 4- final product

glyceraldehyde 3-phosphate (3C)

Dihydroxyacetone phosphate (DHAP, 3C)

Step 5- reaction type

Isomerization of DHAP

Step 5- final product

(2) glyceraldehyde 3-phosphate (3 C)

Step 6- reaction type

oxidation

Step 6- starting material

2 glyceraldehyde 3-phosphate (3C)

What happens in step 6 of glycolysis?

2 NAD+ reduced to 2 NADH

Pi is attached to each C1

step 6- final product

2 1,3 biphosphoglycerate (BPG, 3C)

Step 7- rxn type

ATP synthesis by substrate level phosphorylation

step 7- starting material

2 BPG

What happens during step 7?

the transfer of 1p from BPG to ADP

final product of step 7

(2) 3-phosphoglycerate (3C)

generates 2 ATP

Step 8- rxn type

isomerization

step 8 final product

(2) 2-phosphoglycerate (3C)

Step 9- rxn type

dehydration

What happens in step 9?

2 waters are removed

step 9- final product

(2) phosphoenolpyruvate (pep, 3C)

Step 10- rxn type

ATP synthesis by substrate level phosphorylation

What happens in step 10?

the transfer of 1P from PEP to ADP

Step 10- final product

2 pyruvate (3C)

what is the yield of glycolysis?

2 ATP consumed at energy investment phase (step 1+3)

4 ATP and 2NADH produced at energy generation phase (Step 6, 7,10)

What is the NET yield?

2 ATP and 2 NADH