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blood
red liquid that circulates in the arteries and veins of humans and other vertebrate animals
transportation
carries oxygen and CO2 to and from the tissue of the body
characteristics of blood
they are always red in color
the brighter the color, the more oxygen
veins are depicted as blue and red to indicate lower and higher oxygen levels
primary function
maintain homeostasis of pH, temperature, osmotic pressure
transports hormones, nutrients, gases
blood composition
circulatory system focuses on how these circulate through our bodies
plasma
erythrocytes and cells
platelets
plasma
liquid portion
lipids, salt, proteins, water
erythrocytes and cells
hemoglobin
RBC transports gases
WBC fights infection
hemoglobin
iron rich protein in our RBC that makes it red
platelets
helps with clotting (like when we scrape our knee)
arteries
carry blood away from the heart
typically oxygen rich, there are some exceptions though
different in pulmonary circulation*
veins
carry blood back to the heart
typically oxygen poor
VERB = veins efficiently return blood
different in pulmonary circulation*
pulmonary circulation
pulmonary arteries carry oxygen poor blood
pulmonary veins carry oxygen rich blood
capillaries
the site of gas exchange for oxygen and CO2
tiny blood vessels where oxygen is delivered to organs and tissues, while CO2 transports back to the lungs
overview of the heart
*study the diagram
right and left sides are flipped
A = atrium
V = ventricle
sometimes due to congenital heart conditions, deoxygenated and oxygenated blood tend to mix together
4 chambers
atrium
have thin walls
ventricle
have thick walls
“right side” of the heart
deoxygenated blood side
where blood gets circulated into the lungs and returns to the left side
“left side” of the heart
oxygenated blood side
4 chambers of the heart
A comes before V in the alphabet (A on top of V)
right atrium
right ventricle
left atrium
left ventricle
heart valves
help prevent blood from flowing backward
like one way doors separate chambers and prevent blood from flowing backwards
blood flow of deoxygenated blood to lungs
superior vena cava/ inferior vena cava → right atrium → tricuspid valve → right ventricle → pulmonic valve → pulmonary artery → lungs
ex: the blood in our fingertips is deoxygenated and needs to go all the way back to the heart, through this process, to the lungs
superior vena cava
collects blood from upper half of body
head
neck
upper limbs
upper torso
inferior vena cava
collects blood from the lower half of the body
legs
back
abdomen
pelvis
blood flow of oxygenated blood to tissues
lungs → pulmonary vein → left atrium → bicuspid/ mitral valve → left ventricle → aortic valve → aorta
aorta
major artery that carries oxygenated blood to all parts of the body, ensuring all organs have O2 to function
coronary arteries
check diagram
originate from the aorta and delivers nutrients and oxygen to the heart
coronary veins
check diagram
deoxygenated blood returns to the right atrium from the coronary sinus
septal defects
various conditions can disrupt the heart’s normal function, like altering the flow of blood within the heart
blood is going to be mixed between deoxygenated and oxygenated blood
occurs when the septum have some kind of abnormality
involves the opening that allows oxygen rich and poor blood to mix depending on the defect size, the mixing can lead to significant issues including abnormal heart rhythms, stroke, and heart failure
treatment includes medications to help manage the symptoms and surgical interventions
septum
muscular wall that divides the heart’s left and right sides
function: separate oxygen rich blood from oxygen poor blood between the chambers
interatrial septum
thin, muscular structure that consists of two parts: fossa ovalis and the limbus of the fossa ovalis
separate the right and left atria
disorder: atrial septal defect (ASD)
atrial septal defect (ASD)
a congenital heart defect where there is an abnormal opening in the interatrial septum, allowing blood to flow between the two atria
interventricular septum
thick, muscular wall that consists of two-parts: a membranous and muscular portion
separate the right and left ventricles
disorder: ventricular septal defect (VSD)
ventricular septal defect (VSD)
a congenital defect characterized by one or more holes in the interventricular septum, allowing blood to mix between the ventricles
electrical conduction system of the heart
study diagram
sinoatrial node
bachmann bundle
internodal pathway
fibrous tissue
atrioventricular node
sinoatrial node (SA)
main pacemaker
start electrical impulse
triggers atrial contraction
60-100 BPM
bachmann bundle
transmit high speed signal from SA node → left atrium
internodal pathways
anterior, middle, posterior
signal from SA node → AV node
fibrous tissue
found in septum
is important because it separates the left and right sides of the heart, including the atria and ventricles and hinders direct electrical signal transmission between these heart sections
atrioventricular node (AV)
secondary pacemaker
delay signal from SA node, which is crucial because it provides sufficient time for the atria to thoroughly contract
allows atria to contract to fill ventricles before ventricles can contract
40 to 60 BPM
bundle of his
only route between atria and ventricles
group of high speed transmission cells from the AV node, through the right atrium, then into the interventricular septum, where it branches off into the left and right ventricles
note: in individuals without cardiac abnormalities, these pathways represent the sole communication channel between the atrium and ventricles
right bundle branch
signal to right ventricle
left bundle branch
signal to left ventricle
purkinje fibers
last-ditch pacemaker
connect with myocytes
initialize depolarization, triggering a contraction
ventricular myocytes receive and further transmit those electrical signas to adjacent cells at a slower pace compared to the rapid transmission observed in the high speed bundle branches
20 to 40 BPM
bundle from both right and left bundle branches
note: the system has its own inherit pacemaker capability of its various cells, which govern the heart rate
study table
ECG basics
isoelectric line (baseline)
P wave
QRS complex
T wave
look at example
P wave
atrial depolarization (contraction)
QRS complex
ventricular depolarization (contraction)
normal QRS range: 0.06 to 0.12 seconds
atrial repolarization occurs during this, more important because ventricle contracts more forcefully
note: QRS complex looks like an inverted V, V stands for ventricles
T wave
ventricular repolarization (relaxation)
depolarization
contraction
repolarization
relaxation
systolic pressure
contraction of the heart “LUB” sound
top number on reading peak pressure in arteries
lower than 120
a high number could mean heart is too forceful ex: hypertension
diastolic pressure
relaxation of the heart “DUB” sound
bottom number on reading lowest pressure in arteries
lower than 80
high number could mean narrow arteries or too stiff increasing risk for heart disease