Chapter 20- The Molecular Revolution: Biotechnology, Genomics, and New Frontiers

CRISPR locus

CRISPR locus

The ________ is transcribed into a long pre- crRNA.

Cas proteins

________ are enzymes (more precisely, endonucleases) that serve to cut DNA that is complementary to a crRNA.

Metagenomics

________ is the only way to get a good handle on types of microbes present in an environment.

Synthetic biology pursues

________ knowledge by building biological systems and discovering what properties they demonstrate.

Polymerase chain reaction

________ (PCR) provided a quicker way to clone DNAs.

Transposable elements

________ are DNA segments that can move from one place to another within the genome.

Biologists

________ use the term transcriptome in referring to the complete set of RNA molecules that have been transcribed in a particular cell, and proteome in referring to the complete set of proteins that are produced.

Gene therapy

________ is any approach to treating or curing disease that involves modifications of the genome.

Biotechnology

________ is the engineering of genes, cells, and organisms for basic research as well as practical purposes.

Bioinformatics

________ is a field that fuses mathematics, computer science, and biology to manage and analyze sequence data.

Cells

________ that take up DNA from the environment and incorporate it into their genomes are said to undergo transformation.

method

The first ________ for sequencing DNA that came into widespread use is called dideoxy sequencing.

Single nucleotide polymorphism

________ (SNP) is a site in DNA that varies at a single base pair.

Systems biology

________ seeks knowledge of how the network of interactions between the individual parts of a biological system lead to properties of life.

animal model

A(n) ________ is a laboratory animal with disease symptoms that parallel those of a human disease.

shotgun sequencing

In ________, many copies of a genome are broken up randomly into a set of fragments of various sizes.

complementary DNA

A crRNA binds to the ________ sequence of an invading virus, but it doesn't act alone.

DNA cloning

One of the most basic requirements of recombinant DNA technology is the ability to produce many copies of a gene or other DNA sequence of interest, a process referred to as