Drug Prototypes

Prototype Penicillin

Penicillin G

Prototype Penicillinase-resistant penicillin

Methicillin

Prototype Carbapenem

Imipenem

Prototype 1st Gen Cephalosporin

Cefazolin/Cephalexin

Prototype Tetracycline

Tetracycline

Prototype Aminoglycoside

Gentamicin

Prototype Macrolide

Erythromycin

Prototype Azole Antifungal

Ketoconazole

Prototype Echinocandin Antifungal

Caspofungin

Prototype Antimalarial

Chloroquine

Prototype Antiviral

Acyclovir

Prototype NRTI (Nucleoside Reverse Transcriptase Inhibitor)

Zidovudine

Prototype Fibrate

Clofibrate/Gemfibrozil

Prototype Bile acid-binding resin

Cholestyramine

Prototype HMG-CoA reductase inhibitor

Lovastatin

Prototype Biguanide

Metformin

Prototype PPI (Proton Pump Inhibitor)

Omeprazole

Prototype Loop Diuretic

Furosemide

Prototype Thiazide Diuretic

Hydrochlorothiazide

Prototype Antianginal vasodilator

Nitroglycerin

Prototype Group 1A antiarrhythmic

Quinidine/Procainamide

Prototype Group 3 antiarrhythmic

Sotalol/Bretylium/Amiodarone

Prototype Cardiac Glycoside

Digoxin

Prototype Group 4 CCB

Verapamil/Diltiazem

Prototype Dihydropyridine CCB

Nifedipine

Prototype ACE inhibitor

Captopril

Prototype ARB (Angiotensin AT1 Receptor Blocker)

Losartan

Prototype Long-acting amide local anesthetic

Bupivacaine

Prototype Glucocorticoid

Prednisone

Prototype Androgen Receptor Antagonist

Flutamide

Prototype Aromatase Inhibitor

Anastrazole

Prototype General Anesthetic

Halothane

Prototype Medium-duration amide local anesthetic

Lidocaine

Prototype NSAID

Aspirin

Prototype Oral Anticoagulant

Warfarin

Prototype Opioid Analgesic

Morphine

Prototype Benzodiazepine

Diazepam

Prototype Phenothiazine Antipsychotic

Chlorpromazine

Prototype Tricyclic Antidepressant

Imipramine

Prototype SSRI (Selective Serotonin Reuptake Inhibitor) antidepressant

Fluoxetine

Prototype Antimanic

Lithium

Prototype Ethanolamine antihistamine

Diphenhydramine

Prototype 1st Gen H1 blocker

Chlorpheniramine

Prototype H2 blocker

Cimetidine

Prototype 5-HT3 receptor blocker

Ondansetron

Prototype Adrenoceptor agonist

Epinephrine & Norepinephrine

Prototype Indirect-acting sympathomimetic

Tyramine

Prototype Psychostimulant & Anorexiant

Amphetamine

Prototype Alpha-blocker

Phenoxybenzamine

Prototype Alpha 1-selective blocker

Prazosin

Prototype B1 & B2 agonist catecholamine

Isoproterenol

Prototype Rapid-acting B2 agonist

Albuterol

Prototype Nonselective Beta blocker

Propranolol

Prototype CNS dopamine agonist

Bromocriptine

Prototype Ganglion Blocker

Hexamethonium

Prototype Nondepolarizing neuromuscular blocker

Tubocurarine

Prototype Depolarizing neuromuscular relaxant

Succinylcholine

Prototype Cholinomimetic

Acetylcholine

Prototype Muscarinic receptor partial agonist

Pilocarpine

Prototype Cholinoceptor blocker

Atropine

Prototype Synthetic Quaternary Nitrogen Carbamate (less CNS effect) Cholinesterase inhibitor

Neostigmine

Prototype Centrally-acting Antimuscarinic

Benztropine

Prototype Short-acting Acetylcholinesterase inhibitor

Edrophonium

Prototype Weak Opioid Agonist

Codeine

Prototype 2nd Gen Cephalosporin

Cefuroxime

Prototype 5-HT1D Agonist

Sumatriptan

Prototype Cyclic Lipopeptide (CLP)

Daptomycin

Prototype Centrally-acting muscle relaxant

Mephenesin

Prototype 2nd Gen Atypical Antipsychotic

Clozapine

Prototype Local Anesthetic

Procaine

Prototype Anticonvulsant

Phenytoin

Prototype Opioid Antagonist

Naloxone

Prototype Group 2 antiarrhythmic

Propranolol

Prototype Indoline Thiazide-like Diuretic

Indapamide

Prototype Synthetic Pentasaccharide Anticoagulant

Fondaparinux

Prototype Short-acting insulin

Regular human insulin

Prototype Meglitinide Insulin Secretagogue

Meglitinide

Prototype "sulide" COX-2 Inhibitor

NS-398 & Nimesulide

Prototype "coxib" COX-2 Inhibitor

DuP 697

Prototype Organophosphate

Parathion

Prototype Sulfonamide

Prontosil

(Brilliant Red, Azo dye prodrug)

Prototype Quinolone

Nalidixic acid