(GORD)

Flashcards covering the anatomy of the stomach, effects of ageing on digestion, diagnostic tests, and pharmacological treatments for Gastro-oesophageal Reflux Disease (GORD).

Gastric Juices

The stomach secretes large volumes of these, which include mucus, acid, and enzymes.

Pylorus

The specific part of the stomach that connects to the small intestine.

Parietal cells

Specific cells in the stomach responsible for secreting Hydrochloric acid ($HCl$) and intrinsic factor.

Ageing impacts on digestive function

Changes include decline in taste buds, diminished sense of smell, decreased salivary secretion, and decreased oesophageal and gastric motility.

Borborygmus

A rumbling or gurgling sound produced by the movement of fluids and gases in the intestines.

Bernstein test

A medical test designed to measure oesophageal acidity.

Typical clinical features of GORD

Includes burning retrosternal pain, irritation of the airways (chronic cough), and dysphagia.

Proton Pump Inhibitors (PPIs)

A class of medications used to treat GORD; examples include Omeprazole, Esomeprazole, and Pantoprazole.

H2-receptor antagonists

A class of medications used to treat GORD; examples include Ranitidine and Cimetidine.

Gastro-oesophageal Reflux Disease (GORD)

An alteration to the gastrointestinal system involving reflux, potentially leading to complications such as asthma and other respiratory issues.