Amnesia cases, MMS and EMotional and memory

Patient H.M.

• Famous Hippocampus lesion cases

• Intractable epilepsy

• Had a brain operation at the age of 27 but William Scoville

• Reduced seizures but had profound memory loss (antegrade and retrograde amnesia)

H.M and hippocampus and memeory

• Still had language skills, IQ, perception, reasoning ability, and motivation intact (short-term)

• Motor skills, perceptual learning, and priming skills intact BUT had no memory of learning these task

• Normal Non-deceleration but no declarative knowledge

H.M.’s amnesia

1. He learned motor skills, perceptual skills, and priming well and could remember it across days however he had no declarative knowledge of the experience

2. Non-declarative intact

3. Case of memory deficit damage that localized in one part of the brain

Amnesia case of E.P

• Viral encephalitis—brain damage by a virus—that bilaterally affects his hippocampus

• Anterograde and retrograde amnesia

• Post damage, couldn’t remember things or create new memories (A.A.)

• Had little buts of distant past forgotten (A.R.)

The case of H.M and E.P.

• A Specific type of memory is localized in the brain with declarative memories encoded by the hippocampus

• The hippocampus doent’t stores all kinds of memory

• Skill, perceptual learning, etc. are encoded by other parts of the brain

• This helps to discover the Multiple Memory symptoms perspective (MMSP)

Multiple Memory Systems

• A complete understanding of memory is only achieved by recognizing that the content of the experience is important

• Memories are segregated into different brain regions according to their content

Memory System

• Declarative Memory—hippocampus

• Emotional Memory —amygdala

Episodic and emotional aspects of
memory

• Double dissociation of lension in Hippocampus, Amygdala and both

• Study made too

  • SM046—amygdala damage —-Urbach-Wiethe

  • WCI606—Hoppocamous damage —Heart attack

  • RHI951—Both damaged —Herpes simplex encephalitis

Pavlovian conditioning procedure

• behavioral learning technique that uses association to produce a new response—an unconditioned response

  • Conditional stimulus (CS)

  • Unconditional stimulus (US)

Measuring emotional response

• Via Galvanic skin response

  • skin conductance

  • correlated with emotional responding

  • Lie detector test

• Galvanic skin response ==emotional memory

• Questions = declarative memory

emotional memory even though you don’t
remember the experience (non-declarative) possible?

Yes