Cell Signaling Flashcards

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Ligand

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28 Terms

1

Ligand

A molecule that binds to another molecule, resulting in the formation of a complex that can deliver a signal.

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2

Intercellular Signaling

Communication between cells.

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3

Receptor

Proteins on target cells that bind to ligands.

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4

Target Cells

Cells that are affected by chemical signals.

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5

Paracrine Signaling

A type of signaling where a cell targets nearby cells.

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6

Endocrine Signaling

A type of signaling where a cell targets distant cells through the bloodstream.

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7

Autocrine Signaling

A type of signaling where a cell targets itself.

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8

Direct Signaling Across Gap Junctions

Signaling between cells connected by gap junctions allowing small signaling molecules to diffuse.

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9

Neurotransmitters

Chemical signals released across synapses between nerve cells.

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10

Signal Transduction

The process by which an extracellular signal is converted to an intracellular signal.

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11

Phosphorylation

The addition of a phosphate group to a molecule, activating enzymes and signaling pathways.

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12

Feedback Loop

A process in biological systems where the output of a system regulates its activity.

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13

Negative Feedback Loop

A change in a given direction causes a change in the opposite direction to maintain stability.

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14

Positive Feedback Loop

A process where a change in a variable leads to an even greater change in the same direction.

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15

Hydrophobic Ligands

Ligands that can freely travel across the cell membrane and interact with internal receptors.

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16

Transmembrane Receptors

Cell surface receptors that span the plasma membrane and convert extracellular signals into intracellular responses.

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17

Secondary Messengers

Small molecules that propagate a signal after its initiation and spread it through the cytoplasm.

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18

Dimer

A chemical compound formed when two molecules join together.

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19

What is Paracrine Signaling?

A type of signaling where a cell targets nearby cells.

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20

What is Endocrine Signaling?

A type of signaling where a cell targets distant cells through the bloodstream.

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21

What is Autocrine Signaling?

A type of signaling where a cell targets itself.

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22

What is Direct Signaling Across Gap Junctions?

Signaling between cells connected by gap junctions allowing small signaling molecules to diffuse.

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23

What are Neurotransmitters?

Chemical signals released across synapses between nerve cells.

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24

What is the role of Ligands in cell signaling?

Ligands bind to receptors on target cells, initiating a signaling response.

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25

What are Target Cells?

Cells that are affected by chemical signals.

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26

How do Receptors function in signaling?

Receptors on target cells specifically bind to ligands to trigger a response.

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27

What is Signal Transduction?

The process by which an extracellular signal is converted to an intracellular signal.

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28

What is the significance of Secondary Messengers?

Secondary messengers propagate a signal after its initiation and spread it through the cytoplasm.

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