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Module 12
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Name the four things that impact Heart Rate
Autonomic NS, hormones, fitness, age
What is role of gap junctions
Action potential propagation between cells
What doesn’t DIRECTLY affect Heart Rate
Blood Pressure
Blood Pressure affects
Cardiac Output
Stroke Volume
Blood pumped from end diastole to end systole
Afterload
Resistance; pressure to push blood into aorta out to body
Preload
Heart stretches during maximum diastole
Contractility
How hard heart squeezes w/every beat
Cardiac Output
Amount of blood pumped over one minute
Heart rate (HR)
How fast heart beats
Lisa comes out of open heart surgery with an ejection fraction of 40% (normal 50 - 70 %). Predict what will happen to Lisa's heart rate as the body tries to maintain cardiac output.
Heart Rate increases
Normal ejection fraction percentage
50-70%
Lower ejection fraction means
Low Stroke Volume
What happens to Cardiac Output when you increase preload
Increase cardiac output due blood amount that enters heart increases (aka More EDV)
What happens to CO when you increase afterload
Decreased Cardiac Output due increased resistance to push blood out of heart
What happens when systemic blood vessel diameter decreases
Decreased CO due to increased peripheral resistance
What happens when contractility is increased
Increased CO due heart squeezing faster
What happens when systemic blood volume decreases
Decreased CO due decreased BV
Heart beats 100 bpm with 100ml EDV with 50ml ESV. What’s heart’s ejection fraction?
50%
Heart beats 100 bpm with 100ml EDV with 50ml ESV. What’s Cardiac Output?
5000ml/min (Divide 5000 by 1000 to get 5 L)
Narrow blood vessels means
Lower Stroke Volume
Ejection Fraction Percentage Formula
Stroke Volume/EDV
Cardiac Output formula
Heart Rate times Stroke Volume
The moderator band prevents ___
too much stretch
What does Hypervolemia (Increased blood volume) do to BLOOD PRESSURE
Increased Blood Pressure due increased blood volume
What does decreased vessel length do to blood pressure
Decreased blood pressure due decreased vessel length
What does Tachycardia (increased HR) do to blood pressure
Increased BP due increased HR
What does vasoconstriction do for blood pressure
increased BP due decreased vessel diameter
Vasoconstriction is regulated by
Autonomic nervous system
Explain Vasoconstriction
circulating blood must move through smaller area under higher pressures. reduced blood flow → resistance increased → higher BP
What does Hyper viscosity Syndrome do to BP
Increased BP due increased viscosity
Vasoconstriction INCREASES
vein’s blood pressure, blood flow AND return of blood to heart!