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Narcan
opioid antagonists
highly affinity
treat opioid overdose
very effective
crosses the BBB (blood brain barrier)
Naltrexone
opioid antagonists
used in management of opioid dependence
help over come opioid addiction
have little effect on opioid craving
Buprenorphine
opioid partial agents
high affinity
low intrinsic (less potent)
control craving
can produce typical opioid agonist effects
Suboxone
opioid partial agent
contain a combination of buprenorphine and naloxone (4:1)
not used as a pain medication
used to treat opioid use disorder (OUD)
Methadone maintenance
opioid agonist
slow onset
long acting agonist
provides moderate and controlled opioid experiences
might not work for everyone
prevent withdrawal symptoms/craving