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genetics and a little bit of inheritance
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trait
version of an inherited characteristic
true-breeding
produces offspring that are genetically identical for one or more traits when self-pollinated or crossed with another true breed
hybrid
offspring of 2 different true breeds
cross
breeding of 2 diff organisms
p generation
parent generation
F1 generation
filial generation
monohybrid cross
used to study inheritance of 1 trait
complete dominance
1 allele expressed despite presence of another
incomplete dominance
partial expression, neither allele dominates and both have an influence on the individual. Eg snapdragons CR CW CRCW pink
codominance
both alleles expressed fully at the same time. Eg shorthorn cattle, HR HW HRHW roan
Pedigree
tracks propagation of a trait through generations
autosomal inheritance
inheritance of alleles on autosomes, all genders affected equally
sex-linked
found on x or y chromosome
x linked
phenotypic expression of an allele that is found on the X chromosome. Can't be a father to son
y linked
phenotypic expression of an allele that is found on the Y chromosome. Only father to son
cystic fibrosis
body produced thick mucus that clogs the lungs and pancreatic duct, autosomal recessive allele
hemophilia
body can't form blood clots. Causes jaundice, vomiting, diarrhea; may lead to death. X Recessive allele
Phenylketonuria (PKU)
phenylalanine accumulation in blood. Causes poor mental development and growth, weak enamel. Autosomal recessive
Huntington's disease
progressive degenation of nervous system. Causes loss of muscl control and cognitive ability. Shows late, autosomal dominant
sickle cell anemia
red blood cells shaped like C. causes blocked blood flow. autosomal recessive
red-green color blindness
genetic mutation, x linked recessive
mutation
change in genetic code
dihybrid cross
cross involving two traits
hemizygous
only one allele present (eg. xy, hemizygous)
mendel's method
remove male reproductive organs from pea plants, cross-pollinated plants, allowed offspring to self pollinate
why was mendel's method good
large sample size, fast breeding, repeated, and he looked for patterns, chose characteristics with 2 alleles for easy distiction
ABO Blood types
complete and codominance, IA and IB codominate and completely dominate i.
A can:
receive A and O
B can:
receive B and O
AB can
receive AB A B and O
O can
Receive O
RH factor
protein antigen on surface of red blood cells. Rh+ and Rh-
If blood cell is Rh+:
Has D antigen, Can receive both pos and neg
If blood cell is Rh-:
Has D antibody, can only receive neg or will agglutinate
recessive autosomal on pedigree
affected offspring from unaffected parents
dominant autosomal on pedigree
affected parents but unaffected child