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Characteristics?
ADH, also known as vasopressin
• Peptide
• Activates vasopressin receptors
Physiological effects?
• Kidneys/renal: water reabsorption from collecting ducts
• Blood vessels: arteriole vasoconstriction (when ADH levels are very high)
• Overall: increased blood pressure (BP), increased fluid volume,
decreased urination
Target tissues?
Kidneys
Blood vessels
Stimulates release?
High blood osmolarity
• Low blood pressure (hypotension) / low blood
volume (hypovolemia)
• Angiotensin II
Inhibits release?
Low blood osmolarity
• High blood pressure (hypertension) / high blood
volume (hypervolemia)
• Alcohol
Additional information?
Levels peak overnight
• Medical conditions
• Low ADH diabetes insipidus
• High ADH syndrome of inappropriate ADH secretion (SIADH)