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Hormones
Chemical messengers that are synthesized, stored, and released into the blood by endocrine glands
Endocrine glands
Body structures specialized for releasing hormones into the blood
List some endocrine glands
Pituitary gland, adrenal gland, thyroid, parathyroid
Hormones are intimately involved with____and____
MPS, degradation mechanisms
Anabolic horomones
Tissue building
Catabolic horomones
Degrade tissues
Permissive hormones
Allow
Examples of anabolic horomones
Testosterone, growth hormone, IGF-1
Permissive hormone examples
Thyroid
Catabolic hormones
Cortisol, progesterone
Lock-and-key theory
Key=hormone, lock=receptor
Downregulation
The inability of a hormone to interact with a receptor
Hormonal adaptations can involve:
More/less hormone synthesis, faster/slower hormone clearance, more/fewer receptors
3 Types of hormones
Steroid
Polypeptide
Amine
Steroid hormones
Derived from adrenal cortex, at soluble, can pass through cell membrane (testosterone)
Polypetide
Made of AA, Bind to receptors on the cell membrane and use signaling pathways/secondary messengers, (growth hormones/insulin),
Amine
Made from tyrosine and tryptophan, secondary messanagers, not regulated by negative feedback
Resistance exercise causes ____
hormones to be released befpre during and after
Hormonal responses demand on…
Exercise intensity
Volume
Muscle mass
Rest periods
Training experience
What is a primary anabolic hormone
Testosterone
Testosterone is increased by
Large muscle group exercises, 85-95% 1RM, mod-high volume, 30secs-1min rests, 2+yrs of training
Free vs. total testosterone percentage
.5-2% of TT is FT
Heavy resistance exercise can acutely increase free testosterone in both men and women, but the increase is much smaller in women.
True
Women have approximately
15–20× lower circulating testosterone than men
How to increase cortisol
High volume + large muscle groups + short rest periods
Acute cortisol___
increases can contribute to muscle remodeling and maintenance of blood glucose`
EIMD
Exercise induced muscle damage
Process of EIMD
Lift weights-EIMD-DOMS-endocrine system turns on-signals mTor