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anterograde amnesia
inability to form & retain new memories after it just happened [ due to a specific injury ]
retrograde amnesia
unable to recall memories of their experiences / events / information that has already happened before. [can’t remember something from their past due to an injury which caused this problem.]
declarative memory
facts & events that you can state/declare to recall.
remembering and stating your personal narrative of life.
implicit memories [non-declarative]
things like skills, habits, conditioned responses such as riding a bike or texting.
Korsakoff’s syndrome
A neurological disorder of the central nervous system which leads to amnesia, specifically impairing the declarative memories; caused by nutritional deficiency of Vitamin B.
declarative memories are
stored & widely distributed across cortical regions of the brain {the neocortex} not just in the medial temporal lobe.
declarative memory
the form and organization depends on medial temporal lobe structures [hippocampus etc]. MTL only acts as a hub to connect information from different parts of the brain [for encoding & consolidation].
medial temporal lobe [MTL]
important for forming and combining declarative memories.
works as a hub to bring together information from different brain areas. damage can cause anterograde amnesia.
includes hippocampus, entorhinal corte, perirhinal cortex, and parahippocampal cortex.
frontal lobe
controls planning, decision making, problem solving, & impulse control.
involved in movement (motor cortex) & speech production (brocas area)
plays a big role in personality, emotions, & social behavior
mammillary bodies
small round structures on the underside of the brain [part of the hypothalamus]
important for memory processing & recall, works with the hippocampus & thalamus in the limbic system.
damage linked to memory disorders [korsakoff syndrome]
episodic memory
memory of personal experiences - events tied to a specific time and place like remembering your 10th bday. “Episodes of your life”
procedural [motor] memory
a type of non-declarative long term memory; capable of remembering how to perform a task without conscious thought. [typing / riding a bike]
electrodes
tools that record brain activity (like EEG) or stimulate neurons with small electrical signals. (helping neurons fire)
white matter
made of myelinated axons. Speeds up communication between brain regions.
brains “highways”
Gray matter
made of cell bodies, dendrites, synapses. Handles thinking, memory, decisions.
Brains “processing centers”
Gliosis
Brains healing responses to injury. Glial cells activate, clean up, and may form a glial scar.
multiple traced theory (MTT)
every time we recall a memory, the brain creates a new trace (a new version of that memory) in the hippocampus & cortex. [old memory stored in the hippocampus & cortex).
recalling strengthens memory but can also change it slightly.
remembering = re-storing, not just replaying.
Semantic memory
memory of facts and knowledge. Not tied to a specific time. [ex.knowing 2 + 2 = 4 or knowing Paris is the capital of France]. “General Knowledge”
The structures of the medial temporal lobe [MTL]
important for declarative memory [episodic + semantic]
Hippocampus [MTL]
forms new long-term declarative memories [episodic + semantic]. Critical for linking experiences into memory!
main site of neuroplasticity.
functions : learning new information, encoding & consolidating memories, spatial memory place cells - ‘GPS’ of the brain.
Entorhinal Cortex [MTL]
movies information in and out, acting as the gateway between the hippocampus and cortex
like a train station hub connection memory routes.
Perirhinal Cortex
handles object recognition & familiarity. [“Have I seen this before?”].
like your brains object ID scanner.
Parahippocampal Cortex
supports place, context, and scene memory.
like your GPS for memory, remembering where things happened.
Amygdala
is part of the limbic system [emotion & motivation network, helps us feel emotions & drives us to act on them]
detects threats & triggers the fear response
helps attach emotional meaning to memories
hippocampus is part of larger set of structures to the…
limbic system
limbic system is responsible for
emotion, memory , drive / motivation
dentate gyrus [subregion of the hippocampus]
can generate new neurons [neurogenesis] helping pattern, separate between 2 similar experiences
the “entry” [takes in new information]
CA Regions [subregion to the hippocampus]
different roles in memory encoding & retrieval
the “processors” [work with memory signals]
subiculum [part of the hippocampus]
main output, sends information out of the hippocampus
the “exit”, sending info to other brain areas
encoding
process of taking in new information & turning it onto a memory trace [‘saving’ the experience in your brain]
consolidation
process of stabilizing & strengthening that memory, becoming long-term / harder to forget
spatial navigation
brains GPS, helps you know where your are & how to get places
place cells
neurons that fire when you are in a specific location.
discovered by John O’keefe in 1971
grid cells
neurons in the entorhinal cortex that fire in a hexagonal grid pattern as you move through space.
create an internal coordinate system, helping measure distance, track position, & support spatial memory [work with hippocampal place cells]
neuroplasticity
brains ability to change & adapt
hippocampus changes with…
new experiences, neurogenesis, size differences
the cerebral cortex
the outermost layer of the brain [ the wrinkled, folded “gray matter” usually seen in pictures]
responsible for higher brain functions: perception, thought, memory, language, decision making, voluntary movement etc
contains billions of neurons
somatosensory cortex
processes touch, pressure, pain, temperature, and body position
auditory cortex
found in the temporal lobe; processes sound
prefrontal cortex : big 3
planning, decision making, personality
preliminary study
a small practice study done before the main research. it checks if methods, tools, or ideas will work, unlike the main study which collects full results.
research report (study)
a formal written study that presents the full results of research. it explains the question, methods, findings, and conclusions - unlike a preliminary study, which is just a small test run
PNAS
proceedings of the National Academy of Sciences
a leading U.S. scientific journal that publishes important, peer-reviewed research in many fields
parietal lobe helps to
organize spatial information [brains GPS signal] : spatial awareness, navigation, and body position
on top of the brain.
processes sensory information (touch, temperature, pain, pressure)
integrates sensory sensory input to guide movement & perception
occipital lobe
main function;vision processing. located at the back of the brain
interests visual input (color, shape, movement)
works with other lobes to recognize & make sense of what we see
hyposmia
lessen scent of smell.
a medical condition by a partial loss of the sense of smell .
hypo
less of, doesn’t mean NONE
prosopagnosia
visual agnosia.
a neurological condition by the inability to recognize faces.
negative affect
bad mood
agnosia
lacking knowledge due to the loss of the ability to identify objects or people ; inability to interpret sensations & recognize things
gnosis
to know / knowing
exteroception
ability to sense our external world. encompasses 5 senses: touch, sound , smell, sight , taste.
brains processing of sensory input from the external world.
why is exteroception [our senses] important for humans
survival & safety : detects threats , food, and environment
movement & navigation: guides coordination & balance
social & cognition : shapes communication, emotions, memory, and decision-making
exteroception vs interoception - why are they important
they let the brain integrate outer + inner signals to guide behavior, decisions, and well-being.
interoception
senses internal body states (heartbeat , hunger, temperature, pain )
supports homeostasis, emotions, and self-awareness
perceptual memory
allows recognition of sensory patterns (faces, voices, sounds) without relearning.
relies on stored representations of stimuli. Example: knowing your friend’s voice immediately
perceptual learning
long term improvement in detecting or discriminating sensory info through practice/experience.
Example: musicians distinguishing pitches; radiologist spotting tumors more accurately.
priming
implicit memory effect where prior exposure to a stimulus helps makes later recognition / responses faster n more accurate.
example : “yellow” - quicker recognition of “banana”
basal ganglia
subcortical structures involved in movement control, habit/procedural learning, and reward processing.
dysfunctions linked to - Parkinson's , Huntingtons, & OCD
orbitofrontal cortex (OFC)
prefrontal area above the eyes; regulates reward/punishment evaluation, decision-making, and emotion.
damage - impulsivity, poor social judgment.
neocortex
outer layer of the cerebral cortex
supports higher cognition [perception, reasoning, planning, language, memory integration]
specialized regions process different sensory & motor functions.
olfactory cortex
in the temporal lobe, mainly in the piriform cortex, near the amygdala & hippocampus.
functions: identifies / processes odors , links smells with memory & emotion [strong connections to limbic system - explains why smells trigger emotions & emotions] .
involved in reward & aversion learning [smells can drive behavior]
proprioception
sense and awareness of the position & movement of ur body
[ touching ur nose with ur eyes closed - you know where ur arm is in space]
‘where is my body’
somatosensation
bodys sense of touch , pressure , pain , temperature, and vibration - information from the skin, muscles, and joints [feeling the heat of a stove]
‘what am I feeling on/in my body’
afferent
incoming signals - information coming into the brain
in = sensory
efferent
outgoing signals out to body, muscles, organs [ex. dancing]
out = motor
peripheral organs
anything located outside the central nervous system [ brain and spinal cord]
including sensory organs - eyes, ears, nose, skin, taste buds
motor - bones, muscles
heart, lungs, stomach, intestines, liver , kidneys , pancreas, spleen
somatic nervous system (SNS) a part of the peripheral nervous system
voluntary control of the body & relays sensory information - allowing conscious control over actions & reflexes. includes both sensory (afferent) and motor (efferent neurons)
automatic nerves system
involuntary control of body:independent of ur conscious control [beating heart adjusts on its own when walking or running]
parasympathetic afferents can do what
carry signals from organs [heart, hut] mainly through the vagus nerve to the brain stem (NTS)
linked to rest & maintenance
sympathetic afferents can do what
carry sensory signals like pain, temp. , ( internal organs) and intense stress sent through the spinal pathway (CNS)
linked to alert & stress responses
methods
who the subjects are, n (sample size), and what tests/statistics were used
discussion
connects results to past research, gives interpretation, & suggests future studies
what is the basal ganglia and what does it do
a group of deep brain structures involved in movement control, habit learning, and motivation. helps start & regulate voluntary movements, & filters out unwanted or extra movements
damage to the basal ganglia
can lead to movement disorders like Parkinson’s disease (too little movement) or Huntington’s disease (too much movement
passive avoidance involves
withholding a response to avoid punishment