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Isomers
Compounds with the same molecular formula but different structural arrangements.
Catabolism
Breaking polymers into monomers; releases energy.
Anabolism
Building monomers into polymers; requires energy.
Osmosis
Movement of water across a selectively permeable membrane.
Facilitated diffusion
Passive transport that uses membrane transport proteins and does not require ATP.
Active transport
Movement of substances against a concentration gradient using ATP.
Hypertonic solution
A solution that causes a cell to lose water and shrink.
Hypotonic solution
A solution that causes a cell to gain water and swell.
Isotonic solution
A solution with no net water movement into or out of the cell.
Epithelial tissue
Avascular tissue that covers surfaces, lines cavities, and forms glands.
Polarity of epithelium
Epithelial tissue has an apical surface and a basal surface.
Connective tissue fibers
The three major fibers are collagen, elastic, and reticular fibers.
Chondroitin sulfate
A component of cartilage matrix/ground substance.
Stratum basale
The deepest layer of the epidermis.
Stratum corneum
The most superficial layer of the epidermis.
Merocrine glands
Sweat glands that produce watery sweat for thermoregulation.
Sebaceous glands
Glands that secrete sebum to lubricate skin and hair.
Apocrine glands
Glands found mainly in axillary and anogenital regions that produce a thicker secretion.
Osteoblasts
Bone-forming cells.
Osteoclasts
Bone-resorbing cells.
Osteocytes
Mature bone cells that maintain bone tissue.
Diaphysis
The shaft of a long bone.
Epiphysis
The end of a long bone.
Metaphysis
The region between the diaphysis and epiphysis; contains the growth plate in growing bones.
Axial skeleton
Skull, vertebral column, and thoracic cage.
Appendicular skeleton
Limbs and the pectoral and pelvic girdles.
Synovial joint
A freely movable joint with a joint cavity and articular cartilage.
Sarcomere
The functional contractile unit of skeletal muscle.
Epimysium
Connective tissue surrounding the entire muscle.
Perimysium
Connective tissue surrounding a fascicle.
Endomysium
Connective tissue surrounding an individual muscle fiber.
Neuromuscular junction
The synapse between a motor neuron and a muscle fiber.
ACh at NMJ
Acetylcholine is the neurotransmitter released at the neuromuscular junction.
Troponin
The protein that binds calcium during muscle contraction.
Tropomyosin
A regulatory protein that blocks myosin-binding sites on actin when the muscle is relaxed.
Sliding filament theory
The mechanism of contraction in which actin filaments slide past myosin filaments to shorten the sarcomere.
Twitch
A brief contraction of muscle fibers in response to one action potential.
Incomplete tetanus
Repeated stimulation with partial relaxation between contractions.
Complete tetanus
Sustained contraction with no relaxation between stimuli.
Concentric contraction
A contraction in which the muscle shortens while producing force.
Eccentric contraction
A contraction in which the muscle lengthens while producing force.
Isometric contraction
A contraction in which tension develops without a change in muscle length.
Resting membrane potential
The polarized state of a cell membrane due to ion gradients and selective permeability.
Graded potential
A local potential that varies in size and can summate.
Action potential
An all-or-none electrical signal that propagates without decreasing in strength.
Phrenic nerve
The nerve that primarily innervates the diaphragm.
Sciatic nerve
A major nerve that innervates much of the lower limb.
Cerebrospinal fluid
Cushions the CNS and helps with nutrient delivery and waste removal.
Primary motor cortex
The brain region in the frontal lobe responsible for voluntary motor control.
Primary somatosensory cortex
The brain region in the parietal lobe responsible for receiving sensory input.
Sympathetic nervous system
The fight-or-flight division of the autonomic nervous system.
Parasympathetic nervous system
The rest-and-digest division of the autonomic nervous system.
Endocrine glands
Glands that secrete hormones directly into the bloodstream.
Exocrine glands
Glands that secrete products into ducts or onto epithelial surfaces.
Hematocrit
The percentage of blood volume made up of red blood cells.
Erythropoietin (EPO)
A hormone that stimulates red blood cell production in bone marrow.
Albumin
The main plasma protein responsible for maintaining blood osmotic pressure.
Globulins
Plasma proteins involved in transport and immune functions.
Fibrinogen
A plasma protein important in blood clot formation.
Anemia
A condition in which the oxygen-carrying capacity of blood is reduced.
Pernicious anemia
Anemia caused by lack of intrinsic factor leading to poor vitamin B12 absorption.
Iron deficiency anemia
Anemia caused by inadequate iron for hemoglobin synthesis.
Thalassemia
Anemia caused by reduced or abnormal hemoglobin chain production.
Hemorrhagic anemia
Anemia caused by blood loss.
Hemolytic anemia
Anemia caused by red blood cell destruction.
Agglutination
Clumping of red blood cells caused by antigen-antibody reactions.
Type A blood
Blood type with A antigens on red blood cells and anti-B antibodies in plasma.
Type B blood
Blood type with B antigens on red blood cells and anti-A antibodies in plasma.
Type AB blood
Blood type with both A and B antigens and no anti-A or anti-B antibodies.
Type O blood
Blood type with no A or B antigens and both anti-A and anti-B antibodies in plasma.
Rh positive
Blood that has the Rh antigen present on red blood cells.
Rh negative
Blood that lacks the Rh antigen on red blood cells.
Universal donor
O negative.
Universal recipient
AB positive.
Neutrophils
The most abundant white blood cells; first responders that phagocytize bacteria.
Eosinophils
White blood cells involved in allergies and defense against parasitic worms.
Basophils
White blood cells that release histamine and heparin.
Lymphocytes
White blood cells including B cells, T cells, and NK cells involved in immune defense.
Monocytes
White blood cells that become macrophages in tissues.
B cells
Lymphocytes responsible for humoral immunity and antibody production.
T helper cells
CD4 positive cells that coordinate and activate other immune cells.
T cytotoxic cells
CD8 positive cells that kill infected or abnormal cells.
NK cells
Natural killer cells that destroy infected or cancerous cells without prior sensitization.
MHC I
Major histocompatibility complex class I found on all nucleated cells; presents to CD8 cells.
MHC II
Major histocompatibility complex class II found on antigen-presenting cells; presents to CD4 cells.
First line of defense
Skin and mucous membranes.
Innate immunity
Nonspecific defense present at birth.
Adaptive immunity
Specific defense with memory involving B and T lymphocytes.
Vaccination
Artificial stimulation of adaptive immunity that promotes memory cell formation.
Tunica intima
The innermost layer of a blood vessel.
Tunica media
The middle layer of a blood vessel made mainly of smooth muscle.
Tunica externa
The outer connective tissue layer of a blood vessel.
Blood hydrostatic pressure
Pressure that pushes fluid out of capillaries.
Blood colloid osmotic pressure
Pressure created mainly by plasma proteins that pulls fluid into capillaries.
Cardiac output
The volume of blood pumped by each ventricle per minute; CO = HR x SV.
Stroke volume
The amount of blood pumped by a ventricle with each beat; SV = EDV - ESV.
End-diastolic volume
The amount of blood in a ventricle at the end of filling.
End-systolic volume
The amount of blood left in a ventricle after contraction.
Mean arterial pressure (MAP)
Approximate average arterial pressure; MAP = DBP + 1/3 pulse pressure.
P wave
Atrial depolarization on the ECG.