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Scientific method
Observation → Question → Hypothesis → Prediction → Experiment → Analyze results → Report results or revise hypothesis
Observation
The process of noticing or identifying something that leads to a scientific question.
Hypothesis
A suggested explanation for an event that is testable and falsifiable.
Prediction
A specific expected result based on a hypothesis.
Experiment
A test that manipulates a factor to see how it affects an outcome.
Variable
Any part of an experiment that can vary or change.
Control group
The group that has every feature of the experimental group except the experimental manipulation.
Independent variable
The variable the experimenter manipulates or changes.
Dependent variable
The variable being tested and measured; it depends on the independent variable.
Falsifiable
A hypothesis is falsifiable if experimental results can disprove it.
Scientific inquiry
An ongoing cycle involving exploration, testing ideas, community analysis and feedback, and benefits/outcomes.
Peer review
The process where scientists receive feedback from other scientists on their work.
Replication
Repeating scientific research to see whether similar results can be obtained.
Basic science
Science that seeks to expand knowledge regardless of short-term application.
Applied science
Science that uses knowledge to solve real-world problems.
Order
A property of life in which living things are highly organized, structured, and made of cells.
Response to environment
The ability of living organisms to sense and respond to their surroundings.
Reproduction
The ability of living organisms to produce offspring.
Adaptation
A heritable trait that increases survival and reproduction through natural selection.
Growth and development
The increase in size and/or changes that occur as an organism develops.
Homeostasis
The maintenance of a relatively stable internal environment.
Energy processing
The ability of living organisms to obtain and use energy.
Evolution
Change in allele frequencies in a population over time.
Phylogenetic tree
A diagram that illustrates evolutionary relationships between organisms.
Three domains of life
Bacteria, Archaea, and Eukarya.
Prokaryotes
Organisms such as Bacteria and Archaea that lack intracellular organelles.
Levels of organization
Organelles → cells → tissues → organs/organ systems → organisms → populations/communities → ecosystems → biosphere.
Species
An evolutionarily independent population or group of populations.
Biological species concept
Defines species based on reproductive isolation; members do not interbreed or fail to produce viable, fertile offspring.
Morphospecies concept
Defines species based on differences in size, shape, or other morphological features.
Phylogenetic species concept
Defines species based on evolutionary history.
Speciation
A splitting event that creates two or more distinct species from an ancestral species.
Natural selection
The process in which heritable variation leads to differences in reproductive success.
Darwin and Wallace
Scientists who independently proposed natural selection as a mechanism of evolution.
Darwin's first postulate
Individuals in a population vary in their traits.
Darwin's second postulate
Some differences between individuals are heritable and passed to offspring.
Darwin's third postulate
More offspring are produced than can survive.
Darwin's fourth postulate
Individuals with certain heritable traits are more likely to survive and reproduce.
Evolution
A change in the allele frequencies of a population over time.
Biological fitness
The ability of an individual to produce surviving, fertile offspring relative to other individuals in the population.
Adaptation
A heritable trait that increases an individual's fitness in a particular environment.
Selection
Differential reproduction resulting from heritable variation.
Galápagos finches
Finches with different beak forms associated with different types of food use.
Fossil
A trace of an organism that lived in the past.
Fossil record
The many fossils found and described in scientific literature.
Radiometric dating
A method that uses radioactive decay to assign absolute ages to materials.
Earth's age
About 4.6 billion years old according to the study guide.
Extinct species
Species that no longer exist.
Transitional feature
A fossil trait that is intermediate between ancestral and derived species.
Vestigial trait
A reduced or incompletely developed structure with no or reduced function that resembles a functioning structure in a related species.
Natural selection requirements
Heritable variation and differential reproductive success.
Population-level evolution
Evolution occurs when allele frequencies change in a population across generations, not because an individual needs or chooses a trait.
DNA
Deoxyribonucleic acid; stores genetic information in its base sequence.
DNA bases
Adenine (A), guanine (G), cytosine (C), and thymine (T).
DNA nucleotide
A phosphate group + 5-carbon sugar + nitrogenous base.
Purines
Adenine and guanine.
Pyrimidines
Cytosine and thymine.
DNA base pairing
Guanine pairs with cytosine; adenine pairs with thymine.
Antiparallel
DNA's two strands run in opposite directions.
Gene
A stretch of DNA that codes for something.
Allele
A sequence variant of a gene.
Genotype
The allele combination or genetic makeup of an organism.
Phenotype
The characteristics or observable traits of an organism.
Gene-to-protein sequence
DNA → transcription → mRNA → translation → protein → phenotype.
Transcription
The process that produces mRNA from DNA.
Translation
The process in which a ribosome uses mRNA to build a polypeptide/protein.
mRNA
Messenger RNA that carries information from DNA to the ribosome.
tRNA
RNA that brings amino acids to the ribosome during translation.
Codon
A sequence on mRNA that pairs with an anticodon during translation.
Anticodon
A sequence on tRNA that pairs with a codon.
Environmental effect
A change caused by environmental conditions that does not necessarily involve a change in allele frequencies.
Evolution vs environmental change
Evolution involves a change in allele frequencies across generations; environmental effects can change traits without changing allele frequencies.
Chromosome
A strand of DNA packaged with proteins called histones.
Sister chromatids
Two identical copies of one replicated chromosome held together at the centromere.
Centromere
The region where sister chromatids are held together.
Cell cycle
Interphase (G1 + S + G2) followed by M phase.
G1 phase
The first gap phase; chromosomes are unreplicated.
S phase
The DNA synthesis phase; DNA replicates.
G2 phase
The second gap phase; the cell prepares for division.
M phase
The phase containing mitosis and cytokinesis.
Mitosis
Cell division that produces two genetically identical daughter cells in the study guide's model.
Prophase
Chromosomes condense and the spindle apparatus begins to form.
Prometaphase
The nuclear envelope breaks down and microtubules contact chromosomes at kinetochores.
Metaphase
Chromosomes line up at the middle/equator of the cell.
Anaphase
Sister chromatids separate and move to opposite poles.
Telophase
The nuclear envelope reforms and chromosomes de-condense.
Cytokinesis
The division of the cytoplasm that produces separate daughter cells.
Mitosis outcome
Two genetically identical daughter cells.
Mitosis chromosome number
Mitosis does not reduce chromosome number in the study guide's model.
Ploidy
The number of complete sets of chromosomes in a cell.
Diploid (2N)
A cell with two chromosome sets, one from each parent.
Haploid (N)
A cell with one chromosome set.
Homologous chromosomes
The two copies of a chromosome inherited from the two parents.
Sister chromatids
Two identical copies made when one chromosome replicates.
Meiosis I
The reductional division in which homologous chromosomes separate and chromosome number is reduced.
Meiosis II
The division in which sister chromatids separate.
Prophase I
Chromosomes condense, homologous chromosomes pair, and crossing-over occurs.
Crossing-over
The exchange of genetic material between homologous chromosomes during Prophase I.
Metaphase I
Homologous chromosome pairs line up at the equator.
Anaphase I
Homologous chromosomes separate and move to opposite poles while sister chromatids remain together.