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stem cells
where it all starts; cells with the potential to develop into many different types of cells in the body
omnipotent/totipotent
cells that are able to develop into any type of cell found in the body; has the potential to divide until it creates an entire, complete organism
pluripotent
have the ability to undergo self-renewal and to give rise to all cells of the tissues of the body; can divide into most, or all, cell types in an organism, but cannot develop into an entire organism on their own
multipotent
the ability to differentiate into multiple cell types, but only a limited number of closely related lineages
oligopotent
describes the condition of being more specialized than multipotency; the condition of being able to differentiate into one of a few possible cell types
unipotent
describes the condition of being committed to a single specialized cell type
cell; tissue; organ; organ system; organism
levels of organization
longitudinal section
cut through the long axis of an organ
cross section
the intersection of a solid and a plane
oblique section
cuts made diagonally between the horizontal and the vertical planes
transverse plane
horizontal division of the body into upper and lower portions
sagittal plane
vertical division of the body into right and left portions
frontal section
divides the body into anterior and posterior parts
ventral
toward the front or belly
dorsal
toward the back or spine
anterior
toward the ventral side
posterior
toward the dorsal side
cephalic
toward the head or superior end
rostral
toward the forehead or nose
caudal
toward the tail or inferior end
superior
above
inferior
below
medial
toward the median plane
lateral
away from the median plane
proximal
closer to the point of attachment or origin
distal
farther from the point of attachment or origin
ipsilateral
on the same of side of the body (right or left)
contralateral
on the opposite sides of the body (right and left)
superficial
closer to the body surface
deep
farther from the body surface
axial regions
consists of the head, neck (cervical), and trunk
trunk
consists of the thoracic and abdominal regions
hypochondriac region; epigastric region; subcostal line; lumbar region; umbilical region; intertubercular line; inguinal region; midclavicular line; hypogastric region
nine regions of the abdomen
hypochondriac region
to the right and left of the epigastric region above the subcostal line
epigastric region
upper middle portion of the abdomen; between the midclavicular line and above the subcostal line
subcostal line
superior horizontal line; below the hypochondriac and epigastric region; above the lumbar and umbilical region
lumbar region
to the right and left of the umbilical region, near the waist; middle region between the midclavicular line and below the subcostal line
umbilical region
centermost region of the trunk
intertubercular line
inferior horizontal line; below the lumbar and umbilical region; above the inguinal and hypogastric region
inguinal region
the right and left regions of the hypogastric region; below the intertubercular line
hypogastric region
lower middle portion of the abdomen; below the intertubercular line
midclavicular line
imaginary vertical line bisecting the middle of the clavicle in each hemithorax
appendicular regions
consists of the upper and lower limbs
arm (brachial); forearm (antebrachial); wrist (carpal); hand (manual); fingers (digits)
parts of the upper limbs
brachial
arm
antebrachial
forearm
carpal
wrist
manual
hand
digits
fingers/toes
thigh (femoral); leg (crural); ankle (tarsal); foot (pedal); toes (digits)
parts of the lower limbs
femoral
thigh
crural
leg
tarsal
ankle
pedal
foot
epithelial; muscle; nervous; connective
four types of animal tissues
loose connective; bone; cartilage; blood
four types of connective tissues
epithelial tissues
a sheet of closely adhering cells; usually exposed to the environment or internal space (coelom)
coelom
body cavity; internal space
protection; absorption; secretion; excretion; filtration; sensation
six functions of epithelial tissues
tight junctions
a specialized connection of two adjacent animal cell membranes such that the space usually lying between them is absent
gap junctions
provide cytoplasmic channels between adjacent cells
adhering/anchoring junctions (desmosomes)
cement cells together
squamous
flat cells
cuboidal
cube-shaped cells
columnar
column-shaped/rectangular cells
pseudostratified
faux-layered
stratified
multiple layers
simple squamous epithelium
single layer of thin cells; shaped like fried eggs; flattened nucleus; allows rapid diffusion/transport of substances through membrane; secretes lubricating serous fluid
representative locations of simple squamous epithelia
alveoli; glomerular capsules; kidney tubules; heart and blood vessel endothelium; stomach serous membrane; intestines; pleura surface mesothelium; pericardium; peritoneum; mesenteries
simple cuboidal epithelium
single layer of cube-shaped cells; spherical, centrally placed nuclei; found in the liver, thyroid, mammary and salivary glands, most kidney tubules, bronchioles; absorption and secretion; production of protective mucous coat; movement of respiratory mucus
simple columnar epithelium
single layer of tall, narrow cells; oval or sausage-shaped nuclei; vertically oriented, usually in basal half of cell; found within the inner lining of stomach, intestines, gallbladder, uterus and uterine tubes, some kidney tubules; absorption; secretion of mucus and other products; movement of egg and embryo in uterine tube
pseudostratified columnar epithelium
some cells do not reach free surface, but all cells reach basement membrane; nuclei at several levels in deeper half of epithelium; often with goblet cells; often ciliated; found in the nasal cavity to bronchi and portions of male urethra; secretes and propels mucus
keratinized stratified squamous epithelium
multiple cell layers with cells becoming increasingly flat and scaly toward surface basal cells may be cuboidal to columnar; found in the epidermis and on palms and soles; resists abrasion and penetration by pathogenic organisms and retards water loss
nonkeratinized stratified squamous epithelium
same as keratinized epithelium but without surface layer of dead cells; found in the tongue, oral mucosa, esophagus, anal canal, and vagina; resists abrasion and penetration by pathogenic organisms
keratinization
accumulation of keratin in a tissue; a sign of vitamin A deficiency
stratified cuboidal epithelium
two or more layers of cells; surface cells are square or round; found within the sweat gland ducts, egg-producing vesicles (follicles) of ovaries, sperm-producing ducts (seminiferous tubules) of testis; contributes to sweat secretion; secretes ovarian hormones; produces sperm
gland cells
epithelial cells that produce secretions
exocrine glands
secrete chemical substances into ducts that lead either to other organs or out of the body
endocrine glands
glands that secrete chemicals called hormones directly into the bloodstream
carcinomas
cancers of the epithelial tissue
connective tissues
most abundant and widely distributed; histologically variable; cells are not in direct contact with each other; binding of organs; support; physical protection; immune protection; movement; storage; heat production; transport
fibroblast
produces fibers and ground substance
macrophages
phagocytic cells that engulf pathogens, foreign particles and dead/dying cells
leukocytes/white blood cells
neutrophils: attack bacteria; lymphocytes: react against pathogens
neutrophils
white blood cells that attack bacteria
lymphocytes
white blood cells that react against pathogens
plasma cells
detect foreign agents; produce antibodies
mast cells
produces heparin: inhibit bloodclots; and histamine: increases blood flow by dilating blood vessels
heparin
an anticoagulant which inhibits blood clots
histamine
a compound which increases blood flow by dilating blood vessels
adipocytes
fat cells for food storage and heat production
collagenous fibers
made of collagen; tough and flexible; resists stretching; synthesis requires vitamin C
reticular fibers
thin collagen fibers coated with glycoprotein; forms a sponge-like network
elastic fibers
thinner than collagenous fibers; branch and region; made of elastin coated with a glycoprotein (fibrillin); a coiled structure allowing it to stretch and recoil
ground substance
gelatinous to rubbery consistency made up of glycosaminoglycans, proteoglycans; and adhesive glycoproteins; absorbs compressive forces and protects cells from mechanical injury
loose connective tissue; dense connective tissue
two kinds of connective tissue proper
loose connective tissue
underlies most epithelia; provides elastic support and serves as a fluid reservoir
areolar tissue
loose arrangement of collagenous and elastic fibers; scattered cells of various types; abundant ground substance; numerous blood vessels
representative locations of areolar tissue
underlying nearly all epithelia; surrounding blood vessels; nerves, esophagus, and trachea; fascia between muscles; mesenteries; visceral layers of pericardium and pleura
functions of areolar tissues
loosely binds epithelia to deeper tissues; allows passage of nerves and blood vessels through other tissues; provides an arena for immune defense; blood vessels provide nutrients and waste removal for overlying epithelia