Skeletal_System

Chemisorption

The accumulation of labeled phosphate compounds on the hydroxyapatite crystal surface of the bone.

Blood Pool Image

Image obtained immediately after radiopharmaceutical administration when increased blood supply indicates higher activity.

Paget Disease

A condition where bone formed is abnormal, enlarged, brittle, and prone to fractures.

Radiopharmaceutical for Bone Imaging

[Tc-99m]hydroxymethylene diphosphonate (HDP) and [Tc-99m]methylene diphosphonate (MDP).

Normal Bone Imaging Results

Symmetric, uniform uptake with increased activity in joints and scapulae.

Abnormal Results - Super Scan

Bright bone uptake with diminished activity in kidneys, bladder, and extremities.

Osteomyelitis Uptake

Increased uptake in flow, blood pool, and delay images indicates osteomyelitis.

Patient Preparations

Administration of 4-6 glasses of liquid to reduce radiation to bladder and aid in clearance of RP.

Contradictions for Bone Imaging

Pregnancy/breast-feeding, recent nuclear medicine study, and no oral contrast within 24-48 hours.

Bone Scanning Phase 1

Flow imaging with 1 second/frame for 60 frames, capturing blood flow immediately after injection.

Bone Scanning Phase 4

24-hour delay imaging for better uptake of the radiopharmaceutical.

Tc-99m Dose

20-30 mCi administered intravenously.

Epiphyseal Plates

Show increased uptake in growing children.

Intervention for Infiltrated Dose

Hydrate the patient and image approximately 6 hours later.

Bone Remodeling

The process by which bone tissue is continuously renewed through the coordinated actions of osteoclasts and osteoblasts.

Bone Scanning Phase 2

Blood pool imaging to assess vascularity in the bone; typically performed 5-10 minutes post-injection.

Bone Scanning Phase 3

Static imaging, capturing images of bone activity typically 2-4 hours after radiopharmaceutical administration.

Indications for Cellulitis Detection

Higher radiotracer absorption may suggest the presence of cellulitis linked to inflammatory conditions in the bone.

Gastric Artifact in Imaging

Artifacts that appear due to the presence of gastric contents, potentially obscuring underlying structures in bone imaging.

Glove Artifact

An imaging distortion caused by external materials, such as gloves, that can create unwanted shadows or patterns on radiographs.

Bladder Artifact in Imaging

Unwanted effects on images related to the bladder's filled state or lesions, which can confuse the interpretation of radiologic findings.