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What is a stem cell
A stem cell can differentiate into different kinds of cells and tissues. Can also make copies of itself creating more stem cells
What are the 4 types of stem cells
totipotent, pluripotent, multipotent, unipotent
What does the totipotent stem cell do
Can form any kind of cell in the body and only found in cygote
What does a pluripotent stem cell do
Can form any kind of body cell and found in blastocysts
What does a multipotent stem cell do
Can only divide into certain types of tissue
What does a unipotent stem cell do
Unspecilalised cells that can only become one type of cell
What is the first step for induced pluripotency
Somatic cell isolation and culture
What is the second step in induced pluripotency
Introduction of reprogramming
What is the third step for induced pluripotency
Reporgramming
What is the fourth step for induced pluripotency
Culture and selection
What is the fifth step for induced pluripotency
Identification and characterisation
What is the cell cycle
The events that take place from one cell division to the next are called the cell cycle
Describe the Gi phase of the cell cycle
The cell producers new proteins, grows and carries out it's normal tasks for the body
Describe the S phase of the cell cycle
The DNA molecules in the cell nucleous from exact copies of themselves
Describe the G2 phase of the cell cycle
This relatively short phase involves preparation for cell division
Describe the M phase of the cell cycle
The cell division divides into two daughter cells, after division the cells may continue the cycle and re enter the Gi phase
mitosis
A type of cell division where 1 parent cell divides once to produce 2 identical daughter cells
What is chromatin
A complex of DNA and proteins found inside the nucleous of eukaryotic cells
What is the primary function of chromatin
Primary function to package very long DNA molecules into more compact denses structures that can fit within the tiny cell nucleus
Why is mitosis important
Creates new body cells that are needed for growth, repair and maintinence
Meiosis
A type of cell division where 1 parent cell divides twice to produce 4 non identical daughter cells
Why is meiosis important
Meiosis allows for the continuity of a species because it means that organism can produce offspring with new gene combinations
What are gametes
Sperm and ova that are produced in the ovaries and testes, are the result of a special type of cell division and meiosis
What is haploid number
Daughter cell with half the number of chromosomes that were present in the original cell
What is the diploid
The number of chromosomes in body cells
What are homologous chromosomes
The chromosomes in diploid cells actually exist in pairs that are identical in shape and carry genetic information that influence the same characteristics
What is genetic variation
A term used to describe the differences between the gametes of individuals of the same species
What is independent assortment
What the genes for different traits sperate into gametes independently of each other, meaning the inheritance of one trait doesn't affect the inheritance of another
What is crossing over
When two paired chromosomes exchange segments of their DNA during the formation of sperm and egg cells, creating new combinations of genetic material
What is fertilization
The joining of a male reproductive cell and a female reproductive cell to form a new single cell, which then develops into a new organism
What is non disjunction
Sometimes one or more of the chromosome pairs may fail to separate when the cell divides in the second meritoic divisions one or more of the chromatids may fail to separate
What is trisomy
A condition in which an individual inherits an extra copy of a chromosome
What is monosomy
Where individuals are missing a chromosome
what is cancer
It is the uncontrolled division of cells that causes the growth of a mass known as a tumor
How are tumors classified
maligant - can spread to other parts of the body
Berign - do not spread to other parts of the body
What are some causes of cancer
Carcinogens are environmental factors known to cause cancer, uv radiation, x-rays, runising radiation, viruses
How can cancer be prevented
Education, legislation, avoid smoking, using sunscreen, personal protective equipment
What is a gene
The fundamental unit of heredity in living organisms
How many genes are in each cell
between 19,000 and 20,000
What 3 things make up a nucleotide
A nitrogen base, a pentose sugar, a phosphate group
What does a triplet contain the information for
A specific amino acid or a stop signal
What are coding and non coding genes
Coding genes are the segments of DNA that contain the instructions for building proteins and non coding genes are regions of DNA that do not directly code for proteins
Describe the process of DNA replication
If order for a cell to divide it must duplicate it's DNA
What is the function of the penis
The penis is the organ that transfers sperm from the male to the female
What is the function of the erectile tissue
Made of spongy tissue and fills with blood during an erection
What is the function of the urethra
Carries sperm outside of the body
What is the function of the foreskin
A sheath of skin that covers the head of the penis
What is the function of testes
The key role of the testes is to produce sperm and hormones
What is the function of the scrotum
The scrotum is a shin covered pouch that hold the testes
What is the function of semin ferrous tubules
Lined with cells which produce sperm
What is the function of the empidymis
Store sperm while they mature
What is the function of interstital cells
Secrete testosterone
What is the function of vas deferens
Carries the sperm away from the testes towards the urethra
What is semen
Sperm transported in liquid called semen
What are seminal vesicles
Secrete thick sugary fluid which provides nutrient for sperm
What is the function of the prostate gland
Secretes thin milky alkaline fluid which neutralises the acidic pH of the vagina
What is the function of the bulbo urethral gland
Secretes a clear mucus that acts as lubricant
What is the function of the ovaries
Contain undeveloped eggs present from birth, make hormones which regulate the mesntural cycle, one of the ovaries release a mature ovum as part of the ovarian cycle
What are the fallopian tubes
Two tubes that connect the ovaries to the uterus
What is the function of the fallopian tubes
Lined with hair like cells called cilia to help move the ovum from the ovary to the uterus
What is the fimbriae
Finger liked projections at the beginning of the fallopian tubes that guide the egg from the ovary into the tube
What is the uterus
A muscular with a soft mucous lining called the endometrium
What is the function of the uterus
The uterus has a role in protecting and nourishing the developing foetus
What is the endometrium
A soft mucus lining
What is the function of the endometrium
The endometrium is shed if an ovum is not fertilised by a sperm
What is the cervix
A ring muscle which dictates to open during labour
What is the vagina
A muscular tube which corrects the cervix to outside the body
What is the hymen
A fold of tissue which covers the opening to the vagina
What is the vulva
Made up of external genital organs of the female
What is the labia major
Two fleshy folds that contain oil secreting glands
What is the labia minora
Beneath the labia major and surround the space to which the urethra and vagina open
What is the clitoris
At the upper end of the labia minora is the elators which contains erectile tissue which fills with blood when stimulated
Where does spermatogenesis occur
Occurs inside the seminferous tubules inside the testes
What is the onset of spermatogenesis
During puberty, the cells lining the seminiferous tubules divide by mitosis
Number of gametes produced by spermatogenesis
four
Where does oogenesis occur
Inside the ovaries
Number of gametes produced by oogenesis
one
What is an oogonium
A diploid germ cell found in the ovaries of female animals and in certain algae and fungi
Define the term primary sex characteristics
Characteristics of sex organs
Define the term secondary sex characteristics
Any physical characteristic that are different between the sexes but are not directly included in reproduction
Define the term hormone
A hormone is a chemical substances, produced by a gland, and carried by the blood, which alters the activity of one or more specific target organs
What do sex hormones do
Sex hormones play a role in the development of primary and secondary sex characteristics
What do FSH and LH do in males
promote the production of testosterone in the testes
What is testosterone
Main male reproductive hormone
What does testosterone do
Stimulates the production of sperm in the testes and helps in development of secondary sex characteristics in males
What does FSH and LH do in females
Effect the ovaries and stimulate the release of oestrogen and progesterone
What does oestrogen do
Travels in blood and promotes breast development and other sex characteristics
What do the endocrine glands do
Release hormones directly into the blood stream
Explain what the ovarian cycle is
A series of events that take place in the ovaries causing the development of follicles and corpus luteum
What long does the ovarian cycle take
28 days
What is the first step of the ovarian cycle
Surrounding the primary oocyte is a single layer of cells called the primary follicle
What is the second step of the ovarian cycle
At puberty, follicle stimulating and lutenising hormone are secreted
What is the third step of the ovarian cycle
In response to FSH and LH, the cells of the primary follicle, enlarge, divide and secrete fluid into the space around the oocyte
What is the fourth step of the ovarian cycle?
More fluid accumulates inside the follicle and the follicle moves to the surface of the ovary
What is the fifth step of the ovarian cycle
At day 14 there is a spike in LH and FSH and this causes ovulation to occur
What is the sixth step of the ovarian cycle
The ruptured follicle forms a blood clot
What is the seventh step of the ovarian cycle
These cells enlarge and form the corpus luteum
What is step 8A of the ovarian cycle
If fertilization does not take place after 8-10 days it will degrade and become the corpus albicom
What is step 8B of the ovarian cycle
If fertilization takes place the corpus luteum remains for 3 months