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antidepressants can be used to treat
anxiety disorders
effective for treating anxiety disorders without the CNS- depressant effects for the potential for abuse and withdrawal symptoms
Buspirone
what are the side effects of buspirone
dizziness
drowsiness
nausea
excitement
headache
what are the cautions when taking buspirone
caution with driving or operating heavy machinery
avoid alcohol
DO NOT USE MAOIs : 2 week period
What are the interactions of haldol and buspirone
increase serum levels of haldol
what is the drug of choice for treating GAD
buspirone
how long does it take for buspirone to take effect
3-6 weeks
beta blocker, that blocks B1 receptors which may prevent fear conditioning
used to treat physical anxiety symptoms or performance anxiety
propranolol
what are the cautions for propanolol
can worsen depression
what are the side effects of propanalol
bradycardia
hypotension
fatigue
what is the daily dosing for propanalol
20-40 mg/day
used in anxiety related to alcohol withdrawal
blocks histamine receptors
not as effective as benzos
can be lethal in OD
hydroxyzine
what are the side effects of hydroxyzine
sedation
blurry vision
dry mouth
what is the dosing of hydroxyzine
50-100 QID
increases availability of GABA
rapid onset
CNS depressant
benzodiazepine
abrupt discontinuation of benzos can lead to
recurrence of target symptoms
what are the benzos
lorazepam (ativan)
alprazolam (xanax)
clonazepam (klonopin)
diazepam (valium)
chlordiazepoxide (librium)
flurazepam (dalmane)
triazolam (halcion)
what are the side effects of benzos
CNS depression
ataxia
tolerance
what are the cautions of benzos
avoid other CNS depressants
risk of sedation
do not stop abruptly
can cause dependence
what are the sedative-hypnotics
benzos
GABA enhancers
melatonergic hypnotics
antihistamines
orexin receptor antagonists
used as a supplement for depression, pain, anxiety, insomnia, and PMS by causing serotonin, dopamine, and norepinephrine modulation
st johns wort
causes risk of serotonin syndrome with other serotonergic drugs
st johns wort
used for anxiety reduction due to interactions with dopaminergic transmission, inhibition of MAO-B enzyme system and GABA receptor modulation
Kava
what supplement can cause a risk of severe liver injury, thrombocytopenia, leukopenia, and hearing impairments
kava