PRAC 142 Top Drugs (ADRs, Contraindications, BBW, BEERS List)

Zocor (simvastatin); Lipitor (atorvastatin); Crestor (rosuvastatin)

No common ADRs

Contraindicated in: Active liver disease

No Black Box Warning

Not on BEERS List

Mevacor, Altoprev (lovastatin)

No common ADRs

Contraindicated in: Active liver disease, pregnancy/nursing

No Black Box Warning

Not on BEERS List

Zetia (ezetimibe); Vascepa (icosapent ethyl); Tradjenta (linagliptin); Januvia (sitagliptin)

No common ADRs

No contraindications

No Black Box Warning

Not on BEERS List

Tricor, Trilipix (fenofibrate)

No common ADRs

Contraindicated in: Biliary cirrhosis, gallbladder disease, hepatic disease, renal failure/dialysis, nursing

No Black Box Warning

Not on BEERS List

Prinivil, Zestril (lisinopril); Vasotec (enalapril); Lotensin (benazepril); Lotrel (amlodipine/benazepril)

No common ADRs

Contraindicated in: H/o angioedema, combo w/ a neprilysin inhibitor (sacubitril)

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Zestoretic (lisinopril/HCTZ)

No common ADRs

Contraindicated in: H/o angioedema, combo w/ a neprilysin inhibitor (sacubitril), anuria, sulfonamide allergy

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Cozaar (losartan); Benicar (olmesartan); Micardis (telmisartan)

No common ADRs

Contraindicated in: Use w/ aliskiren in pts w/ diabetes

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Diovan (valsartan)

Common ADRs: Dizziness

Contraindicated in: Use w/ aliskiren in pts w/ diabetes

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Avapro (irbesartan)

Common ADRs: Hyperkalemia (in T2DM)

Contraindicated in: Use w/ aliskiren in pts w/ diabetes

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Hyzaar (losartan/HCTZ); Diovan HCT (valsartan/HCTZ)

No common ADRs

Contraindicated in: Use w/ aliskiren in pts w/ diabetes, anuria, sulfonamide allergy

Black Box Warning: 2nd/3rd trimester in pregnancy = fetal toxicity

Not on BEERS List

Lopressor (metoprolol tartrate)

Common ADRs: Bradycardia

Contraindicated in: Severe bradycardia, severe hypotension, 2nd/3rd degree AV block, cardiogenic shock, overt cardiac failure, acute decompensated HF, sick sinus syndrome, severe peripheral arterial circulatory disorders

Black Box Warning: IHD: abrupt discontinuation may exacerbate condition

Not on BEERS List

Toprol XL (metoprolol succinate)

No common ADRs

Contraindicated in: Severe bradycardia, severe hypotension, 2nd/3rd degree AV block, cardiogenic shock, acute decompensated HF, sick sinus syndrome w/o a pacemaker

Black Box Warning: IHD: abrupt discontinuation may exacerbate condition

Not on BEERS List

Tenormin (atenolol)

Common ADRs: Cold extremities, dizziness, tiredness

Contraindicated in: Severe bradycardia, 2nd/3rd degree AV block, cardiogenic shock, overt cardiac failure, acute decompensated HF

Black Box Warning: CAD; abrupt discontinuation may exacerbate condition

Not on BEERS List

Bystolic (nebivolol)

No common ADRs

Contraindicated in: Severe bradycardia, 2nd/3rd degree AV block, cardiogenic shock, decompensated cardiac failure, sick sinus syndrome w/o a pacemaker, severe hepatic disease (Child Pugh Score C)

No Black Box Warning

Not on BEERS List

Coreg (carvedilol)

Common ADRs: Diarrhea, hypotension, bradycardia, dizziness

Contraindicated in: Asthma, 2nd/3rd degree AV block, severe bradycardia w/o a pacemaker, cardiogenic shock, acute decompensated HF, severe hepatic disease, sick sinus syndrome

No Black Box Warning

Not on BEERS List

Inderal (propranolol)

No common ADRs

Contraindicated in: Asthma, severe bradycardia, 2nd/3rd degree AV block, cardiogenic shock, acute decompensated HF, sick sinus syndrome w/o a pacemaker

Black Box Warning: Angina pectoris: abrupt discontinuation may exacerbate condition

Not on BEERS List

Normodyne, Trandate (labetalol)

Common ADRs: Dizziness

Contraindicated in: Asthma, HF, 2nd/3rd degree AV block, cardiogenic shock, severe bradycardia, severe and prolonged hypotension

No Black Box Warning

Not on BEERS List

Betapace, Sorine, Sotylize (sotalol)

Common ADRs: Dizziness, fatigue, HA (>240 mg), bradycardia

Contraindicated in: Asthma, severe bradycardia w/o a pacemaker, 2nd/3rd degree AV block, long QT syndrome, cardiogenic shock, decompensated HF, serum K+

Catapres, Catapres-TTS (clonidine)

Common ADRs: Somnolence, fatigue

No contraindications

No Black Box Warning

BEERS (avoid as 1st-line antihypertensive)

Apresoline (hydralazine)

No common ADRs

Contraindicated in: CAD, rheumatic heart disease

No Black Box Warning

Not on BEERS List

Norvasc (amlodipine)

Common ADRs: Edema

No contraindications

No Black Box Warning

Not on BEERS List

Procardia, Procardia XL (nifedipine)

Common ADRs: Flushing, dizziness, HA

Contraindicated in: Concomitant use w/ CYP inhibitors (rifampin), cardiogenic shock

No Black Box Warning

BEERS (IR only)

Cardizem LA, Tiazac (Diltiazem)

No common ADRs

Contraindicated in: 2nd/3rd degree AV block, severe hypotension, cardiogenic shock, sick sinus syndrome w/o a pacemaker, acute MI, pulmonary congestion

No Black Box Warning

BEERS (Avoid in symptomatic HF)

Microzide (HCTZ); Thalitone (chlorthalidone); Demadex (torsemide)

No common ADRs

Contraindicated in: Anuria, sulfonamide/sulfonylurea allergy

No Black Box Warning

Not on BEERS List

Maxzide, Dyazide (triamterene/HCTZ)

No common ADRs

Contraindicated in: Hyperkalemia, concomitant K+ altering agents, impaired renal f(x), sulfonamide allergy

Black Box Warning: Hyperkalemia

Not on BEERS List

Lasix (furosemide)

No common ADRs

Contraindicated in: Anuria

No Black Box Warning

Not on BEERS List

Bumex (bumetanide)

No common ADRs

Contraindicated in: Anuria, hepatic encephalopathy, electrolyte imbalance

Black Box Warning: Potent diuretic (too much = profound diuresis w/ H2O and electrolyte loss)

Not on BEERS List

Entresto (sacubitril/valsartan)

Common ADRs: Hypotension

Contraindicated in: H/o angioedema, concomitant use w/ ACEi, do not use w/in 36 hrs of switching to or from ACEi, avoid use w/ aliskiren in pts w/ diabetes

Black Box Warning: Fetal toxicity (avoid in pregnancy)

Not on BEERS List

Glucophage, Glucophage XR (metformin)

Common ADRs: Farts, N/V/D

Contraindicated in: Severe renal impairment, metabolic acidosis, DKA

Black Box Warning: Lactic acidosis

Not on BEERS List

Jardiance (empagliflozin)

No common ADRs

Contraindicated in: Severe renal impairment (ESRD and dialysis)

No Black Box Warning

Not on BEERS List

Trulicity (dulaglutide)

Common ADRs: N/V/D

Contraindicated in: Thyroid C-cell tumors, MTC, MEN 2

Black Box Warning: Risk of thyroid C-cell tumors

Not on BEERS List

Ozempic, Wegovy, Rybelsus (semaglutide)

Common ADRs: N/V/D, constipation, tummy pain

Contraindicated in: H/o MTC, MEN2

Black Box Warning: Risk of thyroid C-cell tumors

Not on BEERS List

Amaryl (glimepiride)

Common ADRs: Hypoglycemia

Contraindicated in: DKA, sulfonamide allergy

No Black Box Warning

BEERS (increased risk of CV events, mortality, and hypoglycemia)

Glucotrol, Glucotrol XL (glipizide)

No common ADRs:

Contraindicated in: DKA, sulfonamide allergy

No Black Box Warning

BEERS (increased risk of CV events, mortality, and hypoglycemia)

Novolog (insulin aspart); Humalog (insulin lispro)

Common ADRs: Hypoglycemia

Contraindicated in: Hypoglycemia

No Black Box Warning

BEERS (if used on sliding scale w/o concurrent use of basal/long-acting insulin)

Lantus (insulin glargine); Levemir (insulin detemir)

Common ADRs: Hypoglycemia

Contraindicated in: Hypoglycemia

No Black Box Warning

Not on BEERS List

Tylenol #2, 3, 4 (APAP/codeine)

No common ADRs

Contraindicated in: Children

Norco, Vicodin (APAP/hydrocodone)

No common ADRs

Contraindicated in: Status asthmaticus, respiratory depression, GI obstruction

Black Box Warning: Addiction/abuse/misuse, REMS, respiratory depression, accidental ingestion, neonatal opioid withdrawal syndrome, concurrent use of 3A4 inducers/inhibitors and benzos, hepatotoxicity, death related to ultra rapid metabolism in children

BEERS (if h/o falls/fracture, delirium)

Percocet (APAP/oxycodone HCl)

No common ADRs

Contraindicated in: Status asthmaticus, respiratory depression, GI obstruction

Black Box Warning: Addiction/abuse/misuse, REMS, respiratory depression, accidental ingestion, neonatal opioid withdrawal syndrome, concurrent use of 3A4 inducers/inhibitors and benzos, hepatotoxicity

BEERS (if h/o falls/fracture, delirium)

Oxycontin (oxycodone CR)

Common ADRs: N/V, constipation, somnolence, pruritis

Contraindicated in: Status asthmaticus, respiratory depression, GI obstruction

Black Box Warning: Addiction/abuse/misuse, respiratory depression, accidental ingestion, neonatal opioid withdrawal syndrome, concurrent use of 3A4 inducers/inhibitors, concurrent use w/ BZD or CNS depressants

BEERS (if h/o falls/fracture, delirium)

Duramorph, MS Contin (morphine)

No common ADRs

Contraindicated in: Status asthmaticus, respiratory depression, GI obstruction, MAOI therapy in

Ultram, Ultram ER (tramadol, tramadol ER)

Common ADRs: N/V/D, somnolence, dizziness, constipation, dry mouth, flushing, HA, pruritis, insomnia, asthenia

Contraindicated in: Status asthmaticus, respiratory depression, GI obstruction, children

Mobic (meloxicam)

No common ADRs

Contraindicated in: Tx of peri-op pain in CABG

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, and bleeding

BEERS

Motrin, Advil (ibuprofen)

No common ADRs

Contraindicated in: Tx of peri-op pain in CABG

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, and bleeding

BEERS

Aleve, Naprosyn (naproxen)

No common ADRs

Contraindicated in: Tx of peri-op pain in CABG

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, and bleeding

BEERS

Voltaren XR (diclofenac sodium ER)

No common ADRs

Contraindicated in: Tx of peri-op pain in CABG

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, and bleeding

BEERS

Toradol (ketorolac)

No common ADRs

Contraindicated in: Active or hx of PUD, GI bleed/perforation, pre-op pain management, tx of peri-op pain in CABG, advanced renal impairment, hypovolemia, labor and delivery, high risk bleeders, CV bleed, hemorrhage diathesis, incomplete hemostasis, intracranial bleed, concurrent ASA, NSAID, probenecid, and pentoxyfilline use

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, bleeding, tx >5 days, pediatrics, not used for minor or chronic pain, advanced risk for: renal impairment, bleeding, labor and delivery, concurrent NSAID use, geriatrics, pts

Celebrex (celecoxib)

No common ADRs

Contraindicated in: Sulfonamide allergy, tx of peri-op pain in CABG

Black Box Warning: CV risk (MI, stroke), GI perforation, ulceration, and bleeding

BEERS (if h/o HF)

Flexeril (cyclobenzaprine)

Common ADRs: Drowsiness, dry mouth

Contraindicated in: Acute recovery phase of MI, QT prolongation, arrhythmia, heart block, CHF, hyperthyroidism, MAOI therapy in

Lioresal (baclofen)

Common ADRs: Drowsiness

No contraindications

No Black Box Warning

Not on BEERS

Robaxin (methocarbamol)

No common ADRs

No contraindications

No Black Box Warning

BEERS

Xanax (alprazolam)

Common ADRs: Drowsiness, fatigue, impaired coordination, dysarthria, memory impairment, cognitive disorder, constipation, increased appetite, weight gain or loss, depression, lightheadedness; HA, confusion, insomnia, dry mouth, N/V, tachycardia, palpitations, irritability, decreased libido

Contraindicated in: Concurrent use w/ strong CYP3A4 inhibitors

Black Box Warning: Concurrent use w/ opioids, abuse/misuse/addiction, dependence and withdrawal reactions

BEERS

Ativan (lorazepam)

No common ADRs

Contraindicated in: Acute, narrow-angle glaucoma

Black Box Warning: Concurrent use w/ opioids, abuse/misuse/addiction, dependence and withdrawal reactions

BEERS

Valium (diazepam)

No common ADRs

Contraindicated in: Myasthenia gravis, severe respiratory and hepatic insufficiency, sleep apnea, acute narrow-angle glaucoma

Black Box Warning: Concurrent use w/ opioids, abuse/misuse/addiction, dependence and withdrawal reactions

BEERS

Klonopin (clonazepam)

Common ADRs: Somnolence, dizziness, upper respiratory tract infection

Contraindicated in: Significant hepatic disease, acute narrow-angle glaucoma

Black Box Warning: Concurrent use w/ opioids, abuse/misuse/addiction, dependence and withdrawal reactions

BEERS

Restoril (temazepam)

No common ADRs

Contraindicated in: Pregnancy

Black Box Warning: Concurrent use w/ opioids, abuse/misuse/addiction, dependence and withdrawal reactions

BEERS

Ambien, Ambien CR, Intermezzo (zolpidem)

Common ADRs: Dizziness, somnolence

Contraindicated in: Complex sleep behaviors

Black Box Warning: Complex sleep behaviors (ex. sleep-walking

BEERS

Plavix (clopidogrel)

No common ADRs

Contraindicated in: Active bleed

Black Box Warning: Diminished effectiveness in poor metabolizers (CYP2C19)

Not on BEERS List

Coumadin, Jantoven (warfarin)

No common ADRs

Contraindicated in: Unsupervised pts w/ conditions associated w/ potential high level of non-compliance, bleeding, aortic dissection, aneurysm, hemorrhagic stroke, head trauma, pregnancy, bacterial endocarditis, malignant HTN, regional or lumbar block anesthesia, surgery, pericarditis, pericardial effusion, active ulceration or overt bleeding of GI, genitourinary, or respiratory tract

Black Box Warning: Bleeding risk

BEERS (avoid for nonvalvular AFib or VTE)

Xarelto (rivaroxaban)

No common ADRs

Contraindicated in: Bleeding

Black Box Warning: Premature D/C increases risk of thrombotic events, epidural/spinal hematomas w/ neuraxial anesthesia or spinal puncture

BEERS (Avoid for long-term tx of nonvalvular AFib or VTE)

Eliquis (apixaban)

No common ADRs

Contraindicated in: Bleeding

Black Box Warning: Premature D/C increases risk of thrombotic events, epidural/spinal hematomas w/ neuraxial anesthesia or spinal puncture

Not on BEERS List

Digox, Lanoxin (digoxin)

No common ADRs

Contraindicated in: VFib

No Black Box Warning

BEERS (avoid as 1st-line for HF and AFib; if used for AFib or HF, avoid doses >0.125 mg/day)

Pacerone (amiodarone)

No common ADRs

Contraindicated in: AV block, 2nd/3rd degree AV block unless a pacemaker is available, cardiogenic shock, sick sinus syndrome, iodine allergy

Black Box Warning: Pulmonary toxicity, hepatotoxicity, cardiac toxicity, proarrhythmic

BEERS (avoid as 1st-line for AFib unless pt has HF or substantial LVH)

Tambocor (flecainide acetate)

Common ADRs: Dizziness, visual disturbances, dyspnea

Contraindicated in: AV block, 2nd/3rd degree AV block unless a pacemaker is available, cardiogenic shock

No Black Box Warning

Not on BEERS List

Nitrostat (nitroglycerin SL)

No common ADRs

Contraindicated in: Increased ICP, concomitant PDE-5 inhibitors, concomitant riociguat use, severe anemia, circulatory failure/shock

No Black Box Warning

Not on BEERS List

Monoket, Imdur (isosorbide mononitrate)

No common ADRs

Contraindicated in: Concomitant PDE-5 inhibitors, concomitant riociguat use

No Black Box Warning

Not on BEERS List

Ranexa (ranolazine)

No common ADRs

Contraindicated in: Strong CYP3A4 inhibitors and inducers, liver cirrhosis

No Black Box Warning

Not on BEERS List

Calan, Veralan (verapamil)

No common ADRs

Contraindicated in: Severe LVD, sick sinus syndrome, AFlutter/AFib w/ accessory bypass tract, 2nd/3rd degree AV block unless a pacemaker is available, hypotension (

Amantine (midodrone)

Common ADRs: Paresthesia, piloerection, dysuria, pruritis

Contraindicated in: Severe organ heart disease, acute renal disease, urinary retention, pheochromocytoma, thyrotoxicosis, persistent and excessive supine HTN

Black Box Warning: Marked/persistent elevation of supine BP

Not on BEERS List

Prilosec (omeprazole); Nexium (esomeprazole magnesium); Dexilant (dexlansoprazole); Protonix (pantoprazole)

No common ADRs

Contraindicated in: Concomitant ripilvirine-containing products

No Black Box Warning

BEERS (if used >8 weeks unless high risk)

Pepcid (famotidine)

No common ADRs

No contraindications

No Black Box Warning

BEERS (with delirium)

Celexa (citalopram)

No common ADRs

Contraindicated in: MAO-I use or w/in 14 days after D/C, concomitant pimozide, linezolid, methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (with h/o falls/fractures)

Lexapro (escitalopram)

Common ADRs: Diarrhea, nausea, HA, ejaculation disorder, insomnia, somnolence

Contraindicated in: MAO-I use or w/in 14 days after D/C, concomitant pimozide, linezolid, methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (with h/o falls/fractures)

Prozac (fluoxetine)

Common ADRs: Asthenia, nausea, anorexia, anxiety, insomnia, tremor, somnolence, dyspepsia, dry mouth, diarrhea, nervousness, decreased libido, pharyngitis, HA, flu syndrome

Contraindicated in: Fluoxetine use w/in 14 days of D/C MAO-I, MAO-I use w/in 5 weeks of D/C fluoxetine, concomitant pimozide, linezolid, thioridazine, and methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (with h/o falls/fractures)

Zoloft (sertraline)

Common ADRs: Nausea, diarrhea, dry mouth, somnolence, insomnia

Contraindicated in: MAO-I use or w/in 14 days after D/C, concomitant pimozide, linezolid, methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (with h/o falls/fractures)

Paxil (paroxetine)

Common ADRs: Asthenia, nausea, somnolence, dizziness, insomnia, sexual dysfunction, dry mouth, sweating, constipation, HA

Contraindicated in: MAO-I use or w/in 14 days after D/C, concomitant pimozide, thioridazine, linezolid, IV methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS

Cymbalta (duloxetine)

Common ADRs: Nausea, dry mouth, somnolence

Contraindicated in: MAO-I use w/in 5 days of D/C med, use w/in 14 days of D/C MAO-I, concomitant linezolid and IV methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (w/ h/o falls/fractures)

Effexor, Effexor XR (venlafaxine)

Common ADRs: Nausea, dry mouth, dizziness, insomnia, somnolence, sweating, constipation, abnormal ejaculation

Contraindicated in: MAO-I use or w/in 7 days of D/C med, use w/in 14 days of D/C MAO-I, concomitant linezolid and methylene blue use

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (w/ h/o falls/fractures)

Elavil (amitriptyline)

No common ADRs

Contraindicated in: MAO-I use w/in 14 days after D/C, concurrent cisapride use, use during acute recovery phase following MI

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS

Pamelor (nortriptyline)

No common ADRs:

Contraindicated in: MAOIs use concurrently or w/in 14 days of stopping treatment, use during the acute recovery period after MI

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS

Silenor (doxepin)

No common ADRs

Contraindicated in: MAOIs use concurrently or w/in 14 days of stopping treatment, untreated narrow angle glaucoma, severe urinary retention

Black Box Warning: Increased risk of suicidality in children, adolescents, and young adults

BEERS (for doses >6 mg/day)

Wellbutrin, Wellbutrin SR, Wellbutrin XL (bupropion)

No common ADRs

Contraindicated in: Seizure disorder, bulimia, anorexia nervosa, abrupt D/C of alcohol, BZDs, barbiturates, antiepileptics, MAOI therapy in

Remeron (mirtazapine)

Common ADRs: Somnolence, increased appetite, weight gain, dry mouth, constipation

Contraindicated in: MAOI therapy in

Buspar (buspirone)

Common ADRs: Dizziness

Contraindicated in: MAOI therapy in

Abilify (aripriprazole)

Common ADRs: Vomiting, insomnia, fatigue, somnolence, akathisia

No absolute contraindications

Black Box Warning: Increased mortality in dementia-related psychosis, suicidal ideation w/ antidepressant use

BEERS

Zyprexa (olanzapine)

Common ADRs: Constipation, somnolence, dizziness, asthenia, dry mouth, dyspepsia, EPS, increased appetite, weight gain, HA

No absolute contraindications

Black Box Warning: Increased mortality in dementia-related psychosis

BEERS

Seroquel, Seroquel XR (quetiapine)

Common ADRs: Somnolence, dizziness, dry mouth, constipation, asthenia, increased appetite, fatigue, HA, tachycardia

No absolute contraindications

Black Box Warning: Increased mortality in dementia-related psychosis, suicidal ideation w/ antidepressant use

BEERS

Risperidal (risperidone)

Common ADRs: Sedation, Parkinsonism, akathisia, EPS, insomnia, anxiety, dizziness, N/V

Contraindicated in: Paliperidone allergy

Black Box Warning: Increased mortality in dementia-related psychosis

BEERS

Depakote, Depakote ER, Depakote Sprinkles (divalproex sodium/valproic acid)

Common ADRs: N/V/D, HA, diplopia, asthenia, somnolence, dizziness, accidental injury, tremor, abdominal pain, anorexia, respiratory infection, thrombocytopenia, alopecia

Contraindicated in: Hepatic dysfunction, mitochondrial disease, urea cycle disorders, pregnancy

Black Box Warning: Hepatotoxicity, fetal risk, pancreatitis

BEERS (w/ h/o falls/fractures)

Neurontin, Gralise, Horizant (gabapentin)

Common ADRs: Fatigue, somnolence, dizziness, ataxia

No absolute contraindications

No Black Box Warning

BEERS (w/ h/o falls/fractures, increased risk of overdose w/ concomitant use of opioids)

Lyrica (pregabalin)

Common ADRs: Blurred vision, dry mouth, constipation, weight gain, dizziness, somnolence, peripheral edema, infection, accidental injury, ataxia, tremor, diplopia, fatigue

No absolute contraindications

No Black Box Warning

BEERS (w/ h/o falls/fractures, increased risk of overdose w/ concomitant use of opioids)

Lamictal (lamotrigine)

Common ADRs: N/V, HA, rhinitis, dizziness, ataxia, somnolence, rash, diplopia, blurred vision, abdominal pain, tremor

No absolute contraindications

Black Box Warning: Serious skin rash

BEERS (w/ h/o falls/fractures)

Keppra, Keppra XR (levetiracetam)

Common ADRs: Asthenia, infection, somnolence, fatigue, aggression, irritability, nasopharyngitis, vomiting

No absolute contraindications

No Black Box Warning

BEERS (w/ h/o falls/fractures)

Topamax (topiramate)

Common ADRs: Dizziness, ataxia, speech disorder, paresthesia, somnolence, difficulty w/ memory, confusion, diplopia, nervousness, psychomotor, slowing, diarrhea, taste disturbance, abnormal vision, fatigue, nausea, abdominal pain, URTI

No absolute contraindications

No Black Box Warning

BEERS (w/ h/o falls/fractures)

Mysoline (primidone)

No common ADRs

Contraindicated in: Patients w/ porphyria

No Black Box Warning

BEERS

Aricept (donepezil)

Common ADRs: Nausea, diarrhea, insomnia

Contraindicated in: Piperidine derivative allergy

No Black Box Warning

BEERS (w/ h/o syncope)

Valtrex (valacyclovir)

Common ADRs: HA, abdominal pain, decreased neutrophil count

No absolute contraindications

No Black Box Warning

Not on BEERS List

Namenda (memantine); Zovirax (acyclovir); Keflex (cephalexin); Penicillin VK; Amoxil (amoxicillin); Oracea, Vibramycin, Doryx (doxycycline); Bactroban (mupirocin); Mycostatin (nystatin); Plaquenil (hydroxychloroquine sulfate); Zyloprim, Aloprim (allopurinol); Myrbetriq (mirabegron); Carafate (sucralfate); Xalatan (latanoprost)

No common ADRs

No absolute contraindications

No Black Box Warning

Not on BEERS List

Omnicef (cefdinir)

Common ADRs: Diarrhea

No absolute contraindications

No Black Box Warning

Not on BEERS List

Augmentin (amoxicillin/clavulanic acid)

No common ADRs

Contraindicated in: Patients with h/o cholestatic jaundice/hepatic dysfunction associated w/ Augmentin

No Black Box Warning

Not on BEERS List