important lit

Cheung, Lai, Ng 2005

32.5% of abutments need Endo, 15.6% of PFM crowns developed pulpal necrosis

, 14 year followup

Krasner and rankow 2004

Pulp chamber laws

Bystrom 1985

E. Facelis has a proton pump making it resistant to CaOH

Kuttler 1955

Major foramen doesn't coincide with vertical apex

Stein, Corcoran 1990

Major foramen doesn't coincide with vertical apex (only 21%). Separate with time due to age. Minor to major .724mm. CDJ .189mm constant

Sam Kahler 2018

Thin fragile roots not long term CaOh placement responsible for root fracture, "Kahler et al found that the use of long term calcium hydroxide for up to 9 months had no great effect on the fracture susceptibility compared to controls in an in vitro study utlizing lamb teeth"

Ricucci 2018

Extra-radicular infection found in 83% of cases with chronic abscesses

Rosenberg 1998

Occlusal reduction may be effective if reducing post-op pain with vital pulp, percussion positive and pre-op pain

Ricucci 2014

Found histologically speaking diagnosis 97% matched fundings in normal or reversible and 84% matched in SIP

Cameron 1976

CTS additional findings only 25% of cracked teeth needed endo or EXT

Davis 2019

success rates of upwards of 90.6% at 2 to 4 years postreatment were reported by davis and shariff with impromvents in success noted when microscope assisted intraorifice barrier were placed apical to the crakcs, occlusal reduction was performed postoperatively and full ocverage restorationswere placed expeditiously"

Awawdeh 2017

RCT therapy decreases reception to bite force. RCT have higher bite force

Walton 1984

fractures of teeth---> bacteria demostrated in fracture lines of fractured teeth. Fractures often contained debris and inflamatory mediators, Inflamamtion on edge of teeth which accounts for bone loss

branstrom 1986

hydrodynamic theory of pulp sensitivity

Mainkar and Kim 2018

Cold testing: Sensitivity 87% (nonvital) specificty: 84% (vital). overall cold is 84% accurate.

Heat testing Sensitvity .78(necrotic) Specfiicty .67 (vital) Heat .72% accurate

EPT .72 senstivity (necrotic) .93 specficity (vital). EPT 82% accurate

Pusle and LDF 97% accurate

Fayad 2012

Fractures: Midroot loss of bone with intact bone coronal and apical to defect, absence of the entire buccal plate, midroot radiolucency in area of post termination and space between the buccal or lingaul plate and the root srface

lin 2014

tooth extraction hazard ratio for the RCT with rubber dams was significantly lower than that observed for RCT without rubber dams (hazard ratio = 0.81; 95% confidence interval, 0.79-0.84).probability of initial RCT using rubber dams after 3.43 years (the mean observed time) was 90.3%, which was significantly greater than the 88.8% observed without the use of rubber dams (P < .0001).

Krell and Riveria 2007

only 21% of teeth that were cracked with RP ended up needing endo

read 2014

ibuprofen can signifcantly affect the results of cold, percussion and palpation testing, whereas it does not affect bite force.

Nagaoka 1995

odontoblastic processes and dentinal fluid provide barriers to bacterial invasion into pulp in vital teeth. In nonvitial teeth these pathways are open for a bacteria invasion leading to eventually a infected tooth even in initial cases of asepctic necrosis assuming bacteria can find a way through intial enamel layer

(Gorni & Gagliani, 2004)

altered anatomy from intitial RCT treatment leads to successful outcomes in retreatment cases only 47% of the time, overall success was 69% and those with respected anatomy 86.8%

Mattison 1984

No difference in external root resorption in orthodontically treated teeth vs vital teeth in a cat study model at 6 months

Sjogren 1990

8-10yr recall

Vital cases: 96% success rate. Over-extended filling materials here are not problematic

Necrotic cases with lesion: 86% success rate. However this jumps to 90% if canal was instrumented to length and is only 69% in cases where they could not instrument to length

For N/PARL cases:

Obturation 2mm from apex: 94% success

Long: 76%

>2mm short: 68%

Retreatment with lesion: 62% success rate

Flare ups and AAA have no effect on long term success

Langeland 1977

No relation between radiographic lesions and patient symptoms. 14% of lesions contain bacteria

Bergenholtz 1977 and 1982

bacteria in the oral cavity can induce pulpal inflamation, 1982 showed that its leakage around restorations by bacteria that cause inflamation, not the materials themselves

Riccucci 2020

No histological, clinical, bacteriological difference in true vs. bay cysts. No reason bay cysts should heal and true cysts shouldnt. ALL associated with intraradicular infection. True cyst is not a self sustaining entity. CYST THEORIES CITED IN THIS PAPER

merdad 2011

ETT have higher caries risk than non-endodontically treated teeth with restorations

Caviedes-Bucheli 2017

Excessive occlusal forces reduce pulpal blood flow and oxygenation, stimulating angiogenesis through both direct effects of substance P on endothelial cells and fibroblasts and indirect effects mediated by inflammatory cells that release angiogenic growth factors. These newly formed blood vessels support pulp repair by supplying oxygen and nutrients, promoting collagen production, recruiting stem cells and inflammatory cells, and facilitating the formation of tertiary dentin as a defense mechanism against continued mechanical injury. If occlusal trauma persists beyond the pulp's reparative capacity, continued inflammation and vascular compromise may ultimately lead to pulp necrosis

Riccucci 2021

Symptomatic irreversible pulpitis consistently involves bacterial infection, not just inflammation. Every tooth in the study exhibited bacteria within pulp blood vessels. Infection remains concentrated in the coronal pulp, with no intravascular bacteria detected in the middle or apical root thirds. Reversible pulpitis does not have bacterial invasion

Ricucci 2006

Radiographs cannot be used to distingush cysts vs granulomas

Ricucci 2021 perio and pulp

Cementum is essential for protecting the pulps. In teeth with perio pockets and cementum loss pulp inflamation was seen

Sundqvist 1998

Well treated teeth have a high success rate in retreatment (74%). Larger lesions and positive cultures at time of obturation are associated with higher rates of failure. Most persistent infections are due to singular bacterial species, usually E. Facelis

Ricucci 2010

Apical periodontitis is a biofilm induced disease. Larger lesions/cystic lesions tend to have more biofilm representing a time dependent growth

Baumgartner 1991

Endodontic microbial communities progress from more areobic species to fewer anerobic (5 on average) species due to reduced oxidative potential over time as the infection progresses

Debelian 1995

Intrumenting beyond the apex has no effect on levels of transient bactermia which is induced on average about 44% of th time

Du 2014

6% bleach was more effective than 2% chx or bleach at killing E.F biofilms. Peak killing time was at 3 minutes with effects decreasing signficantly after 10 min. More mature biofilm were more resistent to solutions

Fabricius 2006

The key finding was that eliminating bacteria from the root canal system before permanent root filling was the most important factor for successful healing of periapical tissues, whereas the technical quality of the root filling alone had a limited effect if bacteria persisted.

Distel 2002

Enterococcus faecalis can survive intracanal medicaments by forming true biofilms, making it dramatically more resistant to disinfection and a major driver of persistent endodontic infections. This study provides direct SEM and confocal evidence that E. faecalis develops organized, mushroom‑shaped biofilm structures inside medicated root canals, even in the presence of calcium hydroxide—explaining why this organism is so difficult to eliminate in retreatment cases. CAOH paste kept biofilm away for 77 days

Sequira 2004

Candida is present in 21% of samples of teeth with infection

Ricucci and Bergenholtz 2004

bacteria are usually confined to the root canal space, Apical periodontitis is a host inflammatory response to infection originating within the root canal system the inflammatory lesion develops at the microbial–host tissue interface around the apical foramen, where bacterial antigens and virulence factors stimulate the host response rather than requiring extensive bacterial invasion of the periapical tissues. PA lesions not from bacteria themselves

Vital pulp tissue can be found in teeth testing necrotic. Thus clincal testing more closely indicates coronal pulp status rather than apical pulp status in some cases

clinical pulp testing reflects the condition of the coronal pulp rather than every portion of the root canal system.

Ricucci and Langeland 1998

overfilling with GP or SEALER is associated with peristent inflamation beyond apex, best healing occured when filling material is kept within minor constriction. DO NOT OVERFILL

Easlick 1951

Refuted focal theory of infection. Extractions of ETT do not routinely improve pt overall health

Sundqvist 1976

Refuted the theory of anchorsis. findings strongly supported that bacteria enter through: caries, coronal leakage, cracks, trauma with exposure, rather than via the bloodstream.

sterile necrotic pulps lack PA lesions

Krell 2018

Cracked teeth have a fairly high success rate (82%), which decreases signficantly when probing depths extend 5mm or more (35ish) or there is dual MMR and DMR cracks (62%). Pulpal and apical diagnosis also play a role in success rate but to a lesser degree, with necrotic cases and cases with lesions/sinus tracts having lower success rates

Peters 1994

EPT is more prone to false positives, cold more prone to false negatives (14% of pt over 50). Cold test in cervical buccal region for best results.

Chogle 2020

CT scans have a signficant effect on providers decison making regarding treatment (49% change in treatment decisions with CT) and etiological agents responsible for endodontic pathosis (54% change in ascribed etiological agent of pathosis)

Ee 2014

reoperative CBVT imaging provides additional information when compared with preoperative periapical radiographs, which may lead to treatment plan modifications in approximately 62% of the cases

Sjogren 1991

7 days of calcium hydroxide was sufficient to eliminate cultivable bacteria in the vast majority of infected canals. Must dress for at least 7 days

Siqueria and Lopez 1999

Review demonstrating that hydroxyl ion diffusion peaks over the first 2–3 weeks, while dentin and tissue fluids progressively buffer the alkaline environment, resulting in a gradual decline in antimicrobial effectiveness rather than an abrupt loss of activity."