The testes secrete Müllerian inhibiting substance (MIS) (Vilain, 2000). MIS causes the Müllerian ducts to degenerate, while the **Wolffian ducts,** supported by testosterone, turn into the epididymis, the vas deferens, and the ejaculatory duct. The tubercle becomes the glans penis, the folds form the shaft of the penis, and the swell- ing develops into the scrotum