Sympathetic nervous system adrenergic receptors

B1 location (1)

Heart

B2 location (6)

lungs, GI, liver, uterus, smooth muscle, blood vessels

B3 location (2)

fat cells and brown fat

a1 location (3)

mooth muscle, heart and liver

a2 location (4)

thrombocytes, vessels, nerve terminals, pancreatic islands

activation of B1

increase HR and strength, stimulates renin release by kidneys

activation of B2

increases respiration, inhibits GI tract and relaxes uterus

B3 activation

sitmulates lipolysis

a1 activation

dilates pupils and and constricts bloodvessels and sphincters

a2 activation

inhibits NE release, insulin secretion and promots blooth clotting