Electron Transport Chain

FADH and NADH converted into ATP

Electron transport chain

Electron carriers of ETC

NAD, FAD, Coenzyme Q

The ETC is made up of four complexes known as ...

respiratory complexes

Where are the respiratory complexes located?

inner mitochondrial membrane

Complex I

NADH-CoQ Oxidoreductase

Where does complex I transfer electrons?

NADH to FMN to Fe-S cluster to CoQ

What does complex I contain?

flavoprotein (FMN) and iron-sulfur cluster

What does Fe-S cluster do with the protons?

pump them into intermembrane space

Where do the protons CoQ received come from?

mitochondrial matrix

CoQ can move across the membrane via

lateral diffusion

Complex II

Succinate CoQ Oxidoreductase; aka succinate dehydrogenase

Where does complex II transfer electrons?

electrons (used to convert succinate to fumerate) to FADH2 to Fe-S cluster to CoQ

Are protons pumped in complex II?

no

redox-active proteins containing a heme, but don't carry oxygen

cytochrome

Complex III

CoQ-Cytochrome c Oxioreductase

Where does complex III transfer electrons?

CoQH2 to Fe-S to cytochrome C; CoQH to CoQH -> CoQH2 and CoQ

How many electrons can cytochrome C carry?

1 electron

What does cytochrome C do with protons?

pumped out of the complex

Complex IV

Cytochrome C Oxidase

Where does complex IV transfer electrons?

Cytochrome C to Complex IV/ Cu to Fe to Oxygen

What does complex IV need to function?

Copper

What does complex IV do with protons?

pumps protons out of the matrix

What happens to Oxygen?

reduced to water

Why are CO and CN- poisonous?

block flow of electrons from cytochrome C to oxygen

Electrons from complex I can bypass ...

complex II