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Flashcards covering key concepts from Chapter 3 on drug action across the lifespan, focusing on pharmacological principles, high-risk groups, and key terms.
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Drug responses vary due to __.
Age, genetics (pharmacogenetics), body composition, disease states, diet & nutrition, polypharmacy.
__ is the safest dosing parameter, especially important for pediatrics and older adults.
Weight (kg)
A __ effect refers to improvement without the active drug being administered.
Placebo
Drug __ is a condition characterized by decreased response to a drug over time.
Tolerance
__ term refers to the ability of a substance to cause cancer.
Carcinogenicity
__ drugs are those that can cause abnormal fetal development.
Teratogenic
In older adults, it is a best practice to __ and go slow with medication administration.
Start low
Avoid administering __ to patients from infancy through adolescence due to Reye’s syndrome risk.
Salicylates (aspirin)
Peak level refers to the __ concentration of a drug in the blood.
Highest
__ are effective in monitoring drug levels to prevent toxicity.
Therapeutic Drug Monitoring