Leukemias and Lymphomas

This set of flashcards covers essential vocabulary and concepts related to acute and chronic leukemias as well as lymphomas, highlighting key definitions, symptoms, and treatment methods.

Acute

A type of disease characterized by abrupt onset and more severe symptoms.

Chronic

A type of disease characterized by gradual onset and less severe symptoms.

Acute Lymphoblastic Leukemia (ALL)

A leukemia where peak incidence is 2-4 years of age, with accumulation of leukemic lymphoblasts in bone marrow and blood.

Chemotherapy

A treatment consisting of two phases: induction of remission and maintenance of remission, often using cytotoxic agents.

Myeloid (granulocytic)

Refers to cells related to the bone marrow that produce granulocytes and are associated with types of leukemia.

Philadelphia chromosome

A cytogenetic abnormality present in more than 90% of Chronic Myelocytic Leukemia (CML) cases characterized by a translocation between chromosomes 9 and 22.

CAR-T therapy

A treatment that modifies the patient's T cells to recognize and attack cancer cells, used for various leukemias.

B lymphocytes

A type of white blood cell involved in the immune response; predominant in Chronic Lymphocytic Leukemia (CLL).

Reed-Sternberg Cell

A hallmark malignant transformed lymphocyte associated with Hodgkin's Lymphoma.

Bone Marrow Transplant

A procedure involving the aspiration and filtration of bone marrow from a donor, introduced into the recipient to restore normal blood cell production.