exam 4

Which step of HIV replication is specifically inhibited by protease inhibitors?

Assembly and release of the virus

Which of the following activities currently puts one at the greatest risk of contracting hepatitis C?

Intravenous drug habit

A 2 year-old boy presents at the emergency room with muscle weakness and increasing paralysis. A history reveals the boy received a flu shot about 8 weeks previously. Differential diagnosis should include the possibility of __________

Guillain-Barre syndrome

Varicella zoster virus establishes latency in __________.

Nerve cells

Which of the following is mismatched?

Salk vaccine - live attenuated polio vaccine

Agent responsible for smallpox?

Variola virus

Which of the following is not a component of Influenza virus?

Reverse transcriptase

Rhinoviruses are a major cause of _____

Upper respiratory tract infections

Disease due to which of the following viruses is least likely directly transmissible from person to person?

Rabies

Which of the following is blood-borne pathogen in the form of an enveloped RNA virus, and is also associated with liver cancer in humans?

Hepatitis C virus

Which of the following conditions in animals or humans is not caused by prions?

Rabies

Hepatitis D virus requires a co-infection with which other virus?

Hepatitis B virus

Which of the following conditions is not associated with a latent period following initial viral infection?

Viral conjunctivitis

Enveloped RNA virus causing bronchitis and pneumonia, where infection is especially dangerous in premature infants with under-developed lungs:

Respiratory syncytial virus

A naked capsid DNA virus which causes upper respiratory tract infections:

Adenovirus

Which of the following signs or symptoms is not associated with viral hepatitis?

Petechial rash

Which of the following viruses has a reservoir in wild birds?

West Nile virus

Cytopathic effects associated with papillomavirus:

Piling up of cells

Common name for a childhood disease which is generally self-limiting in children, but is notorious for causing birth defects when the mother becomes infected during pregnancy:

Mumps

Which of the following vaccines should never be given to a pregnant woman?

MMR vaccine

The nature of the agent which causes Bovine Spongiform Encephalopathy (BSE, or mad-cow disease) is a___.

Protein

Effective, long-term immunity-conferring vaccination is currently available for which of the following?

Measles

Which of the following viral infections are not associated with recurring disease later in life?

Mumps virus

Naked capsid DNA virus which causes conjunctivitis:

Adenovirus

Whether viral replication leads to budding of viral particles, or lysis of the host cell, largely depends on___.

The presence or absence of a viral envelope

Immunity conferred by influenza vaccine typically protects the patient by preventing which of the following steps of the viral cycle?

Attachment

A 25 year old man is bitten by a potentially rabid bat during a caving trip. What is the recommended procedure for the treatment of this individual?

A, B and C

A dental hygienist reports a painful rash with blistering on one of her fingers. This description is consistent with ____.

Herpetic whitlow

Which of the following is not commonly associated with cancer in humans?

Herpes simplex virus

Sub-acute sclerosing pan-encephalitis (SSPE) is a rare, delayed consequence of infection by the virus that causes which childhood disease?

Measles

Which of the following is commonly responsible for "hand, foot and mouth disease"?

Coxsackie A virus

The threshold CD4 T cell count, below which patients typically start seeing opportunistic infections associated with acquired immunodeficiency syndrome (in cells/mm3 of blood).

200

The influenza viral protein, hemagglutinin, is important for which step of viral reproduction?

Attachment to epithelial cells

Agent commonly implicated in inflammation of the heart or pericardial sac.

Coxsackievirus

A newspaper published an article about a cruiseship where about 400 passengers were, "struck down with a notorious winter vomiting bug". The agent causing their affliction was likely ____.

Norovirus

1. Influenza virus

2. Adenovirus

Enveloped virus

Influenza virus

1. Influenza virus

2. Adenovirus

DNA virus

Adenovirus

1. Influenza virus

2. Adenovirus

Fecal oral transmission

Adenovirus

1. Influenza virus

2. Adenovirus

Occasionally catastrophic pandemics

Influenza

1. Influenza virus

2. Adenovirus

Respiratory infections

Both

1. Measles

2. Mumps

complications may include encephalitis

Both

1. Measles

2. Mumps

Kopliks spots inside mouth

Measles

1. Measles

2. Mumps

Vaccine is live-attenuated

Both

1. Measles

2. Mumps

Traditional childhood disease

Both

1. Measles

2. Mumps

Fecal oral transmission

Neither

1. Cytomegalovirus

2. Epstein Barr virus

Herpes virus family

Both

1. Cytomegalovirus

2. Epstein Barr virus

Latency in T cells

Neither

1. Cytomegalovirus

2. Epstein Barr virus

Agent of infectious mononucleosis

Both

1. Cytomegalovirus

2. Epstein Barr virus

May lead to cancer

Epstein Barr virus

1. Cytomegalovirus

2. Epstein Barr virus

Latency can be a complication in organ transplantation

Cytomegalovirus

1. Human immunodeficiency virus

2. Hepatitis C virus

Retrovirus

HIV

1. Human immunodeficiency virus