ASSAY OF SODIUM BICARBONATE, RM

Standardized Hydrochloric Acid

Sodium Bicarbonate RM

Methyl Red TS

Reagents of assay of sodium bicarbonate, RM

HCl (acid)

was used to neutralize sodium bicarbonate (base) to complete the neutralization reaction producing a product which is salt and water.

pH 4.2 = yellow

pH 6.2 = orange

pKa = 5.1

Methy red ph and pKa

NaHCO3 + HCl —> NaCl + CO2 + H2O

Chemical reaction of Assay of sodium bicarbonate

Methyl red

It is the indicator of choice for the Assay of Sodium Bicarbonate according to USP.

Baking soda

Other name of sodium bicarboante

NaHCO3

A white solid that is crystalline but often appears as a fine powder.

NaHCO3

Slightly alkaline (bitter) taste.

NaHCO3

the monosodium salt of carbonic acid with alkalinizing and electrolyte replacement properties.

USP= nlt 99% - nmt 105%

Sodium bicarbonate USP requirements

NaHCO3

used to relieve heartburn, acid indigestion by neutralizing excess stomach acid.

NaHCO3

treat the symptoms of stomach or duodenal ulcers.

NaHCO3

make the blood and urine more alkaline in certain conditions.

NaHCO3

treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.

NaHCO3

Excipient especially in effervescent preparations.

NaHCO3

Ingredient in non-fluoride toothpastes.

leavening agent in food.

pH regulator

used in tarnish-removing cleansers

used in dry, chemical-based fire extinguishers

purifier and catalyst in complex polymer and plastics

Give the industrial use of sodium bicarbonate

Mouthwash

Teeth whitener

Deodorant

Fridge odor neutralizer

Air freshener

Whitening agent for laundry

Kitchen cleaner

Carpet stain remover

Silverware polisher

Household use of Sodium bicarbonate

Hydrochloric acid

is a monoprotic strong acid -this means it dissociates completely in water.

Hydrochloric acid

is ideal as an acid titrant, and in general, it is inert to oxidation and reduction.

Sulfuric acid

nonvolatile but does form insoluble salts with alkaline earth hydroxides.